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Immunology

Image: A scanning electron photomicrograph of Candida albicans yeast cells (Photo courtesy of Science Photo Library).

Immune-Related Gene Implicated in Chronic Candida Infection Risk

Candida vaginitis is a frequent clinical diagnosis with up to 8% of women experiencing recurrent vulvovaginal candidiasis (RVVC) globally. RVVC is characterized by at least three episodes per year. More...
26 Jun 2019
Image: Lupus Erythematosus (LE) Cells are neutrophils that have engulfed lymphocyte nuclei coated with and denatured by antibody to nucleoprotein (Photo courtesy of Dr. Moustafa Abdou).

Cardiovascular Risk Biomarkers Found for JSLE Patients

Systemic lupus erythematosus is an autoimmune disease typically affecting women between the ages of 15 and 50, and symptoms flare up unpredictably. Approximately 20% of cases begin during childhood and in these patients the disease is suggested to be more severe. More...
25 Jun 2019
The enzyme-linked immunosorbent assay for estradiol (E2) (Photo courtesy of Calbiotech).

Higher Estrogen Levels Linked to Severe Disease in Scleroderma

 Systemic sclerosis (SSc) is an autoimmune, connective tissue disease of unknown etiology characterized by immune system dysregulation and excessive extracellular matrix (ECM) synthesis. As in most autoimmune diseases, there is a female predominance in SSc with a female to male ratio of 3:1, which increases to 9:1 during childbearing years. More...
19 Jun 2019
The Prolisa C. difficile GDH EIA is a microwell assay for the qualitative detection of Clostridium difficile glutamate dehydrogenase (GDH) in fecal specimens. The test is intended for use as an aid in the diagnosis of C. difficile infections (Photo courtesy of Pro-Lab Diagnostics).

NA Amplification Tests for Clostridium Diagnosis Reviewed

 Clostridioides (Clostridium) difficile infection (CDI) is the leading cause of health care-associated infections in the USA. It accounts for 15% to 25% of health care-associated diarrhea cases in all health care settings, with 453,000 documented cases of CDI and 29,000 deaths in the USA in 2015. More...
19 Jun 2019
Image: The NimbleGen MS 200 CGH LOH microarray detection scanner (Photo courtesy of Roche).

Kidney Transplant Rejection Linked to New Mismatch Locus

Approximately 20% of the kidney waiting list in the USA consists of candidates whose allografts have failed. Acute rejection is one of the strongest predictors of decreased allograft survival. More...
13 Jun 2019
Image: The LSRFortessa cell analyzer offers the ultimate in choice for flow cytometry, providing power, performance, and consistency (Photo courtesy of BD Biosciences).

Flow Cytometry Standardized for Predicting Transplant Rejection

Understanding the immunological phenotype of transplant recipients on standard immunosuppression, immune-cell therapies and new drug treatments is essential for improving transplantation outcome. More...
12 Jun 2019
Image: The PLATELIA ASPERGILLUS Ag Test (Photo courtesy of Bio-Rad Laboratories).

Invasive Pulmonary Aspergillosis Diagnosed by Molecular Test

Invasive aspergillosis (IA) is a common opportunistic fungal infection, mainly affecting patients with severe and prolonged neutropenia. Early diagnosis of invasive pulmonary aspergillosis (IPA) is notoriously difficult, but crucial for prompt treatment initiation required to improve patient outcome. More...
12 Jun 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.