LabMedica

Download Mobile App
Recent News Expo Clinical Chem. Molecular Diagnostics Hematology Immunology Microbiology Pathology Technology Industry Focus

Meridian Bioscience Launches Novel Ready-to-Use, Air-Dryable RT-qPCR Mix for COVID-19 Assay Development

By LabMedica International staff writers
Posted on 04 Dec 2020
Print article
Illustration
Illustration
A newly-launched novel air-dryable RT-qPCR mix aims to further decrease costs and simplify workflows for manufacturers of COVID-19 molecular tests.

Meridian Bioscience, Inc. (Cincinnati, OH, USA) has launched an Air-Dryable RT-qPCR Mix, driving innovation in the development of molecular tests with ambient temperature stability. The specialized master mix is designed for air-drying, a cost-effective and easier alternative to lyophilization.

While molecular diagnostic tests are progressively moving towards a dried-down format, there are technical challenges in developing lyophilization-compatible mixes that require lengthy optimization and expensive lyophilization equipment. Meridian has developed a ready-to-use, air-dryable RT-qPCR mix to meet the growing demand within the molecular diagnostics industry for an easier and more cost-effective method of drying RNA assays.

Meridian’s Air-Dryable RT-qPCR Mix has been designed to simplify development, manufacturing and storage of molecular assays while delivering fast detection of RNA targets, an ideal solution for COVID-19 assay development. Its one-tube format chemistry containing all reagents necessary for a RT-qPCR, including magnesium, dNTP and reverse transcriptase, not only shortens assay optimization but is also compatible with air-drying protocols. The new mix shows exceptionally high performance in both singleplex and multiplex reactions following rehydration, making it ideally suited for a wide range of instruments from automated high-throughput platforms to point-of-care devices.

“Over the last 12 months, we have seen a significant increase in demand for our Lyo-Ready RT-qPCR mixes; however, not all our customers have the expertise in-house to lyophilize,” said Florent Chang-Pi-Hin, PhD, Senior Director of Research and Development at Meridian Bioscience. “Building on the launch of our Air-Dryable qPCR Mix earlier this year, our new Air-Dryable RT-qPCR Mix represents a perfect solution for the development of ambient temperature stable assays for RNA targets, which is so important today with the global fight against SARS-CoV-2.”

Related Links:
Meridian Bioscience, Inc.

Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
Magnetic Bead Separation Modules
MAG and HEATMAG
POCT Fluorescent Immunoassay Analyzer
FIA Go
Gold Member
SARS‑CoV‑2/Flu A/Flu B/RSV Sample-To-Answer Test
SARS‑CoV‑2/Flu A/Flu B/RSV Cartridge (CE-IVD)

Print article

Channels

Clinical Chemistry

view channel
Image: The 3D printed miniature ionizer is a key component of a mass spectrometer (Photo courtesy of MIT)

3D Printed Point-Of-Care Mass Spectrometer Outperforms State-Of-The-Art Models

Mass spectrometry is a precise technique for identifying the chemical components of a sample and has significant potential for monitoring chronic illness health states, such as measuring hormone levels... Read more

Hematology

view channel
Image: The CAPILLARYS 3 DBS devices have received U.S. FDA 510(k) clearance (Photo courtesy of Sebia)

Next Generation Instrument Screens for Hemoglobin Disorders in Newborns

Hemoglobinopathies, the most widespread inherited conditions globally, affect about 7% of the population as carriers, with 2.7% of newborns being born with these conditions. The spectrum of clinical manifestations... Read more

Immunology

view channel
Image: The AI predictive model identifies the most potent cancer killing immune cells for use in immunotherapies (Photo courtesy of Shutterstock)

AI Predicts Tumor-Killing Cells with High Accuracy

Cellular immunotherapy involves extracting immune cells from a patient's tumor, potentially enhancing their cancer-fighting capabilities through engineering, and then expanding and reintroducing them into the body.... Read more

Microbiology

view channel
Image: The T-SPOT.TB test is now paired with the Auto-Pure 2400 liquid handling platform for accurate TB testing (Photo courtesy of Shutterstock)

Integrated Solution Ushers New Era of Automated Tuberculosis Testing

Tuberculosis (TB) is responsible for 1.3 million deaths every year, positioning it as one of the top killers globally due to a single infectious agent. In 2022, around 10.6 million people were diagnosed... Read more