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Molecular Diagnostics

Image: Microsporidian spores stained Calcofluor White M2R (Photo courtesy of Institute Pasteur of Tunis).

Symptomatic Respiratory Pathogen Found in Transplant Recipients

As opportunistic pathogens, microsporidia cause symptomatic infections mainly in patients with impaired immune function; and microsporidial dissemination to the central nervous system, eyes, and respiratory and urinary tracts has been documented in these patients. More...
13 Feb 2019
Image: The Benchmark XT System, a fully automated staining system (Photo courtesy of Ventana Medical Systems).

Genetic Causes of Salivary Gland Carcinoma Discovered

Acinic cell carcinoma is the third most common malignant form of salivary gland cancer. These tumors are similar to normal salivary gland tissue and occur most frequently in the parotid gland. Until now, the molecular causes for the illness were unknown. More...
13 Feb 2019
Image: A diagram of whole-exome sequencing to identify genetic variants (Photo courtesy of NGXBIO).

Whole-Exome Sequencing Evaluates Fetal Structural Anomalies

In about 3% of pregnancies, ultrasound imaging will reveal a significant fetal physical anomaly and knowing the cause of the anomaly can help doctors and parents be better prepared, both during the pregnancy and after delivery. More...
12 Feb 2019
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Direct Blood PCR Detects Thromboembolism-Associated Mutations

Routine genetic testing is recommended in several clinical circumstances, particularly in patients with venous thrombosis at younger age, a strong family history of thrombotic disease, or in women with a history of venous thrombosis during pregnancy. More...
11 Feb 2019
Image: The MAGPIX single or multiplex automated immunoassay reader (Photo courtesy of Bio-Rad).

Assays Detect Inherited Blood Disorders Associated with Malaria

Plasmodium parasites have co-evolved with human hosts and exert a considerable evolutionary pressure on mutations that confer a degree of protection against malaria. More...
07 Feb 2019
Image: Positron Emission Tomography (PET) scans of the brain of a normal patient (left) versus an Alzheimer\'s disease patient, which may have been detected earlier by measuring Neurofilament light chain (NfL) in CSF (Photo courtesy of Science Photo Library).

Blood Test Detects Brain Damage Years before Symptoms

Alzheimer's disease is a major cause of dementia that destroys brain cells and tissue. As the brain damage spreads, it leads to symptoms such as confusion, memory loss, and diminishing capacity to function. Eventually, the person can no longer lead an independent life. More...
07 Feb 2019
Image: Various types of data analysis using BeadStudio Methylation Module (Photo courtesy of Phoebe Lu).

DNA Methylation Test Detects Early Aggressive Prostate Cancer

Liquid biopsies that noninvasively detect molecular correlates of aggressive prostate cancer (PCa) could be used to triage patients, reducing the burdens of unnecessary invasive prostate biopsy and enabling early detection of high-risk disease. More...
06 Feb 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.