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Molecular Diagnostics

Image: The top and front view of the three-dimensional structure of the pentameric nicotinic acetylcholine receptor, which is damaged or destroyed in myasthenia gravis (Photo courtesy of Wikimedia Commons).

Metabolites Pattern Distinguishes Myasthenia Gravis from RA Patients

A team of Canadian researchers used a pattern of 12 metabolites to distinguish myasthenia gravis patients from healthy individuals or from those with rheumatoid arthritis. More...
09 Sep 2019
Image: Risk stratification integrating genetic data for factor VIII inhibitor development in patients with severe hemophilia (Photo courtesy of Paris-Saclay University).

Genetics Affect Risk of Developing Factor VIII Inhibitors

For severe hemophilia A (HA) patients, the current standard of care includes regular prophylactic infusions of factor VIII (FVIII) products in order to prevent spontaneous bleeds or on demand infusions to treat bleeds. More...
06 Sep 2019
Image: The E.Z.N.A Stool Extraction Kit Isolates DNA from stool samples using spin columns (Photo courtesy of Omega Bio-tek).

Type 1 Diabetes Risk Reflected in Gut Microbiome

Type 1 diabetes mellitus (T1D) is an autoimmune disorder characterized by the destruction of insulin-producing ß-cells in the pancreas, resulting in a life-long dependence on exogenous insulin. T1D is an autoimmune condition that can develop at any age. More...
06 Sep 2019
Image: The cobas e 411 analyzer is a fully automated analyzer that uses a patented Electrochemiluminescence technology for immunoassay analysis (Photo courtesy of Roche Diagnostics).

Persistent C-Peptide Secretion in Type 1 Diabetes Genetic-Related

Studies using sensitive assays for C-peptide have shown that some degree of residual insulin secretion commonly persists for more than five years after diagnosis of type 1 diabetes. There is variation in C-peptide persistence, the determinants of which are poorly understood but may be partly genetically determined. More...
04 Sep 2019
Image: The VERSANT HCV Genotype 2.0 Line Probe Assay (Photo courtesy of Siemens Healthcare Diagnostics).

Sequencing Methods for Hepatitis C Virus Genotyping Compared

Due to its high rate of mutation, hepatitis C virus (HCV) forms viral quasispecies, classified based on the highly variable regions in the envelope protein and nonstructural 5B protein (NS5B). As a result of this large genetic variability, seven genotypes and more than 67 subtypes have been identified. More...
04 Sep 2019
Image: Neurons from rat brain tissue stained green with antibody to ubiquitin C-terminal hydrolase L1 (UCH-L1), which highlights the cell body strong and the cell processes more weak. Astrocytes are stained in red with antibody to the GFAP protein found in cytoplasmic filaments. Nuclei of all cell types are stained blue with a DNA binding dye (Photo courtesy of Wikimedia Commons).

Concussive Injuries Diagnosed by Measuring a Brain Protein in Blood

A simple blood test detects brain injury by measuring the levels of two brain proteins, which are released into the circulation following head trauma. More...
02 Sep 2019
Image: A micrograph of a low malignant potential (LMP) mucinous ovarian tumor. The micrograph shows: Simple mucinous epithelium (right) and mucinous epithelium that pseudo-stratifies (left - diagnostic of a LMP tumor). Epithelium in a frond-like architecture is seen at the top of image (Photo courtesy of Wikimedia Commons).

Protein Biomarker Panel Enables Early Detection of Cancer

Analysis of biomarker expression data from serum obtained from ovarian cancer patients has enabled development of an early detection tool for epithelial ovarian cancer (EOC). More...
02 Sep 2019
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Quality Control Material
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Hepy Urease Test
Urine Chemistry Control
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Gram-Negative Blood Culture Assay
LIAISON PLEX Gram-Negative Blood Culture Assay


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.