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Immunology

Image: The Lumipulse G CK-MB immunoassay, an aid in the diagnosis of acute myocardial infarction, being prepared to run on a LUMIPULSE G1200 instrument (Photo courtesy of Fujirebio Europe).

CK-MB Assay Used to Diagnose Acute Myocardial Infarction

Creatine Kinase (CK) is an enzyme found in high amounts in muscle tissue due to its role in muscle contraction. CK-MB is found mainly in cardiac muscle, where it comprises 15%-40% of the total CK activity, with the remainder being CK-MM. More...
07 Nov 2017
Image: Dipstick tests for dengue (left) and Zika (right) accurately identify the presence of Zika virus protein in a sample (Photo courtesy of Massachusetts Institute of Technology).

Novel Immunochromatographic Method Rapidly Identifies Flaviviruses

The recent Zika virus (ZIKV) outbreak demonstrates that cost-effective clinical diagnostics are urgently needed to detect and distinguish viral infections to improve patient care. Unlike dengue virus (DENV), ZIKV infections during pregnancy correlate with severe birth defects, including microcephaly and neurological disorders. More...
01 Nov 2017
Image: Box‐and‐whisker plot comparisons between nonsurvivors (n=8) and survivors (n=35) by: (A) body mass index, (B) maximal inspiratory pressure, and (C) N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) (Photo courtesy of Cheeran D et al, 2017, Journal of the American Heart Association).

Risk Factors Identified for Duchenne Muscular Dystrophy-Associated Cardiomyopathy

Researchers have now identified important factors associated with death, thus highlighting a high‐risk DMD population with a worse cardiovascular and overall prognosis. More...
30 Oct 2017
Image: Whole genome genotyping arrays are an important tool for discovering variants that contribute to human disease (Photo courtesy of Megan Smolenyak, MBA).

New Genetic Risk Factors Identified for Peanut Allergy

Peanut allergy develops in early life and is rarely outgrown. Roughly 1% of Canadian adults and between 2% and 3% of Canadian children are affected, and the symptoms can be severe and even life threatening. More...
25 Oct 2017
Image: A positive pregnancy test; Women with test results indicating low ovarian reserve were no less likely to conceive within six or 12 months of attempts than women whose laboratory tests did not point to a limited egg supply (Photo courtesy of News Health Advisor).

Ovarian Reserve Tests Prove Poor Predictors of Fertility

Tests that measure a woman’s “ovarian reserve” to estimate how many more years of fertility she has have grown increasingly popular, yet despite the lack of evidence of their utility, biomarkers of ovarian reserve are being promoted as potential markers of reproductive potential. More...
24 Oct 2017
Image: The QuantiFERON-TB Gold Plus (QFT-Plus) is the fourth generation of the leading blood test for tuberculosis (Photo courtesy of Qiagen).

Improved Blood Test for TB Launched

Tuberculosis (TB) is a contagious bacterial infection spread primarily by coughing of patients with the active pulmonary form of the disease. In 2015, it was estimated that there were 10.4 million new cases of active TB worldwide and 1.8 million deaths from TB. More...
18 Oct 2017
Image: the ImmunoXpert is a pioneering in-vitro diagnostic test that accurately distinguishes between bacterial and viral infections based on the patient’s immune response (Photo courtesy of MeMed).

Blood Test Accurately Distinguishes Bacterial and Viral Infections

The difficulty in properly distinguishing between viral and bacterial infections results in one of two outcomes. Either there is an overuse of antibiotics, which results in a rise in antibiotic resistance; or antibiotics are under-prescribed, which hurts those patients who have a legitimate need. More...
11 Oct 2017
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.