LabMedica

Download Mobile App
Recent News Expo Clinical Chem. Molecular Diagnostics Hematology Immunology Microbiology Pathology Technology Industry Focus

Discovery Paves Way for Ultrafast High-Resolution Imaging in Real Time

By LabMedica International staff writers
Posted on 30 Apr 2013
Image: A shaped group of ultrafast electrons. The pattern is meant to look like the iris shutter of a camera, invoking the concept of a fast snapshot (Photo courtesy of Andrew McCulloch).
Image: A shaped group of ultrafast electrons. The pattern is meant to look like the iris shutter of a camera, invoking the concept of a fast snapshot (Photo courtesy of Andrew McCulloch).
A new research advance involving ultrafast high-resolution imaging in real time could soon become a reality.

In research published April 16, 2013, in the journal Nature Communications, researchers from the University of Melbourne (Australia) and the University’s ARC Centre for Excellence in Coherent X-ray Science have revealed that ultrashort durations of electron bunches generated from laser-cooled atoms can be both very cold and ultrafast.

Lead researcher Assoc. Prof. Robert Scholten reported on this astonishing finding was a significant move towards making ultrafast high-resolution electron imaging a reality. He said the finding would enhance the ability of scientists in labs to create high quality snapshots of quick alterations in biologic molecules and specimens. “Electron microscopy, which uses electrons to create an image of a specimen or biological molecule, has revolutionized science by showing us the structure at micro- and even nanometer scales,” Assoc. Prof. Scholten said. “But it is far too slow to show us critical dynamic processes, for example the folding of a protein molecule which requires time resolution of picoseconds [billionth of a billionth of a second]. “Our discovery opens up the possibility to dramatically enhance the technology.”

Researchers remarked that imaging technology at this level is like making a “molecular movie.” The temperature of the electrons determines how sharp the images can be, while the electron pulse duration has a similar effect to shutter speed. The scientists have been able to merge these two facets of speed and temperature, generating ultrafast electron pulses with cold electrons, creating opportunities for new developments in the field.

Related Links:

University of Melbourne
ARC Centre for Excellence in Coherent X-ray Science


New
Gold Member
Clinical Drug Testing Panel
DOA Urine MultiPlex
POC Helicobacter Pylori Test Kit
Hepy Urease Test
Automatic CLIA Analyzer
Shine i9000
Urine Chemistry Control
Dropper Urine Chemistry Control

Channels

Molecular Diagnostics

view channel
Image: The diagnostic device can tell how deadly brain tumors respond to treatment from a simple blood test (Photo courtesy of UQ)

Diagnostic Device Predicts Treatment Response for Brain Tumors Via Blood Test

Glioblastoma is one of the deadliest forms of brain cancer, largely because doctors have no reliable way to determine whether treatments are working in real time. Assessing therapeutic response currently... Read more

Immunology

view channel
Image: Circulating tumor cells isolated from blood samples could help guide immunotherapy decisions (Photo courtesy of Shutterstock)

Blood Test Identifies Lung Cancer Patients Who Can Benefit from Immunotherapy Drug

Small cell lung cancer (SCLC) is an aggressive disease with limited treatment options, and even newly approved immunotherapies do not benefit all patients. While immunotherapy can extend survival for some,... Read more

Microbiology

view channel
Image: New evidence suggests that imbalances in the gut microbiome may contribute to the onset and progression of MCI and Alzheimer’s disease (Photo courtesy of Adobe Stock)

Comprehensive Review Identifies Gut Microbiome Signatures Associated With Alzheimer’s Disease

Alzheimer’s disease affects approximately 6.7 million people in the United States and nearly 50 million worldwide, yet early cognitive decline remains difficult to characterize. Increasing evidence suggests... Read more

Technology

view channel
Image: Vitestro has shared a detailed visual explanation of its Autonomous Robotic Phlebotomy Device (photo courtesy of Vitestro)

Robotic Technology Unveiled for Automated Diagnostic Blood Draws

Routine diagnostic blood collection is a high‑volume task that can strain staffing and introduce human‑dependent variability, with downstream implications for sample quality and patient experience.... Read more

Industry

view channel
Image: Roche’s cobas® Mass Spec solution enables fully automated mass spectrometry in routine clinical laboratories (Photo courtesy of Roche)

New Collaboration Brings Automated Mass Spectrometry to Routine Laboratory Testing

Mass spectrometry is a powerful analytical technique that identifies and quantifies molecules based on their mass and electrical charge. Its high selectivity, sensitivity, and accuracy make it indispensable... Read more