BioResearch
![Image: A scanning electron micrograph (SEM) of a human a T-cell from the immune system of a healthy donor (Photo courtesy of the [U.S.] National Institutes of Health).](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2018-04-25/GMS-078.jpg "Image: A scanning electron micrograph (SEM) of a human a T-cell from the immune system of a healthy donor (Photo courtesy of the [U.S.] National Institutes of Health).")
Vaccine Induces Protective Immune Response in Mouse Model
Vaccination of mice with a peptide derived from the apoB protein component of low density lipoprotein (LDL) stimulated increased production of regulatory T-cells (Tregs) and reduction in number and size of atherosclerotic lesions. More...25 Apr 2018
Artificial RNAs Increase Precision of Gene-Editing System
Incorporation of next-generation bridged nucleic acids at specific locations in CRISPR-RNAs (crRNAs) broadly reduces off-target DNA cleavage by Cas9 - a major drawback slowing the development of genome editing clinical applications - in vitro and in cells by several orders of magnitude. More...24 Apr 2018
Inhibiting Fibronectin Polymerization Reduces Injury to Cardiac Muscle
Working with a mouse model of human heart disease, researchers showed that interfering with fibronectin (FN) polymerization or its genetic deletion in fibroblasts would attenuate cardiac myofibroblasts (MF), fibrosis, and improve cardiac function following heart attack related injury. More...24 Apr 2018
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In Other News
Compound Demonstrates Potential as Broad-Spectrum Antiviral Drug
Stroke Genetics Study Triples Number of Known Risk Loci
Critical Brain Cell Repair Gene Identified in Study
Antibody Clears Amyloid Plaques in Mouse Model
Role of RNA Methylation Defined in Drug Resistance by Leukemia Cells
Less Toxic Drugs May Replace Current Chemotherapeutic Agents
Pecan-Enriched Diet Protects against CV Disease and Diabetes
Review Article Summarizes Progress Towards Drug Development
Nanospear Technology Developed for Directed Gene Therapy
Innovations Increase Sensitivity of CTC Detection
Novel Gene-Editing Tool Specifically Modifies RNA
Virtual Model Set to Boost Drug Development Efforts
Genetic Link Found for Physical and Psychological Disorders
Hydrogel Developed for Controlled Release of Immunotherapeutic Drugs
Microscopy Technique Monitors Biomarkers of Subcellular Alterations
Biomimetic Nanoparticles Prove Effective for Biotherapeutic Drug Transport
Lung Progenitor Cells Enable Culture of 3D Organoids for Studies
New Cancer Treatments Aimed at Preventing Drug Resistance
Environmental Influences Important in Determining Microbiome Composition
Naturally Occurring CRISPR/Cas9 Cuts DNA and RNA
Cancer Progression Linked to Activity of Exosomes and Exomeres
Oncogene Used as Drug Transporter to Block Tumor Growth
Novel Hydrogel Slows Tumor Growth and Prevents Recurrence
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.