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Microbiology

Image: The MinION is the only portable real-time device for DNA and RNA sequencing (Photo courtesy of Oxford Nanopore).

Sequencing Shows Promise for Diagnosing Prosthetic Joint Infections

A method is being developed for diagnosing infections associated with prosthetic joint implants that promises to provide results in a matter of hours as opposed to a week or more. More...
07 May 2019
Image: A Pgp3 LFA-dipstick test. After approximately 4 hours, the LFA-dipstick was inserted into the well for 15 to 20 minutes, and then LFA buffer was added (A). LFAs were read when the membrane was completely cleared of background staining (B) (Photo courtesy of the CDC).

Rapid Test for Chlamydia Antigen Antibodies Optimized

Trachoma, resulting from repeated infection with the bacterium Chlamydia trachomatis (Ct), is the leading infectious cause of blindness. Trachoma is targeted for elimination as a public health problem by 2020. More...
07 May 2019
Image: A visualization of morulae in the cytoplasm of a granulocyte during examination of blood smears is highly suggestive of a diagnosis of Human Granulocytic Anaplasmosis (Photo courtesy of the US Centers for Disease Control and Prevention).

Diagnostic Methods Compared for Human Granulocytic Anaplasmosis

Human granulocytic anaplasmosis (HGA) is a tick-borne intracellular bacterial infection caused by Anaplasma phagocytophilum. The disease is present in North America, Europe, and northern Asia, areas with Ixodes ricinus ticks, the primary vector for transmission to humans. More...
02 May 2019
Image: A graphic representation of Strain- and Species-Level Variation in the Microbiome of Diabetic Wounds Is Associated with Clinical Outcomes and Therapeutic Efficacy (Photo courtesy of the University of Pennsylvania).

Certain Bacteria Strains Associated with Diabetic Wounds

About 10% of Americans have been diagnosed with diabetes, and one quarter of these patients will develop a wound that does not heal. In the worst case outcome, which occurs in up to 25% percent of these wound-developing patients, the wounds will require an amputation. More...
01 May 2019
Image: The Qubit 4 Flurometer is designed to accurately measure DNA, RNA, and protein quantity, and now also RNA integrity and quality, using the highly sensitive Qubit assays (Photo courtesy of Thermo Fisher Scientific).

Human Microbiome Features Stratify Children with IBS

Irritable bowel syndrome (IBS) is a disruptive gastrointestinal condition characterized by bloating, changes in bowel habits, and pain that affects up to 20% of the world's population (children and adults). Increasing evidence indicates that the onset and symptoms of IBS are related to the gut microbiome. More...
30 Apr 2019
Image: The LuxScan 10K-B confocal laser scanner for microarray imaging and data analysis of DNA, protein, cell and tissue arrays (Photo courtesy of Capital Bio).

Biochip Assay Rapidly Detects Mycobacterial Isolates

Tuberculosis (TB) has bounced back in the past several decades and has become the main cause of death from one single infectious disease, mainly due to the epidemic of human immunodeficiency virus (HIV). More...
24 Apr 2019
Image: An area of mild erythema around varicella lesion on the thigh of a young boy progressed to necrotizing fasciitis caused by group A Streptococcus (Photo courtesy of Dr. E. P. Dellinger, MD).

Multiplex Assay Detects Pathogens in NF Patients

Necrotizing fasciitis (NF) is a life-threatening deep soft tissue infection characterized by rapidly progressive necrosis of the fascia and the adjacent soft tissues. NF of the extremities is associated with high mortality rates, and immediate surgical intervention is required upon detection of NF infections. More...
23 Apr 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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