Molecular Diagnostics
Memory Loss in Alzheimer’s Disease Linked to Both Amyloid Plaques and Tau Tangles
A team of neurodegenerative disease researchers has linked the APOE-epsilon-4 gene to increased formation of toxic tau protein aggregates (tangles) as well as amyloid-beta plaques in individuals with Alzheimer’s disease (AD). More...31 Dec 2019
Elevated Levels of Lipoprotein(a) Increase Cardiovascular Disease Risk in Patients with Type I Diabetes
Results obtained by a team of Swedish researchers indicated that individuals with type I diabetes were at greater risk of developing cardiovascular disease (CVD) if they had elevated levels of lipoprotein(a) in their blood. More...30 Dec 2019
Novel Liquid Biopsy Method for Detection of Cancer MicroRNA Biomarkers
The potential usefulness of the “liquid biopsy” approach for detection of cancer biomarkers in the blood has been increased by the development of a method for capturing and counting cancer-associated microRNAs. More...30 Dec 2019
Stool DNA Test Helps Detect Precancerous Lesions
Colorectal cancer (CRC) is the third most common cancer and is one of the leading causes of cancer-related mortality. Although CRC incidence is increasing, a decrease in mortality has been observed due to the implementation of CRC screening and improved therapies. More...27 Dec 2019
Germline Genetic Testing Assesses Inherited Risk for Myeloid Malignancies
Inherited risk for hematologic malignancies was historically thought to be relatively rare; however, the increased use of next-generation sequencing has identified more patients with germline genetic mutations that are known to increase cancer risk. More...26 Dec 2019
A Rapid Method for Isolating Viral DNA-enriched Salivary Exosomes for Diagnosis and Monitoring of Oropharyngeal Cancer
A novel method, based on the combination of microfluidics and acoustics, for concentrating exosomes containing viral DNA from the saliva of oropharyngeal cancer patients was found to be 15 times more sensitive than the current gold standard differential centrifugation method. More...24 Dec 2019
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In Other News
New Human Autoinflammatory Disease Identified
Distinct Myelodysplastic Syndrome Subtypes Identified by Genomic, Transcriptomic Analysis
Combining RNA Sequencing with a Learning Algorithm to Identify Single Cells in Biopsy Specimens
Genome Wide Sequencing Study Reveals Why Some Cystic Fibrosis Patients Develop Fewer Lung Infections
Virome Shifts Analyzed in Children with Islet Autoimmunity
Exposure to Human Cytomegalovirus Increases Aggressiveness of Glioblastoma and Predicts a Poorer Outcome of the Disease
Single-Cell Analysis Uncovers Regulatory Program in Rare Leukemia
Novel Biomarker Predicts Dementia Risk
Genetic Biomarkers Associated with Autism Spectrum Disorders Identified
Implement Diagnostics System Improves Infectious Disease Testing
Mutations Causing Loss of Tumor Suppressor Gene Increase Aggressiveness of Rare Bile Duct Cancer
Childhood Kidney Cancer Arises from Altered Normal Tissue
Predicting Age by Profiling Circulating Plasma Proteins
A Rapid Method for Selecting the Proper Antibiotic to Treat Multidrug Resistant Bacteria
Chronic Comorbidities Are Prevalent Among People with Chagas Disease
A One-step Rapid Point-of-Care Assay for Diagnosis of Celiac Disease
Diagnosis and Monitoring of Patients with Hepatitis C Virus
TP53 Gene Promoter Methylation Impacts Chronic Lymphocytic Leukemia
Three Factors Distinguish MODY, a Rare Diabetes, in Youth
Alzheimer's Disease Gene Expression Varies by Brain Cell Type
Diagnosing Disease Conditions by Analyzing Plasma Protein Expression Patterns
Home Urine Collection for More Accurate Prostate Cancer Detection
Genetic Architectures of Schizophrenia Compared in Different Populations
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.