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Molecular Diagnostics

Image: The cobas e 801 module is a high throughput immunochemistry module that performs a broad range of heterogeneous immunoassay tests (Photo courtesy of Roche Diagnostics).

Low Serum IGF1 Predicts CV Events in RA Women

Hypertension is a significant health threat and an independent predictor of cardiovascular (CV) events including coronary heart disease, stroke, heart failure, and dementia in the general population and in rheumatoid arthritis (RA). More...
06 Aug 2019
Image: The device without a smartphone (left) and with a smartphone attached (right) (Photo courtesy of Rohan Mehra - Division for Strategic Public Relations).

Smartphone-Based Device Used for Influenza Virus Detection

A simple and inexpensive smartphone-based device was able to detect influenza virus particles in clinical samples with almost 100 times greater sensitivity than commercial rapid influenza diagnostic tests. More...
05 Aug 2019
Image: The experimental results of immunostained cells using the electroactive microwell array with barriers (EMAB) device (Photo courtesy of Dr. Soo Hyeon Kim, University of Tokyo).

Novel Microfluidic Device Simplifies Cancer Screening Procedures

A novel microfluidic device is set to simplify screening for cervical cancer by efficiently isolating and trapping single cells for identification using direct immunostaining techniques. More...
05 Aug 2019
Image: The Applied Biosystems Veriti HID 96-Well Thermal Cycler (Photo courtesy of Thermo Fisher Scientific).

Multiplex PCR Developed for Neglected Infectious Diseases

Scrub typhus, murine typhus, and leptospirosis are diagnosed as acute undifferentiated febrile illness. Diagnostic tests for these diseases depend on antibody detection. However, antibody detection is still limited by its tendency to return negative results during the early phase of these diseases. More...
01 Aug 2019
Image: A blood smear of a patient with Sickle Cell Disease. Polychromatophilic reticulocytes are present (small single arrow). Target cell (large single arrow) and sickle cell (double arrow) can be seen in this view (Photo courtesy of John Lazarchick).

Noninvasive Prenatal Test Developed for Sickle Cell Disease Risk

Sickle cell disease (SCD) is an autosomal recessive disease, meaning that a child has to inherit two mutated copies of the hemoglobin gene to develop it, one from each parent. If both parents have sickle cell trait, there is a 25% chance the child will have SCD. More...
01 Aug 2019
Image: The 2100 Bioanalyzer with automated electrophoresis, provides sizing, quantitation, and purity assessments for DNA, RNA, and protein sample (Photo courtesy of Agilent Technologies).

Gene Linked to Severe Liver Damage

Nonalcoholic fatty liver disease (NAFLD) is a chronic, frequently progressive condition resulting from excessive accumulation of fat in hepatocytes. Nonalcoholic steatohepatitis (NASH) is a clinically advanced form of NAFLD characterized by hepatic inflammation with or without scarring that is associated with increased liver-related morbidity and mortality. More...
31 Jul 2019
Image: The two sets of charts compare the recommendations for managing patients with pancreatic cysts based on either CompCyst or standard-of-care pathology (Photo courtesy of the American Association for the Advancement of Science).

Test Improves Accuracy in Identifying Precancerous Pancreatic Cysts

Pancreatic cysts are common and often pose a management dilemma, because some cysts are precancerous, whereas others have little risk of developing into invasive cancers. Early, accurate detection of pancreatic cancer is a high priority. More...
30 Jul 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.