New Imaging Workstation Provides Superior Sensitivity for Gel/Blot Analyses
|
By LabMedica International staff writers Posted on 08 Jan 2013 |

Image: The PXi Multiapplication gel and blot imaging system (Photo courtesy of Syngene).
A new high resolution, multiapplication imaging system includes a wide range of lighting options, a new-generation camera, and specialized software, enabling exceptional sensitivity for analysis of gels and blots.
The PXi gel and blot imaging system from Syngene (Frederick, MD, USA) is a sophisticated and easy-to-use, compact workstation for the capture and image analysis of chemiluminescent and fluorescent blots, fluorescent and IR gels, visible gels and blots, and even 2D gels. PXi is available in three versions - with a 4, 6, or 8 million pixel high performance camera and suitable lens that results in the system having superior sensitivity such that even faint gels, chemiluminescence blots, and faint fluorescent bands can be imaged. In addition, the cameras are cooled to enable longer exposures, which can be a necessity for chemiluminescence and for some fluorescence applications.
The high performance range of PXi has been designed to provide a high level of control and to excel at a wide range of applications. The system has options for advanced automation or manual control. A number of lighting options can be utilized including plug and play LED modules for Red, Green, Blue and IR light. These novel lighting systems provides the user with the ability to perform colored fluorescent, multiplex, and colorimetric imaging. The new UltraSlim blue LED transilluminator provides a solution for imaging “safe dyes.” An integral 7-position filter wheel can accommodate a wide range of Syngene filters. PXi is controlled by the GeneSys acquisition and capture software. Using its database, GeneSys can automatically configure PXi to capture any type of image.
Related Links:
Syngene
The PXi gel and blot imaging system from Syngene (Frederick, MD, USA) is a sophisticated and easy-to-use, compact workstation for the capture and image analysis of chemiluminescent and fluorescent blots, fluorescent and IR gels, visible gels and blots, and even 2D gels. PXi is available in three versions - with a 4, 6, or 8 million pixel high performance camera and suitable lens that results in the system having superior sensitivity such that even faint gels, chemiluminescence blots, and faint fluorescent bands can be imaged. In addition, the cameras are cooled to enable longer exposures, which can be a necessity for chemiluminescence and for some fluorescence applications.
The high performance range of PXi has been designed to provide a high level of control and to excel at a wide range of applications. The system has options for advanced automation or manual control. A number of lighting options can be utilized including plug and play LED modules for Red, Green, Blue and IR light. These novel lighting systems provides the user with the ability to perform colored fluorescent, multiplex, and colorimetric imaging. The new UltraSlim blue LED transilluminator provides a solution for imaging “safe dyes.” An integral 7-position filter wheel can accommodate a wide range of Syngene filters. PXi is controlled by the GeneSys acquisition and capture software. Using its database, GeneSys can automatically configure PXi to capture any type of image.
Related Links:
Syngene
Latest BioResearch News
- Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns
- Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma
- New Method Simplifies Preparation of Tumor Genomic DNA Libraries
- New Tool Developed for Diagnosis of Chronic HBV Infection
- Panel of Genetic Loci Accurately Predicts Risk of Developing Gout
- Disrupted TGFB Signaling Linked to Increased Cancer-Related Bacteria
- Gene Fusion Protein Proposed as Prostate Cancer Biomarker
- NIV Test to Diagnose and Monitor Vascular Complications in Diabetes
- Semen Exosome MicroRNA Proves Biomarker for Prostate Cancer
- Genetic Loci Link Plasma Lipid Levels to CVD Risk
- Newly Identified Gene Network Aids in Early Diagnosis of Autism Spectrum Disorder
- Link Confirmed between Living in Poverty and Developing Diseases
- Genomic Study Identifies Kidney Disease Loci in Type I Diabetes Patients
- Liquid Biopsy More Effective for Analyzing Tumor Drug Resistance Mutations
- New Liquid Biopsy Assay Reveals Host-Pathogen Interactions
- Method Developed for Enriching Trophoblast Population in Samples
Channels
Clinical Chemistry
view channel
VOCs Show Promise for Early Multi-Cancer Detection
Early cancer detection is critical to improving survival rates, but most current screening methods focus on individual cancer types and often involve invasive procedures. This makes it difficult to identify... Read more
Portable Raman Spectroscopy Offers Cost-Effective Kidney Disease Diagnosis at POC
Kidney disease is typically diagnosed through blood or urine tests, often when patients present with symptoms such as blood in urine, shortness of breath, or weight loss. While these tests are common,... Read moreMolecular Diagnostics
view channel
Blood Test Uses Cell-Free DNA to Detect ALS Faster and More Accurately
Diagnosing amyotrophic lateral sclerosis (ALS), a rare and fatal neurodegenerative disease, is often a lengthy and complex process, as its early symptoms can mimic other neurological conditions.... Read more
Multi-Cancer Early Detection Blood Test Increases Cancer Detection
Cancer is the second leading cause of death worldwide as most deadly cancers are found too late. Approximately 70% of cancer deaths come from cancers that do not have standard-of-care screening and are... Read moreHematology
view channel
Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage
Postpartum hemorrhage, severe bleeding after childbirth, remains one of the leading causes of maternal mortality worldwide, yet many of these deaths are preventable. Standard care can be hindered by delays... Read more
Pioneering Model Measures Radiation Exposure in Blood for Precise Cancer Treatments
Scientists have long focused on protecting organs near tumors during radiotherapy, but blood — a vital, circulating tissue — has largely been excluded from dose calculations. Each blood cell passing through... Read more
Platelets Could Improve Early and Minimally Invasive Detection of Cancer
Platelets are widely recognized for their role in blood clotting and scab formation, but they also play a crucial role in immune defense by detecting pathogens and recruiting immune cells.... Read more
Portable and Disposable Device Obtains Platelet-Rich Plasma Without Complex Equipment
Platelet-rich plasma (PRP) plays a crucial role in regenerative medicine due to its ability to accelerate healing and repair tissue. However, obtaining PRP traditionally requires expensive centrifugation... Read moreImmunology
view channel
Molecular Microscope Diagnostic System Assesses Lung Transplant Rejection
Lung transplant recipients face a significant risk of rejection and often require routine biopsies to monitor graft health, yet assessing the same biopsy sample can be highly inconsistent among pathologists.... Read more
Blood Test Tracks Treatment Resistance in High-Grade Serous Ovarian Cancer
High-grade serous ovarian cancer (HGSOC) is often diagnosed at an advanced stage because it spreads microscopically throughout the abdomen, and although initial surgery and chemotherapy can work, most... Read more
Luminescent Probe Measures Immune Cell Activity in Real Time
The human immune system plays a vital role in defending against disease, but its activity must be precisely monitored to ensure effective treatment in cancer therapy, autoimmune disorders, and organ transplants.... Read more
Blood-Based Immune Cell Signatures Could Guide Treatment Decisions for Critically Ill Patients
When a patient enters the emergency department in critical condition, clinicians must rapidly decide whether the patient has an infection, whether it is bacterial or viral, and whether immediate treatment... Read moreMicrobiology
view channel
Fast Noninvasive Bedside Test Uses Sugar Fingerprint to Detect Fungal Infections
Candida bloodstream infections are a growing global health threat, causing an estimated 6 million cases and 3.8 million deaths annually. Hospitals are particularly vulnerable, as weakened patients after... Read more
Rapid Sepsis Diagnostic Device to Enable Personalized Critical Care for ICU Patients
Sepsis is a life-threatening condition that occurs when the body’s response to infection spirals out of control, damaging organs and leading to critical illness. Patients often arrive at intensive care... Read morePathology
view channel
AI Improves Cervical Cancer Screening in Low-Resource Settings
Access to cervical cancer screening in low- and middle-income countries remains limited, leaving many women without early detection for this life-threatening disease. The lack of access to laboratories,... Read more
New Multi-Omics Tool Illuminates Cancer Progression
Tracking how cancers evolve into more aggressive and therapy-resistant forms has long been a challenge for researchers. Many current tools can only capture limited genetic information from tumor samples,... Read moreTechnology
view channel
Viral Biosensor Test Simultaneously Detects Hepatitis and HIV
Globally, over 300 million people live with Hepatitis B and C, and 40 million with HIV, according to WHO estimates. Diagnosing bloodborne viruses such as HIV and Hepatitis B and C remains challenging in... Read more
Acoustofluidic Device to Transform Point-Of-Care sEV-Based Diagnostics
Rapid and sensitive detection of small extracellular vesicles (sEVs)—key biomarkers in cancer and organ health monitoring—remains challenging due to the need for multiple preprocessing steps and bulky... Read moreIndustry
view channel
Advanced Instruments Merged Under Nova Biomedical Name
Advanced Instruments (Norwood, MA, USA) and Nova Biomedical (Waltham, MA, USA) are now officially doing business under a single, unified brand. This transformation is expected to deliver greater value... Read more







