BioResearch
Subpopulation of Fibroblasts Drives Breast Tumor Development
Breast tumors with reduced levels of the enzyme platelet-derived growth factor alpha (PDGFRalpha), which is caused by recruitment of a distinct subpopulation of bone marrow-derived cancer-associated fibroblasts, have been linked to a worse prognosis for the patient. More...03 Dec 2018
Protein Crystals Used to Prepare Cellular Drug Delivery Nanotubes
A team of Japanese biomolecular engineers used scaffolds of cross-linked protein crystals to prepare nanotubes, which are structures that can serve as the basis for minute delivery systems for drugs and other substances. More...28 Nov 2018
Modified Nanoparticle Drug Carriers Target Solid Tumors in Model
Cancer researchers used novel targeted nanoparticles to transport drugs to solid tumors when the absence of a persistent EPR (enhanced permeability and retention) effect, acted as an access barrier negatively affected the effectiveness of drug delivery. More...27 Nov 2018
Linked Antibodies Provide Universal Protection from Influenza Infection
A potential universal vaccine that would protect individuals from infection by all strains of influenza virus is based on multidomain antibodies that were fabricated by combining selected llama single-domain antibodies. More...22 Nov 2018
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In Other News
Nanoneedle Bio-patch Provides Minimally Invasive Drug Delivery
Mutation in p53 Suppressor Gene Drives Tumor Development
Biodegradable Nanoscaffolds Improve Chances for Stem Cell Therapies
In vivo CRISPR/Cas9 Therapy Prevents Arrhythmias in Model
Mechanism Explains Why Damaged DNA Accumulates in ALS Neurons
Immune Sensitivity Hampers Clinical Applications of CRISPR/Cas9
Proposed Treatment Aims to Re-Sensitize Cancer Cells
Tumor-Secreted Ligands Induce Fibroblast Behavior
Novel CDK9 Inhibitor Prevents Cancer Growth
Dysregulation of Retinoic Acid Signaling in Stem Cells Spurs Tumor Growth
Functional 3D Neural Network Models Generated from Stem Cells
Antisense DNA Drug Cures Prostate Cancer in Model
Researchers Aim to Reduce Variability of Gene Therapy Vectors
Candidate Anticancer Drug Effectively Treats Drug-resistant Pancreatic Cancer
Gene Mutation Reduces Glucose Uptake and Premature Mortality
Long Non-Coding RNA Identified Modulates Synaptic Morphology and Function
Elevated Collagen XIII Levels Linked to Breast Cancer Metastasis
Gene Editing Used to Mimic Dysfunctional Neurodegenerative Calcium Transport
Screening Technique Finds Endothelial Cells Targeted by Nanoparticles
Research Determines Why Different Cancers Display Similar Profiles
Molecular Scaffolds Promise Drug Synthesis in Breast Cancer Treatment
Targeted Delivery of Resveratrol Prevents Lung Cancer in Model
Genetically Engineered Zika Virus Slows Tumor Growth in Model
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.