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BioResearch

Image: When the enzyme DYRK3 is inhibited, mitotic defects are resulting (red: droplets, green: spindle, blue: DNA) (Photo courtesy of Arpan Rai, University of Zurich).

Mechanism Regulates Organelle Distribution during Cell Division

A team of Swiss cell biologists has discovered how cells maintain the integrity and distribution of cytoplasmic organelles during and following the process of cell division. More...
24 Jul 2018
Image: The eye of a zebrafish embryo deficient in NADPH oxidase 2 has an enlarged ganglion cell layer (green) and altered innervation of the brain, which leads to problems with signaling between the eyes and the brain (Photo courtesy of Dr. Daniel Suter, Purdue University).

Model Defines Role of Reactive Oxygen Species in Neural System Development

Using a mutant zebrafish model, a team researching development of the neural system has found a molecular mechanism linking reactive oxygen species to growth of the retina and its associated nerves. More...
23 Jul 2018
Image: A micrograph of a teratoma showing tissue from all three germ layers: mesoderm (immature cartilage - left-upper), endoderm (gastrointestinal glands - center-bottom) and ectoderm (epidermis - right) (Photo courtesy of Wikimedia Commons).

Teratomas Offer Source for Rebuilding Damaged Tissues

Muscle stem cells, which were derived from benign teratoma tumors, were found to demonstrate exceptional potential as starting material for rebuilding and maintaining damaged muscle tissues. More...
19 Jul 2018
Image: This photomicrograph reveals the histopathology in an acute case of gonococcal urethritis using Gram-stain technique. This slide demonstrates the non-random distribution of gonococci among polymorphonuclear neutrophils. Note that there are both intracellular and extracellular bacteria in the field of view (Photo courtesy of the CDC).

Novel Bacterial Inhibitor Blocks Lysozyme Activity in Model

A team of molecular microbiologists has identified a mechanism by which certain bacteria – in particular the Gram-negative pathogen Neisseria gonorrhoeae – avoid lysozyme destruction. More...
18 Jul 2018
Image: A histopathology of urothelial carcinoma of the urinary bladder (Photo courtesy of Wikimedia Commons).

MicroRNA Biomarker Identified for Bladder Cancers

Cancer researchers have identified a microRNA that acts as a prognostic biomarker of p53-like bladder cancers. More...
17 Jul 2018
Image: The left-side group of mice is a control - with neither the gene editing RNA, nor the BOC switch. The next group has BOC but no RNA, and the third has the RNA, but no BOC to switch it on. The final group on the right has the gene editing machinery and the BOC switch. BOC activates the switch and the pups are born without green fluorescence (Photo courtesy of Dr. Tony Perry, University of Bath).

Genetic Code Expansion Used to Establish Biological Control Mechanism

A team of genomics researchers has described the development of a novel biological switching mechanism that enables control over the activity of the CRISPR/Cas9 gene-editing tool. More...
16 Jul 2018
Image: MicroRNA 142, in green, shown in neurons in the brain. The molecule may represent a potential biomarker to diagnosis or predict Tau protein-linked dementia (Photo courtesy of Dr. Hui-Chen Lu, Indiana University).

MicroRNAs Changes Precede Symptoms in Tauopathies

Neurodegenerative researchers have tested the possibility of using measurement of specific microRNAs for the early diagnosis of tauopathies, long before appearance of any symptoms. More...
12 Jul 2018
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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