Molecular Diagnostics
Lynch Syndrome Screening by IHC Leads to Mutation Studies
Lynch syndrome or hereditary nonpolyposis colorectal cancer is an autosomal dominant genetic condition that is associated with a high risk of colon cancer, as well as other cancers including endometrial cancer, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. More...24 Oct 2019
Serum Levels of Neurofilament Light Chain Distinguish FTLD
While searching for biomarkers to diagnose frontotemporal lobar degeneration (FTLD), researchers employed the ultrasensitive single molecule array (Simoa) DNA analysis technique to detect neurofilament light chain (NfL) in cerebrospinal fluid (CSF) and, less invasively, from blood samples. More...23 Oct 2019
Immune Processes Linked to Multiple Sclerosis Genetics
Multiple sclerosis (MS) is an autoimmune inflammatory degenerative disease of the central nervous system that often starts in young adulthood and affects 2.3 million individuals worldwide. While prior genetic studies have implicated the adaptive immune system in the disease, in particular T cells, much of the genetic architecture of MS has remained unknown. More...17 Oct 2019
Methylation Signature Identified for Brain Metastases of Lung Cancer
When lung cancer metastasizes to the brain, it means the primary lung cancer has created a secondary cancer in the brain. About 20% to 40% of adults with non-small cell lung cancer go on to develop brain metastases at some point during their illness. More...17 Oct 2019
PCR Kit Developed for Detection of Q-fever Pathogen
Coxiella burnetii is an obligate intracellular bacterium that causes Q fever in animals and humans. The infection results from inhalation of a spore-like small-cell variant, and from contact with the milk, urine, feces, vaginal mucus or semen of infected animals. More...17 Oct 2019
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In Other News
Triple-Negative Breast Cancer Classified from Whole-Genome Sequencing
Multigene Testing for Breast Cancer Patients Proves Cost-Effective
New Blood Test Capable of Detecting Multiple Cancer Types
Two Different Mutations Identified as Cause of AML
Breath Analysis May Replace Blood Sampling to Monitor Drug Usage
Stunted Microbiota and Opportunistic Pathogen Colonize C-Section Birth
Parkinson’s Gene Mutation Linked to Higher Risk of Leukemia
Genetic Links Uncovered Between Psychotic Experiences
Molecular Changes Associated with Treating Lymphatic Filariasis
Some High-Cholesterol Genes Differ Between Countries
Non‐Invasive Prenatal Diagnosis of Spinal Muscular Atrophy Validated
Mitochondrial Clearance Failure Provides Diagnostic Marker for Parkinson's Disease
RT-PCR Evaluated for Diagnosis of Imported Schistosomiasis
Breakthrough Kit May Enable Early Alzheimer's Diagnosis
Drug-Resistant Strains of Salmonella Causing Bloodstream Infections
Targeted RNA Sequencing Technology Diagnoses Breast Cancer
New Guidelines Designed to Help Diagnose Chronic Diarrhea
New Strain of Bacteria Causes Scarlet Fever
Next-Gen Sequencing Matches Blood Group Antigens for Transfusion
Breath Analysis Identifies Cancer Patients Likely to Benefit from Immunotherapy
Distinctive mRNA Signatures May Prove Diagnostic for Cancer-Related AIS
Multiplex Microsphere Immunoassay Identifies Three Flavivirus Infections
Pathogenic Germline Variants Found in Breast Cancer Patients
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
