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Molecular Diagnostics

Image: A micrograph showing an adenocarcinoma of the lung (Photo courtesy of Wikimedia Commons).

Metabolomics-Based Blood Test Used for Diagnosis of NSCLC

A metabolomics-based blood test may reduce the need to rely on low-dose CT (computed tomography) scans for the diagnosis of non-small-cell lung cancer (NSCLC). More...
22 Jul 2019

Biomarker Predicts Ability of Endurance Training to Improve Metabolic Health

Levels of the biomarker dimethylguanidino valeric acid in the blood are predicative of whether an individual can improve overall metabolic health through endurance training. More...
22 Jul 2019
Image: A model of human C-reactive protein (CPR) (Photo courtesy of Wikimedia Commons).

Measurement of Circulating CRP Reduces Unnecessary Antibiotic Treatments

By determining levels of C-reactive protein (CRP) in the blood, it was possible to reduce the number of unnecessary prescriptions for antibiotics that were issued in the United Kingdom to individuals experiencing flare-ups of their chronic obstructive pulmonary disease (COPD). More...
22 Jul 2019
Image: EndoPredict is a next-generation breast cancer recurrence test that integrates tumor biology and pathology to accurately predict early and late (5-15 years) recurrence with an individualized absolute chemotherapy benefit (Photo courtesy of Myriad Genetics).

Multigene Expression Profiling Assays Compared for Cancer

A cost-effectiveness analysis recently published has added another factor to the ongoing competition and debate between various companies offering genomic breast cancer recurrence assays. More...
19 Jul 2019
Image: Ultra-Sensitive TP53 sequencing for cancer detection reveals progressive clonal selection in normal tissue over a century of human lifespan (Photo courtesy of University of Washington).

Low-Frequency TP53 Gene Mutations Also Found in Healthy Women

Worldwide, more than 250,000 new cases of ovarian cancer are diagnosed each year, and two-thirds of these women die from the disease. This high mortality is largely due to the high frequency of metastasis before diagnosis and a lack of effective screening and early detection methods. More...
19 Jul 2019
Image: The Epi ProColon screening test is a blood-based colorectal cancer screening test is an in vitro polymerase chain reaction assay for the qualitative detection of Septin9 gene methylation in DNA isolated from the patient’s plasma (Photo courtesy of Epigenomics).

Blood Test Complements Colonoscopy for Lynch Syndrome Patients

Lynch syndrome (LS) subjects are genetically predisposed to a high risk for colorectal cancer (CRC) and regular colonoscopy is currently the only CRC screening option recommended for these subjects, although compliance is suboptimal. More...
16 Jul 2019
Image: A scanning electron micrograph (SEM) of a human T-cell from the immune system of a healthy donor (Photo courtesy of [U.S.] NIAID).

Regulatory T-cell Responsiveness Predicts Risk of Cancer Relapse

The risk of future breast cancer relapse can be predicted by analyzing the signaling responsiveness of peripheral blood Treg II cells (CD45RA−FOXP3hi Treg cells) to immunosuppressive T helper type 1 (TH1) and T helper type 2 (TH2) cytokines. More...
15 Jul 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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