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Microbiology

Image: A micrograph of a urine cytology specimen showing a polyomavirus infected cell (Photo courtesy of Wikimedia Commons).

New Liquid Biopsy Assay Reveals Host-Pathogen Interactions

A sensitive new assay employs high-throughput DNA sequencing to identify a large range of viral and bacterial pathogens in clinical samples, distinguish them from host DNA, and determine the degree of host tissue injury due to interaction with the pathogens. More...
09 Sep 2019
Image: NETosis Assay Kit: PMA induces neutrophil extracellular trap (NET) formation in human neutrophils (Photo courtesy of Cayman Chemical).

Differential Immune Responses Triggered against Salmonella enterica

Enteric fevers, caused by the Salmonella enterica serovars Typhi (ST), Paratyphi A (PA) and Paratyphi B (PB), are life-threatening illnesses exhibiting very similar clinical symptoms but with distinct epidemiologies, geographical distributions and susceptibilities to antimicrobial treatment. More...
06 Sep 2019
Image: The E.Z.N.A Stool Extraction Kit Isolates DNA from stool samples using spin columns (Photo courtesy of Omega Bio-tek).

Type 1 Diabetes Risk Reflected in Gut Microbiome

Type 1 diabetes mellitus (T1D) is an autoimmune disorder characterized by the destruction of insulin-producing ß-cells in the pancreas, resulting in a life-long dependence on exogenous insulin. T1D is an autoimmune condition that can develop at any age. More...
06 Sep 2019
Image: A collection of whole saliva by the Salivette (absorbent) method. (a) Saliva is collected by chewing a cotton wool swab. (b) The swab containing saliva is placed in the tube of Salivette. (c) Centrifugation of the assemblage. (d) Saliva is separated from the swab and is ready for analysis (Photo courtesy of Sarstedt).

Optimized Immunoassays Detect HBV in Oral Fluid Samples

It is estimated that there are 257 million chronic hepatitis B (HBV) carriers worldwide, which highlights the substantial health, social, and economic burden of HBV. Screening of infected, cured and vaccinated individuals is necessary to identify the presence of chronically infected reservoirs, immune and susceptible individuals. More...
05 Sep 2019
Image: Aspergillus (Photo courtesy of Kateryna Kon / Fotolia.com).

Novel ELISA Detects Invasive Aspergillosis

Aspergillus spp. is a ubiquitous sac fungus, which is found in soil or compost or on damp walls. Inhalation of spores can lead to severe infections in individuals with a weakened immune system. More...
05 Sep 2019
Image: The VERSANT HCV Genotype 2.0 Line Probe Assay (Photo courtesy of Siemens Healthcare Diagnostics).

Sequencing Methods for Hepatitis C Virus Genotyping Compared

Due to its high rate of mutation, hepatitis C virus (HCV) forms viral quasispecies, classified based on the highly variable regions in the envelope protein and nonstructural 5B protein (NS5B). As a result of this large genetic variability, seven genotypes and more than 67 subtypes have been identified. More...
04 Sep 2019
Image: The gut-infecting bacterium Clostridium difficile shown growing in a petri dish, and is evolving into two separate species with one group highly adapted to spread in hospitals (Photo courtesy of Anne Koerber/LSHTM).

C. Difficile Bacteria Adapted to Spread in Hospitals

Clostridioides difficile, also known as Clostridium difficile, bacteria can infect the gut and are the leading cause of antibiotic-associated diarrhea worldwide. While someone is healthy and not taking antibiotics, millions of 'good' bacteria in the gut keep the C. difficile under control. More...
29 Aug 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.