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Microbiology

Image: Bacteria in the gut are pulled into the helical channels by an osmotic “pump” generated by a calcium salt-filled chamber within the pill (Photo courtesy of Nano Lab, Tufts University).

Novel Diagnostic Device Profiles Population of Gut Microbiome

Researchers used a three-dimensional (3D) printer to manufacture a novel pill-like diagnostic tool capable of profiling the bacterial species comprising the gut microbiome in the critical area between the stomach and the colon. More...
05 Aug 2019
Image: The Applied Biosystems Veriti HID 96-Well Thermal Cycler (Photo courtesy of Thermo Fisher Scientific).

Multiplex PCR Developed for Neglected Infectious Diseases

Scrub typhus, murine typhus, and leptospirosis are diagnosed as acute undifferentiated febrile illness. Diagnostic tests for these diseases depend on antibody detection. However, antibody detection is still limited by its tendency to return negative results during the early phase of these diseases. More...
01 Aug 2019
Image: A photomicrograph of Gram stain of toxigenic Clostridioides difficile from a stool sample (Photo courtesy of the University of Washington).

Clostridioides difficile Contamination Uncovered in Clinical Lab

Clostridioides (formerly Clostridium) difficile infection is one of the most common hospital-acquired (nosocomial) infections and is an increasingly frequent cause of morbidity and mortality among older adult hospitalized patients. C. difficile is a spore-forming, Gram-positive anaerobic bacillus that produces two exotoxins: toxin A and toxin B. More...
01 Aug 2019
Image: The Xpert MRSA/SA SSTI assay detects methicillin-resistant S. aureus (MRSA) & S. aureus (SA) in skin and soft tissue infections in less than one hour (Photo courtesy of Cepheid).

Rapid Diagnostic Panel Used for Pediatric Musculoskeletal Infections

The findings from a retrospective analysis suggested that the use of a rapid musculoskeletal diagnostic panel, or MDP, could have shortened the time it took to identify the cause of infection, provide appropriate antibiotics and reduce the length of stay for children in hospital. More...
31 Jul 2019
Image: Thin blood smear showing a Plasmodium falciparum gametocyte (single arrow) and a schizont of P. vivax (double arrow) from a mixed infection case (Photo courtesy of Sulekha Bhat et al).

Submicroscopic Malaria Prevalence Reported in Immigrants

Malaria remains the most important parasitic infection for humans, causing about 2,000 deaths per day, especially in African children younger than five years old. The importance of submicroscopic malaria infections in high-transmission areas could contribute to maintain the parasite cycle. More...
30 Jul 2019
Image: A Giemsa-stained, thin film blood smear that shows the presence of numerous of ring-form, Plasmodium falciparum trophozoites, with some infected red blood cells (RBCs) harboring multiple organisms (Photo courtesy of Steve Glenn/CDC).

Gene Deletions Affect Rapid Diagnostic Tests for Malaria

Prompt and accurate diagnosis of malaria is crucial for malaria case-management and control and elimination programs. While malaria diagnosis was historically based on symptoms alone, guidelines state that parasite-based diagnosis of malaria should be confirmed before treatment is given. More...
25 Jul 2019
Image: The Multiskan GO microplate spectrophotometer (Photo courtesy of Thermo Fisher Scientific).

Methods Evaluated to Detect Asymptomatic Visceral Leishmaniasis

Visceral leishmaniasis (VL) is caused by Leishmania infantum [synonymous L. chagasi] in the New World or L. donovani in the Old World, VL can be classified as an anthroponotic or zoonotic disease because it is transmitted between humans and others mammals, such as dogs. More...
24 Jul 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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