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BioResearch

Image: Structure of the C-terminal helical repeat domain of eukaryotic elongation factor 2 kinase (EEF2K) (Photo courtesy of the U.S. National Center for Biotechnology Information).

Inactivation of Enzyme Corrects Alzheimer's Disease Defects

A team of neurodegenerative disease researchers identified a molecular mechanism that impedes protein synthesis and may contribute to the loss of memory and synaptic plasticity that characterizes Alzheimer's disease (AD). More...
28 Feb 2019
Image: Platelet decoys (pink), unlike normal platelets, are not activated by collagen fibers (gray), making them an attractive option for antithrombotic and cancer treatment (Photo courtesy of Harvard University).

Modified Platelets Reduce Risk of Blood Clots and Prevent Metastasis

A promising method for reducing the risk of blood clots and preventing tumor metastasis is based on treatment with blood platelets that have been modified to be incapable of activation and aggregation while retaining their functional binding properties. More...
27 Feb 2019
Image: Researchers found that cells behave differently in this three-dimensional (3D) soft tissue environment than on two-dimensional (2D) plastic or glass surfaces (Photo courtesy of the University of Minnesota).

Bioprinting Studies How Cancer Cells Grow and Spread

Novel use of a three-dimensional (3D) bioprinting technique has created new ways to study how cancer cells grow and spread. More...
26 Feb 2019
Image: The new AggTag method allows researchers to see the previously undetectable but potentially disease-causing intermediate forms of proteins as they misfold. The method uses fluorescence to simultaneously detect two different proteins (red, green) within the cell (blue) (Photo courtesy of the Zhang Laboratory, Pennsylvania State University).

Fluorescence-Based Method Detects Misfolded Proteins in Cells

A new fluorescence-based method is expected to boost studies on toxic insoluble proteins by detecting aggregation of two proteins in live cells simultaneously. More...
25 Feb 2019
Image: An artistic representation of circulating tumor cells traveling in the bloodstream escorted by neutrophils. Through this interaction, neutrophils are able to enhance the metastatic ability of circulating tumor cells (Photo courtesy of the University of Basel).

Blocking CTCs and Neutrophils Could Prevent Cancer Metastasis

A mechanism has been proposed that explains why the association of circulating tumor cells (CTCs) and immune neutrophils enhances the ability of the cancer cells to form metastases. More...
21 Feb 2019
Image: A simple treatment using four small molecules converts human astrocytes - a common type of cells in the nervous system - into new neurons, which develop complex structures after four months (Photo courtesy of the Gong Chen Laboratory, Pennsylvania State University).

Cocktail of Molecules Induces Astrocytes to Transform into Neurons

A team of neurobiological researchers developed a simple recipe requiring only three or four small molecules to convert human fetal astrocytes into neurons. More...
20 Feb 2019
Image: The diagram illustrates the path of action of a new imaging and platelet targeting chemotherapy agent for the early detection and treatment of cancers (Photo courtesy of the Baker Heart and Diabetes Institute).

Anti-Cancer Treatment Targets Activated Platelets in Tumor Microenvironment

A novel chemotherapeutic agent transport system is based on the binding of an antibody-drug conjugate specifically directed to a surface protein on activated platelets in the tumor microenvironment. More...
19 Feb 2019
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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