Molecular Diagnostics
LAMP Assay Validated for Visceral Leishmaniasis
Visceral leishmaniasis (VL) is one of the most neglected infectious diseases with an annual incidence of 50,000 to 90,000 new cases worldwide. Cases of VL are characterized by irregular bouts of fever, weight loss, hepatosplenomegaly, hypergammaglobulinemia, pancytopenia and anaemia. More...03 Dec 2018
Highly Multiplexed Broad Pathogen Assay Detects Infectious Diseases
Identifying the causative agent in an acute febrile illness can be challenging diagnostically, especially when organisms in a particular region have overlapping clinical presentation or when that pathogen’s presence is unexpected. More...29 Nov 2018
Acute Myeloid Leukemia Regulatory Networks Identified
Adult acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes abnormal myeloblasts (a type of white blood cell), red blood cells, or platelets. AML is a heterogeneous disease caused by a variety of alterations in transcription factors, epigenetic regulators and signaling molecules. More...28 Nov 2018
Pregnancy-Related Immune Changes Revealed by Placenta Sequencing
A team of scientists has used single-cell RNA sequencing to map expression profiles in the placenta, focusing on the decidua tissue that forms from the lining of the uterus and placental trophoblast tissue from the fetus that interacts with maternal cells. More...28 Nov 2018
Sensitive Tumor Detection Uses Cell-Free DNA Methylomes
A combination of "liquid biopsy," epigenetic alterations and machine learning has been used to develop a blood test to detect and classify cancer at its earliest stages. The method holds promise of being able to find cancer earlier when it is more easily treated and long before symptoms ever appear. More...27 Nov 2018
Biomarker Found for Prostate Cancer Treatment Response
Prostate cancer is one of the most common cancers in males and has one of the highest five-year survival rate when diagnosed in the localized stage. When diagnosed in the advanced stage or when a localized tumor relapses after the initial local treatment, the usual procedure is to fight it using male hormone (androgen) deprivation therapy. More...27 Nov 2018
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In Other News
Recognized Cause of Pediatric Mitochondrial Disease Found
Ovarian Cancer Test Measures Biomarker Serum Levels
Childhood Epilepsy Diagnoses Shift with Genomic Reinterpretation
Cell-Free DNA Sequencing Test for Infectious Disease Analyzed
Genetic Basis of Childhood-Onset Cardiomyopathies Identified
Potential Brain Tumor Liquid Biopsies Developed
Microsatellite Instability Assay Validated for Cancer Studies
Genetic Test Helps Patients Avoid Unnecessary Thyroid Surgery
Herpes Simplex Virus Assay, Sample-to-Answer Instrument Get FDA Clearance
Breast Cancer Risk Variant Type Determines Tumor Aggressiveness
RNA Defects Linked to Multiple Myeloma Progression
Blood Compatibility Assay Approved by FDA
Blood Test Identifies Heart Failure with Preserved Ejection Fraction
Spinal Fluid Fingerprint Distinguishes Brain Infections from Diseases
Combined DNA Technologies Analyzed for Malaria Diagnosis
Warfarin Bleeding Risk SNPs Identified in African Americans
HPV DNA Test Monitors Remission in Oral Cancer
Ultrasensitive Screening Platform Detects Pathogenic Bacteria
Functional Genomic Landscape of AML Analyzed
Myeloproliferative Neoplasms Fall into Genetic Subgroups
Multidrug-Resistant TB Outbreak Undetected by Standard Tests
Chronic Inflammation Linked to Risk for Alzheimer's Disease
Fatal Prostate Cancer Differentiated from Manageable Cancer
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.