We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

First-Ever Serology Test Built on Multiparameter Flow Cytometry Platform Differentiates Between COVID-19 Infection and Vaccination Antibodies

By LabMedica International staff writers
Posted on 19 Jul 2021

Illustration

A novel test can measure and track an individual's immune response to the COVID-19 vaccine, now and over time.

FlowMetric Life Sciences Inc. (Doylestown, PA, USA) has launched VaxEffect COVID-19 Vaccine Immune Response Test which will provide a personalized, and clinically accurate readout of a person's COVID-19 specific antibody levels, either generated in response to the COVID-19 vaccine or to prior exposure to the SARS-CoV-2 virus. With simple, repeat testing, changes in these antibody levels can be tracked over time utilizing easy-to-read longitudinal reports, to better inform vaccine-based healthcare decisions and to support the optimal use of booster vaccinations as they become available.

Unlike other antibody tests, VaxEffect is the first COVID serology test built on a multiparameter flow cytometry platform that is designed to differentiate between infection and vaccination based on an antibody profile. Using this proven, powerful, and precise technology, the VaxEffect Test is both 99%+ sensitive and 99%+ specific.

"The VaxEffect test will be especially important for patients with immune compromised conditions such as those fighting cancer, diabetes, auto-immune disorders, or those that are immunosuppressed due to organ transplantation, who may have not generated a strong immune response to the vaccine," said Grant Morgan, Ph.D., General Manager of VaxEffect and EVP of FlowMetric Life Sciences Inc.

Related Links:
FlowMetric Life Sciences Inc.

Visit expo >

Gold Member

SARS‑CoV‑2/Flu A/Flu B/RSV Sample-To-Answer Test

SARS‑CoV‑2/Flu A/Flu B/RSV Cartridge (CE-IVD)

Verification Panels for Assay Development & QC
Seroconversion Panels

New

C-Reactive Protein Assay

OneStep C-Reactive Protein (CRP) RapiCard InstaTest

New

Nutating Mixer

Enduro MiniMix

Latest COVID-19 News

Channels

Clinical Chemistry

view channel

Image: A one-step confirmatory laboratory test could definitively diagnose active syphilis infection within 10 minutes (Photo courtesy of Adobe Stock)

First Comprehensive Syphilis Test to Definitively Diagnose Active Infection In 10 Minutes

In the United States, syphilis cases have surged by nearly 80% from 2018 to 2023, with 209,253 cases recorded in the most recent year of data. Syphilis, which can be transmitted sexually or from mother... Read more

Image: QIP-MS could predict and detect myeloma relapse earlier compared to currently used techniques (Photo courtesy of Adobe Stock)

Mass Spectrometry-Based Monitoring Technique to Predict and Identify Early Myeloma Relapse

Myeloma, a type of cancer that affects the bone marrow, is currently incurable, though many patients can live for over 10 years after diagnosis. However, around 1 in 5 individuals with myeloma have a high-risk... Read more

Image: The tiny clay-based materials can be customized for a range of medical applications (Photo courtesy of Angira Roy and Sam O’Keefe)

‘Brilliantly Luminous’ Nanoscale Chemical Tool to Improve Disease Detection

Thousands of commercially available glowing molecules known as fluorophores are commonly used in medical imaging, disease detection, biomarker tagging, and chemical analysis. They are also integral in... Read more

Image: The research team has developed the uCR-Chip device to enhance kidney function testing (Photo courtesy of University of Manitoba)

Low-Cost Portable Screening Test to Transform Kidney Disease Detection

Millions of individuals suffer from kidney disease, which often remains undiagnosed until it has reached a critical stage. This silent epidemic not only diminishes the quality of life for those affected... Read more

Molecular Diagnostics

view channel

Image: The study helps to clarify the ideal timepoint for ctDNA testing following a surgical procedure (Photo courtesy of Shutterstock)

Liquid Biopsy Assay Detects Recurrence in CRC Patients Prior to Imaging

The detection of circulating tumor DNA (ctDNA) after treatment is a strong indicator of recurrence in colorectal cancer (CRC), but it often goes undetected due to the low traces of ctDNA present in the blood.... Read more

Ultra Fast Synovial Fluid Test Diagnoses Osteoarthritis and Rheumatoid Arthritis In 10 Minutes

Studies indicate that more than 50% of individuals aged 65 and older experience symptoms of osteoarthritis, while rheumatoid arthritis is a serious chronic condition affecting approximately 1 in 100 people... Read more

Genetic-Based Tool Predicts Survival Outcomes of Pancreatic Cancer Patients

A tumor marker is a substance found in the body that may signal the presence of cancer. These substances, which can include proteins, genes, molecules, or other biological compounds, are either produced... Read more

Image: Prostate cancer can be diagnosed at an early stage through a simple urine sample (Photo courtesy of Shutterstock)

Urine Test Diagnoses Early-Stage Prostate Cancer

Prostate cancer is one of the leading causes of death among men worldwide. A major challenge in diagnosing the disease is the absence of reliable biomarkers that can detect early-stage tumors.... Read more

Hematology

view channel

Image: The 3-parameter CCRS model was devised specifically for patients diagnosed with clonal cytopenia (Photo courtesy of 123RF)

New Scoring System Predicts Risk of Developing Cancer from Common Blood Disorder

Clonal cytopenia of undetermined significance (CCUS) is a blood disorder commonly found in older adults, characterized by mutations in blood cells and a low blood count, but without any obvious cause or... Read more

Image: The technology has the unique ability to detect challenging RhD variants that are typically excluded by other commercial tests (Photo courtesy of BillionToOne)

Non-Invasive Prenatal Test for Fetal RhD Status Demonstrates 100% Accuracy

In the United States, approximately 15% of pregnant individuals are RhD-negative. However, in about 40% of these cases, the fetus is also RhD-negative, making the administration of RhoGAM unnecessary.... Read more

Image: Leukocyte count represents an easily accessible, inexpensive clinical marker (Photo courtesy of 123RF)

WBC Count Could Predict Severity of COVID-19 Symptoms

The global health crisis caused by the SARS-CoV-2 virus continues to impact millions of people worldwide, with many experiencing persistent symptoms months after the initial diagnosis. Cognitive impairment... Read more

Image: The high precision platelet counting technology reduces risks that can lead to errors in cancer diagnoses (Photo courtesy of Adobe Stock)

New Platelet Counting Technology to Help Labs Prevent Diagnosis Errors

Accurate platelet count testing is a significant challenge for laboratories. Inaccurate results can lead to misdiagnosis, missed diagnoses, and delayed treatment for a variety of potentially fatal conditions,... Read more

Immunology

view channel

Image: The cancer stem cell test can accurately choose more effective treatments (Photo courtesy of University of Cincinnati)

Stem Cell Test Predicts Treatment Outcome for Patients with Platinum-Resistant Ovarian Cancer

Epithelial ovarian cancer frequently responds to chemotherapy initially, but eventually, the tumor develops resistance to the therapy, leading to regrowth. This resistance is partially due to the activation... Read more

Machine Learning-Enabled Blood Test Predicts Immunotherapy Response in Lymphoma Patients

Chimeric antigen receptor (CAR) T-cell therapy has emerged as one of the most promising recent developments in the treatment of blood cancers. However, over half of non-Hodgkin lymphoma (NHL) patients... Read more

Post-Treatment Blood Test Could Inform Future Cancer Therapy Decisions

In the ongoing advancement of personalized medicine, a new study has provided evidence supporting the use of a tool that detects cancer-derived molecules in the blood of lung cancer patients years after... Read more

Cerebrospinal Fluid Test Predicts Dangerous Side Effect of Cancer Treatment

In recent years, cancer immunotherapy has emerged as a promising approach where the patient's immune system is harnessed to fight cancer. One form of immunotherapy, called CAR-T-cell therapy, involves... Read more

Microbiology

view channel

Image: CRP protein in cerebrospinal fluid was found to be a very reliable indicator of bacterial meningitis (Photo courtesy of 123RF)

New Test Diagnoses Bacterial Meningitis Quickly and Accurately

Bacterial meningitis is a potentially fatal condition, with one in six patients dying and half of the survivors experiencing lasting symptoms. Therefore, rapid diagnosis and treatment are critical.... Read more

Image: The lab-in-tube assay could improve TB diagnoses in rural or resource-limited areas (Photo courtesy of Kenny Lass/Tulane University)

Handheld Device Delivers Low-Cost TB Results in Less Than One Hour

Tuberculosis (TB) remains the deadliest infectious disease globally, affecting an estimated 10 million people annually. In 2021, about 4.2 million TB cases went undiagnosed or unreported, mainly due to... Read more

Image: The AI-based method can more accurately detect antibiotic resistance in deadly bacteria such as tuberculosis and staph (Photo courtesy of Adobe Stock)

New AI-Based Method Improves Diagnosis of Drug-Resistant Infections

Drug-resistant infections, particularly those caused by deadly bacteria like tuberculosis and staphylococcus, are rapidly emerging as a global health emergency. These infections are more difficult to treat,... Read more

Breakthrough Diagnostic Technology Identifies Bacterial Infections with Almost 100% Accuracy within Three Hours

Rapid and precise identification of pathogenic microbes in patient samples is essential for the effective treatment of acute infectious diseases, such as sepsis. The fluorescence in situ hybridization... Read more

Pathology

view channel

Image: Release of cell-free DNA and altered blood cells in patients with cancer (Photo courtesy of Carolyn Hruban/Johns Hopkins)

AI-Based Liquid Biopsy Approach to Revolutionize Brain Cancer Detection

Detecting brain cancers remains extremely challenging, with many patients only receiving a diagnosis at later stages after symptoms like headaches, seizures, or cognitive issues appear. Late-stage diagnoses... Read more

Image: The AI model accurately classifies pediatric sarcomas using digital pathology images alone (Photo courtesy of Shutterstock)

AI-Driven Analysis of Digital Pathology Images to Improve Pediatric Sarcoma Subtyping

Pediatric sarcomas are rare and diverse tumors that can develop in various types of soft tissue, such as muscle, tendons, fat, blood or lymphatic vessels, nerves, or the tissue surrounding joints.... Read more

Image: A typical histopathologic slide image of kidney cancer tissue (left) has significant intra-slide heterogeneity (Photo courtesy of UT Southwestern Medical Center)

AI-Based Model Predicts Kidney Cancer Therapy Response

Each year, nearly 435,000 individuals are diagnosed with clear cell renal cell carcinoma (ccRCC), making it the most prevalent subtype of kidney cancer. When the disease spreads, anti-angiogenic therapies... Read more

Image: The ready-to-use DUB enzyme assay kits accelerate routine DUB activity assays without compromising data quality (Photo courtesy of Adobe Stock)

Sensitive and Specific DUB Enzyme Assay Kits Require Minimal Setup Without Substrate Preparation

Ubiquitination and deubiquitination are two important physiological processes in the ubiquitin-proteasome system, responsible for protein degradation in cells. Deubiquitinating (DUB) enzymes contain around... Read more

Technology

view channel

Light Signature Algorithm to Enable Faster and More Precise Medical Diagnoses

Every material or molecule interacts with light in a unique way, creating a distinct pattern, much like a fingerprint. Optical spectroscopy, which involves shining a laser on a material and observing how... Read more

Image: The HIV-1 self-testing chip will be capable of selectively detecting HIV in whole blood samples (Photo courtesy of Shutterstock)

Disposable Microchip Technology Could Selectively Detect HIV in Whole Blood Samples

As of the end of 2023, approximately 40 million people globally were living with HIV, and around 630,000 individuals died from AIDS-related illnesses that same year. Despite a substantial decline in deaths... Read more

Image: Schematic illustration of the chip (Photo courtesy of Biosensors and Bioelectronics, DOI: https://doi.org/10.1016/j.bios.2025.117401)

Pain-On-A-Chip Microfluidic Device Determines Types of Chronic Pain from Blood Samples

Chronic pain is a widespread condition that remains difficult to manage, and existing clinical methods for its treatment rely largely on self-reporting, which can be subjective and especially problematic... Read more

Image: Pictorial representation of the working principle of a functionalized Carbon Dots CDs and EB based Func sensor (Photo courtesy of Toppari/University of Jyväskylä)

Innovative, Label-Free Ratiometric Fluorosensor Enables More Sensitive Viral RNA Detection

Viruses present a major global health risk, as demonstrated by recent pandemics, making early detection and identification essential for preventing new outbreaks. While traditional detection methods are... Read more

Industry

view channel

$Image: The collaboration aims to leverage Oxford Nanopore\'s sequencing platform and Cepheid\'s GeneXpert system to advance the field of sequencing for infectious diseases (Photo courtesy of Cepheid)$

Cepheid and Oxford Nanopore Technologies Partner on Advancing Automated Sequencing-Based Solutions

Cepheid (Sunnyvale, CA, USA), a leading molecular diagnostics company, and Oxford Nanopore Technologies (Oxford, UK), the company behind a new generation of sequencing-based molecular analysis technologies,... Read more

Image: The Grifols-IBL partnership will initially focus on biomarker panels for neurological and oncological conditions (Photo courtesy of Grifols)

Grifols and Tecan’s IBL Collaborate on Advanced Biomarker Panels

Grifols (Barcelona, Spain), one of the world’s leading producers of plasma-derived medicines and innovative diagnostic solutions, is expanding its offer in clinical diagnostics through a strategic partnership... Read more

Image: BIOTIA-ID is an NGS platform that accurately and sensitively diagnoses infectious disease-causing pathogens (Photo courtesy of Adobe Stock)

New Collaboration to Advance Microbial Identification for Infectious Disease Diagnostics

With the rise of global pandemics, antimicrobial resistance, and emerging pathogens, healthcare systems worldwide are increasingly dependent on advanced diagnostic tools to guide clinical decisions.... Read more

Image: The Procollagen-III-peptide (PIIINP) ELISA kit (Photo courtesy of Cisbio Bioassays)

Tecan Acquires ELISA Immunoassay Assets from Revvity's Cisbio Bioassays

Tecan Group (Männedorf, Switzerland) has entered into an agreement to acquire certain assets relating to key ELISA immunoassay products from Cisbio Bioassays SAS (Codolet, France), a subsidiary of the... Read more