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Immunology

Image: A scanning electron micrograph (SEM) of lung cancer cells (Photo courtesy of Cancer Research UK).

Immune Relationship to Lung Tumor Evolution Characterized

Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC). NSCLC accounts for about 85% of all lung cancers. As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small cell carcinoma. More...
04 Apr 2019
Image: The HiSeq 2500 System is a powerful high-throughput sequencing system (Photo courtesy of Illumina).

Preterm Birth Clues Identified in Cervicovaginal Microbiome

Failure to predict and understand the causes of preterm birth, the leading cause of neonatal morbidity and mortality, have limited effective interventions and therapeutics. Preterm birth (PTB) is defined as birth before 37 completed weeks of gestation and is the leading cause of death in neonates and children under the age of 5. More...
03 Apr 2019
Image: The UniCel DxI 800 access immunoassay platform (Photo courtesy of Beckman Coulter).

Blood Test to Diagnose Heart Attacks Can Be Misleading

The use of increasingly sensitive troponin assays for excluding or diagnosing acute myocardial infarction has become universal. A diagnosis of acute myocardial infarction is defined, in the context of an appropriate clinical presentation, by a rise or fall in cardiac troponin concentration, now the gold standard biomarker. More...
27 Mar 2019
Image: The ZymoBIOMICS DNA Mini Kit is designed for purifying DNA from any sample input that is immediately ready for microbiome or metagenome analyses (Photo courtesy of Zymo Research).

Oral Bacteria Linked to More Aggressive Tumors

Pancreatic cystic neoplasms (PCN) are increasingly detected in the general population. They comprise a clinically challenging entity with potential to progress to invasive cancer. The disease is often discovered late, which means that in most cases the prognosis is poor. More...
26 Mar 2019
Image: The Urisys 2400 urine analyzer (Photo courtesy of Roche Diagnostics).

Urinary KIM-1 Concentration Interpreted in Detecting AKI

Kidney injury molecule-1 (KIM-1) has been identified as a biomarker for the assessment of nephropathy in various chronic kidney diseases (CKD). Extensive KIM-1 expression occurs in proximal tubule cells in patients with confirmed acute tubular necrosis. More...
25 Mar 2019
Image: The cobas e 602 integrates immunoassay and clinical chemistry testing on a single platform (Photo courtesy of Roche).

Efficacy Investigated for Electrochemiluminescence Immunoassay

Syphilis caused by Treponema pallidum is a chronic bacterial infection. T. pallidum cannot be cultured in vitro, and new molecular tests for syphilis are unlikely to replace serology in the short term because they are fairly expensive and require sophisticated equipment. More...
20 Mar 2019
Image: The FACSCanto II triple-laser flow cytometer (Photo courtesy of BD Biosciences).

Recurrent Miscarriage Patients Show Activated Immune System

Recurrent loss of pregnancy is an important reproductive health issue, affecting 2% to 5% of couples. Almost half of the cases remain unexplained and are treated empirically, using progesterone supplementation, anticoagulation, and/or immunomodulatory approaches. More...
19 Mar 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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