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Microbiology

Image: A representation of CEACAM5 protein (Photo courtesy of Wikimedia Commons).

Disrupted TGFB Signaling Linked to Increased Cancer-Related Bacteria

Following careful analysis of DNA sequences collected in The Cancer Genome Atlas, researchers have proposed that CEACAM (carcinoembryonic antigen related cell adhesion molecule) proteins disrupt TGFB signaling, which alters the composition of the intestinal microbiome to promote development of colorectal cancer. More...
14 Oct 2019
Image: The Quant-iT PicoGreen dsDNA assay kit (Photo courtesy of Thermo Fisher Scientific).

Stunted Microbiota and Opportunistic Pathogen Colonize C-Section Birth

Immediately after birth, newborn babies experience rapid colonization by microorganisms from their mothers and the surrounding environment. Infants born by Caesarean section have gut microbiomes that differ from those of infants born vaginally, carrying more hospital-associated opportunistic pathogens. More...
10 Oct 2019
Image: A peripheral blood smear showing Wuchereria bancrofti microfilaria, found in a patient with lymphatic filariasis (Photo courtesy of Medical Chemical Corporation).

Molecular Changes Associated with Treating Lymphatic Filariasis

Lymphatic filariasis (LF) is a disabling neglected tropical disease that is caused by the mosquito-borne filarial parasites Wuchereria bancrofti, Brugia malayi and B. timori. Adult worms live in the human host’s lymphatic system and release larval parasites (microfilariae or Mf) that circulate in the blood. More...
09 Oct 2019
Image: Rift Valley Fever (RVF) lateral flow immunochromatographic (LFT) strip test for the detection of RVF infection using the two selected monoclonal antibodies (Photo courtesy of University of Montpellier).

Immunochromatographic Strip Test Developed for Rift Valley Fever

Rift Valley fever (RVF) is an emerging mosquito-borne disease that affects a wide range of animals and human beings in Africa and the Arabian Peninsula. A rapid and specific test for RVF diagnosis at the site of a suspected outbreak is crucial for the implementation of control measures. More...
03 Oct 2019
Image: Scanning electron micrograph of a pair of Schistosoma mansoni (Photo courtesy of the Davies Laboratory Uniformed Services University).

RT-PCR Evaluated for Diagnosis of Imported Schistosomiasis

Schistosomiasis is one of the most important human parasitic neglected tropical diseases. It is a major source of morbidity and mortality in Africa but also in South America, the Caribbean, the Middle East, and Asia. More...
03 Oct 2019
Image: The Navios Flow Cytometer offers a solution for advanced cytometry applications with workflows for high throughput laboratories (Photo courtesy of Beckman Coulter).

Early Diagnosis of Tularemia Accomplished by Flow Cytometry

Tularemia is a zoonotic disease that occurs in the Northern Hemisphere and is caused by Francisella tularensis. In Europe, more than 500 cases are reported annually and Turkey and the USA also have substantial disease burdens. More...
02 Oct 2019
Image: Representative test strips of the two-color LFA. Distinct colors were observed at the test lines, corresponding to a type of antigen, such as a blue test lines for pLDH detection only (Photo courtesy of Cornell University).

Multiplexed Immunoassay System Differentiates Malaria Species

Over 40% of world’s population live in malaria-endemic areas, and malaria is found in more than 100 countries in Africa, Latin America, the Caribbean, Southeast Asia, the Eastern Mediterranean, the Western Pacific, and parts of Europe. More...
02 Oct 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.