Molecular Diagnostics

Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants
A single normal cell randomly acquires a series of mutations that allows it to proliferate and to be transformed into a cancer cell (i.e., founding clone), which initiates tumor progression and recurrence. More...25 Nov 2019

Aqueous Humor Is Superior to Blood to Diagnose Retinoblastoma
Retinoblastoma is a cancer that forms in the light-detecting cells in the back of the eye. It often appears in children under two years of age and can lead to blindness or eye removal. Most cancers are biopsied and studied so that medical scientists can design targeted treatments. More...25 Nov 2019

Novel Nanosensing Technologies Developed for Exosome Detection and Profiling
Exosomes are extracellular vesicles (EVs) that are produced in the endosomal compartment of most eukaryotic cells. Liquid biopsy technologies have been developed to do high-throughput exosome protein profiling and point-of-care (POC) exosome analysis. More...20 Nov 2019

Blood Biomarkers Identify Individuals at Risk of Heart Attack or Stroke
A recent study found that elevated levels of high-sensitivity cardiac troponin T or NT-proBNP characterized individuals with elevated blood pressure (BP) or hypertension not currently recommended for anti-hypertensive medication who are at high risk for cardiovascular (CV) events such as heart attack or stroke. More...20 Nov 2019

Early-Onset Alzheimer's Mutation Possibly Mitigated by APOE Variant
Alzheimer's disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills, and, eventually, the ability to carry out the simplest tasks. In most people with Alzheimer's, symptoms first appear in their mid-60s. More...19 Nov 2019
In Other News
Project Set to Develop Algorithm Able to Accurately Predict and Detect Sepsis
Phoenix CPO Test Evaluated for Detection of Carbapenemase Producers
Rapid Fluorescence Fingerprinting Assay for Identification of Synthetic Cannabinoid Receptor Agonists
Newly Identified Biomarker Distinguishes Potentially Aggressive Meningiomas
Rapid DNA Flow Technology Platform Detects Tick-Borne Bacterial Pathogens
Researchers Recommend the Membrane Protein Flotillin as a Biomarker for Alzheimer’s Disease
Inexpensive LAMP-Based Schistosomiasis Tests Developed
Chromosomal Abnormalities Associated with Recurrent Miscarriage
Use of Cell-free DNA Liquid Biopsy to Predict Glioblastoma Progression
Prostate Cancer Methylation Levels Linked to Epigenetic Profiles
Metabolomic Profiling Identifies ALL Patients at Risk for MRD and Cancer Relapse
Enterovirus D type 111 Genetically and Phenotypically Characterized
Whole-exome Sequencing Identifies Mysterious Pancreatitis Mutation
Metastatic Tumor Profiles Lead to Potential Treatment Targets
Full Analytical Data Validated for Target Selector ctDNA Assays
Blood and Urine Metabolic Biomarkers Monitor Short-term Dietary Changes
Large-Scale Schizophrenia Exome Sequencing Identifies New Risk Genes
Nasopharyngeal Pneumococcal Density Associated with Invasive Lung Disease
Post-Treatment Colon Cancer Recurrence Identified by ctDNA Detection
Degree of Amyloid-Beta Misfolding Is Predictor of Alzheimer’s Disease Risk
Rapid Immunoassay Shows Potential for Lyme Disease Diagnosis
Methods Explored for Gram-Negative Non-Fermentative Bacteria ID
Trial Finds High Analytical Performance in Whole-Genome Sequencing
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.







