New Line of PCR Workstations Provide Contamination-Free Zones on the Bench
By LabMedica International staff writers Posted on 26 Aug 2013 |

Image: Mystaire Misonix MY-PCR Prep Stations are compact laminar flow enclosures that reduce the risk of sample contamination while performing polymerase chain reaction (PCR) experiments (Photo courtesy of Mystaire Misonix).

Image: My-PCR Workstation - how it works: Laboratory air is pulled into MY-PCR workstation at “A” and then forced through the HEPA filter at “B.” Smooth and even Class 100 laminar flow air enters the work area at “C” and then exits the workstation at “D” (Photo courtesy of Mystaire Misonix).
A timely new product for biotech laboratories provides molecular biology investigators with a “personal cleanroom” for use while performing PCR preparations prior to the amplification of DNA and RNA.
Products in the new line of MY‑PCR Prep Stations manufactured by Mystaire Misonix (Creedmoor, NC, USA) establish bench-top personal clean zones that enable the investigator to amplify RNA and DNA while minimizing the potential for background from airborne contaminants.
The workstations, which are available in 61 cm and 81 cm-wide models, are the equivalent of Class 100 vertical laminar flow hoods with timed UV light.
Airborne contaminants are prevented from entering into the work zone through constant positive pressure HEPA filtered air. Each MY-PCR Prep Station is equipped with a built-in 254 nanometer shortwave lamp to effectively decontaminate the work area between amplifications. Safety interlocks are included on all PCR Prep Stations to prevent operator exposure to potentially harmful UV radiation.
The main chamber of MY-PCR Prep is constructed from a continuous piece of polycarbonate to prevent UV light from escaping the chamber during irradiation. Operator access is gained through the folding front polycarbonate sash, overlapped to eliminate gaps in the chamber during operation of the UV light. The work surface is white polypropylene that facilitates cleaning and disinfection.
The manufacturer reminds MY-PCR operators that the workstations are not biological safety cabinets. They are designed to provide process protection only from potential airborne contaminants found in the laboratory space.
Related Links:
Mystaire Misonix
Products in the new line of MY‑PCR Prep Stations manufactured by Mystaire Misonix (Creedmoor, NC, USA) establish bench-top personal clean zones that enable the investigator to amplify RNA and DNA while minimizing the potential for background from airborne contaminants.
The workstations, which are available in 61 cm and 81 cm-wide models, are the equivalent of Class 100 vertical laminar flow hoods with timed UV light.
Airborne contaminants are prevented from entering into the work zone through constant positive pressure HEPA filtered air. Each MY-PCR Prep Station is equipped with a built-in 254 nanometer shortwave lamp to effectively decontaminate the work area between amplifications. Safety interlocks are included on all PCR Prep Stations to prevent operator exposure to potentially harmful UV radiation.
The main chamber of MY-PCR Prep is constructed from a continuous piece of polycarbonate to prevent UV light from escaping the chamber during irradiation. Operator access is gained through the folding front polycarbonate sash, overlapped to eliminate gaps in the chamber during operation of the UV light. The work surface is white polypropylene that facilitates cleaning and disinfection.
The manufacturer reminds MY-PCR operators that the workstations are not biological safety cabinets. They are designed to provide process protection only from potential airborne contaminants found in the laboratory space.
Related Links:
Mystaire Misonix
Latest BioResearch News
- Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns
- Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma
- New Method Simplifies Preparation of Tumor Genomic DNA Libraries
- New Tool Developed for Diagnosis of Chronic HBV Infection
- Panel of Genetic Loci Accurately Predicts Risk of Developing Gout
- Disrupted TGFB Signaling Linked to Increased Cancer-Related Bacteria
- Gene Fusion Protein Proposed as Prostate Cancer Biomarker
- NIV Test to Diagnose and Monitor Vascular Complications in Diabetes
- Semen Exosome MicroRNA Proves Biomarker for Prostate Cancer
- Genetic Loci Link Plasma Lipid Levels to CVD Risk
- Newly Identified Gene Network Aids in Early Diagnosis of Autism Spectrum Disorder
- Link Confirmed between Living in Poverty and Developing Diseases
- Genomic Study Identifies Kidney Disease Loci in Type I Diabetes Patients
- Liquid Biopsy More Effective for Analyzing Tumor Drug Resistance Mutations
- New Liquid Biopsy Assay Reveals Host-Pathogen Interactions
- Method Developed for Enriching Trophoblast Population in Samples
Channels
Clinical Chemistry
view channel
‘Brilliantly Luminous’ Nanoscale Chemical Tool to Improve Disease Detection
Thousands of commercially available glowing molecules known as fluorophores are commonly used in medical imaging, disease detection, biomarker tagging, and chemical analysis. They are also integral in... Read more
Low-Cost Portable Screening Test to Transform Kidney Disease Detection
Millions of individuals suffer from kidney disease, which often remains undiagnosed until it has reached a critical stage. This silent epidemic not only diminishes the quality of life for those affected... Read more
New Method Uses Pulsed Infrared Light to Find Cancer's 'Fingerprints' In Blood Plasma
Cancer diagnoses have traditionally relied on invasive or time-consuming procedures like tissue biopsies. Now, new research published in ACS Central Science introduces a method that utilizes pulsed infrared... Read moreMolecular Diagnostics
view channel
First-of-its-Kind Blood Test Detects Trauma-Related Diseases
In today’s fast-paced world, stress and trauma have unfortunately become common experiences for many individuals. Continuous exposure to stress hormones can confuse the immune system, causing it to misinterpret... Read more
Key Gene Identified in Common Heart Disease Unlocks Life-Saving Diagnostic Potential
Hypertrophic cardiomyopathy (HCM) is the most prevalent hereditary heart disease globally, affecting approximately 1 in 200 individuals, and remains a leading cause of heart transplantation.... Read moreHematology
view channel
New Scoring System Predicts Risk of Developing Cancer from Common Blood Disorder
Clonal cytopenia of undetermined significance (CCUS) is a blood disorder commonly found in older adults, characterized by mutations in blood cells and a low blood count, but without any obvious cause or... Read more
Non-Invasive Prenatal Test for Fetal RhD Status Demonstrates 100% Accuracy
In the United States, approximately 15% of pregnant individuals are RhD-negative. However, in about 40% of these cases, the fetus is also RhD-negative, making the administration of RhoGAM unnecessary.... Read moreImmunology
view channel
Stem Cell Test Predicts Treatment Outcome for Patients with Platinum-Resistant Ovarian Cancer
Epithelial ovarian cancer frequently responds to chemotherapy initially, but eventually, the tumor develops resistance to the therapy, leading to regrowth. This resistance is partially due to the activation... Read more
Machine Learning-Enabled Blood Test Predicts Immunotherapy Response in Lymphoma Patients
Chimeric antigen receptor (CAR) T-cell therapy has emerged as one of the most promising recent developments in the treatment of blood cancers. However, over half of non-Hodgkin lymphoma (NHL) patients... Read moreMicrobiology
view channel
Handheld Device Delivers Low-Cost TB Results in Less Than One Hour
Tuberculosis (TB) remains the deadliest infectious disease globally, affecting an estimated 10 million people annually. In 2021, about 4.2 million TB cases went undiagnosed or unreported, mainly due to... Read more
New AI-Based Method Improves Diagnosis of Drug-Resistant Infections
Drug-resistant infections, particularly those caused by deadly bacteria like tuberculosis and staphylococcus, are rapidly emerging as a global health emergency. These infections are more difficult to treat,... Read more
Breakthrough Diagnostic Technology Identifies Bacterial Infections with Almost 100% Accuracy within Three Hours
Rapid and precise identification of pathogenic microbes in patient samples is essential for the effective treatment of acute infectious diseases, such as sepsis. The fluorescence in situ hybridization... Read morePathology
view channel
Breakthrough Diagnostic Approach to Significantly Improve TB Detection
Tuberculosis (TB) remains the deadliest infectious disease globally, with 10.8 million new cases and 1.25 million deaths reported in 2023. Early detection through effective screening is crucial in identifying... Read more
Rapid, Ultra-Sensitive, PCR-Free Detection Method Makes Genetic Analysis More Accessible
Genetic testing has been an important method for detecting infectious diseases, diagnosing early-stage cancer, ensuring food safety, and analyzing environmental DNA. For a long time, polymerase chain reaction... Read moreTechnology
view channel
Disposable Microchip Technology Could Selectively Detect HIV in Whole Blood Samples
As of the end of 2023, approximately 40 million people globally were living with HIV, and around 630,000 individuals died from AIDS-related illnesses that same year. Despite a substantial decline in deaths... Read more
Pain-On-A-Chip Microfluidic Device Determines Types of Chronic Pain from Blood Samples
Chronic pain is a widespread condition that remains difficult to manage, and existing clinical methods for its treatment rely largely on self-reporting, which can be subjective and especially problematic... Read more
Innovative, Label-Free Ratiometric Fluorosensor Enables More Sensitive Viral RNA Detection
Viruses present a major global health risk, as demonstrated by recent pandemics, making early detection and identification essential for preventing new outbreaks. While traditional detection methods are... Read moreIndustry
view channel
Cepheid and Oxford Nanopore Technologies Partner on Advancing Automated Sequencing-Based Solutions
Cepheid (Sunnyvale, CA, USA), a leading molecular diagnostics company, and Oxford Nanopore Technologies (Oxford, UK), the company behind a new generation of sequencing-based molecular analysis technologies,... Read more
Grifols and Tecan’s IBL Collaborate on Advanced Biomarker Panels
Grifols (Barcelona, Spain), one of the world’s leading producers of plasma-derived medicines and innovative diagnostic solutions, is expanding its offer in clinical diagnostics through a strategic partnership... Read more