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Microbiology

Image: A digitally colorized, transmission electron microscopic (TEM) image, which reveals some of the ultrastructural morphology displayed by an Ebola virus virion (Photo courtesy of Cynthia Goldsmith / CDC).

Simple and Inexpensive Ebola Virus Disease Test Developed

Ebola and Marburg viruses can cause severe bleeding and organ failure, with fatality rates reaching 90% in some outbreaks. The diseases spread through direct contact with bodily fluids of an infected person, monkey, gorilla, chimpanzee or bat. More...
21 May 2019
Image: The HumaLoop M: The easy-to-use Loopamp technology for primary and district laboratories (Photo courtesy of Human Diagnostics).

LAMP Malaria Test Detects Less-Diagnosed Species

A new loop-mediated isothermal amplification (LAMP) molecular assay has been developed that can detect Plasmodium vivax, a species of the parasite that causes malaria. More...
16 May 2019
Image: QuantiFERON-TB Gold (QFT) is a simple blood test that aids in the detection of Mycobacterium tuberculosis, the bacteria which causes tuberculosis (TB). QFT is an interferon-gamma (IFN-γ) release assay, commonly known as an IGRA, and is a modern alternative to the tuberculin skin test (Photo courtesy of Qiagen).

Bronchoalveolar Lavage Explored for TB Diagnosis

Tuberculosis (TB) is among the top 10 causes of death worldwide, and the leading cause from a single infectious agent. In 2017, TB caused an estimated 1.3 million deaths among Human Immunodeficiency Virus (HIV)-negative people, and an additional 300,000 deaths among HIV-positive people. More...
15 May 2019
Image: The RealTime HBV is an in vitro polymerase chain reaction (PCR) assay for the quantitation of Hepatitis B Virus (HBV) DNA in human plasma or serum from HBV-infected individuals (Photo courtesy of Abbott Molecular).

Serum HBV RNA Quantification Monitors Chronic Hepatitis B Infection

Chronic hepatitis B viral infection is a global health problem, especially in the Asian-Pacific region. Approximately 1.2 million people in the USA and 350 million people worldwide have Hepatitis B. and about 650,000 people die annually from HBV infection related liver failure, liver cirrhosis and liver cancer. More...
15 May 2019
Image: A photomicrograph of human papilloma virus associated oropharyngeal cancer. The tissue has been stained to show the presence of the virus by in situ hybridization (Photo courtesy of Jennifer L. Hunt, MD).

Oral HPV-DNA Persists after Oropharyngeal Cancer Treatment

Head and neck cancers affect some 53,000 people in the USA each year, according to the National Cancer Institute, and human papilloma virus (HPV) has been implicated in many of those cases. The diagnosis of cancer can be confirmed by tissue biopsy. More...
14 May 2019
Image: The MinION is the only portable real-time device for DNA and RNA sequencing (Photo courtesy of Oxford Nanopore).

Sequencing Shows Promise for Diagnosing Prosthetic Joint Infections

A method is being developed for diagnosing infections associated with prosthetic joint implants that promises to provide results in a matter of hours as opposed to a week or more. More...
07 May 2019
Image: A Pgp3 LFA-dipstick test. After approximately 4 hours, the LFA-dipstick was inserted into the well for 15 to 20 minutes, and then LFA buffer was added (A). LFAs were read when the membrane was completely cleared of background staining (B) (Photo courtesy of the CDC).

Rapid Test for Chlamydia Antigen Antibodies Optimized

Trachoma, resulting from repeated infection with the bacterium Chlamydia trachomatis (Ct), is the leading infectious cause of blindness. Trachoma is targeted for elimination as a public health problem by 2020. More...
07 May 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.