BioResearch
In vivo CRISPR/Cas9 Therapy Prevents Arrhythmias in Model
Delivery of the CRISPR/Cas9 gene-editing tool via an adeno-associated viral vector (AAV) directly to heart cells in a mouse model of catecholaminergic polymorphic ventricular tachycardia was found to efficiently and specifically prevent development of arrhythmias. More...14 Nov 2018
Immune Sensitivity Hampers Clinical Applications of CRISPR/Cas9
Findings presented in a recent paper suggest that use of the CRISPR/Cas9 gene-editing tool in clinical settings may be more complicated than previously thought, since most people have a pre-existing immune sensitivity to proteins from the bacterial source of Cas9. More...12 Nov 2018
Novel CDK9 Inhibitor Prevents Cancer Growth
Blocking the activity of cyclin-dependent kinase 9 (CDK9) has been shown to be a way to reactivate tumor suppressor genes silenced be growing tumors, which could spur development of chemotherapeutic agents designed to specifically target this enzyme. More...06 Nov 2018
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In Other News
Dysregulation of Retinoic Acid Signaling in Stem Cells Spurs Tumor Growth
Functional 3D Neural Network Models Generated from Stem Cells
Antisense DNA Drug Cures Prostate Cancer in Model
Researchers Aim to Reduce Variability of Gene Therapy Vectors
Candidate Anticancer Drug Effectively Treats Drug-resistant Pancreatic Cancer
Gene Mutation Reduces Glucose Uptake and Premature Mortality
Long Non-Coding RNA Identified Modulates Synaptic Morphology and Function
Elevated Collagen XIII Levels Linked to Breast Cancer Metastasis
Gene Editing Used to Mimic Dysfunctional Neurodegenerative Calcium Transport
Screening Technique Finds Endothelial Cells Targeted by Nanoparticles
Research Determines Why Different Cancers Display Similar Profiles
Molecular Scaffolds Promise Drug Synthesis in Breast Cancer Treatment
Targeted Delivery of Resveratrol Prevents Lung Cancer in Model
Genetically Engineered Zika Virus Slows Tumor Growth in Model
Mechanism Identified for Control of Nuclear Pore Complexes
Candidate Cancer Drug Blocks Growth and Reverses Drug Resistance
Genome Editing Used to Correct Mitochondrial Mutations
Mitochondrial Peptide Protects Brain from Age-Related Dementias
Nanoplatform Overcomes Kidney Cancer Drug Resistance
In Vitro Technique Details Cancer Cell Attachment and Spread
Antibiotic Characterized for Drug-Resistant Strains of TB
Novel Approach Brings Personalized Melanoma Treatment Closer to Reality
Deleting Liver Protein Improves Glucose Metabolism
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
