Molecular Diagnostics
Prognostic Signature Described in HPV-Positive Cell Carcinomas
Human papilloma virus (HPV) is an etiological agent of oropharyngeal squamous cell carcinoma (OPSCC). Patients with HPV+ OPSCC have high long-term survival rates: however, current radiation protocols are aggressive and can result in life-long morbidities, including difficulty swallowing, chronic dry-mouth, and altered speech. More...23 Jan 2019
Genetic Methods Rapidly Diagnoses Huntington's Disease
People with Huntington's disease suffer from jerky body movements and decreasing mental abilities. The condition usually leads to death 15 to 20 years after diagnosis. The cause of the disease is a region in the Huntingtin gene (HTT) that is absent in healthy people. More...23 Jan 2019
Urinary Detection Method Developed for Prostate Cancer
Prostate cancer (PCa) is one of the most common types of malignancy worldwide and is the second leading cause of cancer death among men. This cancer tends to be asymptomatic and slow growing, often with onset in young men, but usually not detected until the age of 40 to 50 years. More...22 Jan 2019
Latinos and Hispanics Prone to Kidney Disease Gene Variant
Risk variants in the apolipoprotein A-I (APOL1) gene on chromosome 22, which were first discovered in African Americans, confer a substantially increased risk of kidney disease, early-onset hypertension, and cardiovascular disease, although disease risk is modified by other genetic factors and by environmental factors. More...21 Jan 2019
Tumor Sequencing Finds Mutations Caused by Blood Disorder
Clinical sequencing assays aim to identify somatic mutations in cancer cells for accurate diagnosis and treatment. However, most clinical-grade implementations lack patient-matched germline DNA, and supplemental analyses are needed to infer the mutational status of variants. More...15 Jan 2019
Newborn Genomic Sequencing Detects Disease Risk Factors
Genomic sequencing provides many opportunities in newborn clinical care, but the challenges of interpreting and reporting newborn genomic sequencing (nGS) results need to be addressed for its broader and effective application. More...15 Jan 2019
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In Other News
Tools for Meningitis Diagnostics Implemented in Resource-Limited Settings
LAMP Test Rapidly Detects Sexually Transmitted Chlamydia
New Risk Loci Identified for Polycystic Ovary Syndrome
Diverse Chronic Kidney Diseases Diagnosed with Exome Sequencing
Rapid Next-Gen Sequencing Method Predicts Prostate Cancer Risks
Metastatic Colorectal Cancer Linked to Transcription Factors
Epigenetic Cervical Cancer Test Has Perfect Detection Rate
Molecular Cause Found for Rare Autoimmune Disorders
Gut Microbes Differ Between Two Common Conditions
Sequencing Assay Adopted for Advanced Lung Cancer Reflex Testing
Neuroblastoma Molecular Analysis Leads to Prognostic Markers
Genetic and Epigenetic Features Found in Glioma Tumors
Tick-Borne Diseases Diagnosed with Multiplex Molecular Panel
HCV-RNA Present in Body Fluids in High Viral Load Patients
Banna Virus Detected by Reverse Transcription-Loop-Mediated Isothermal Amplification
Alzheimer's Disease Risk Alleles Profiled in Latino Populations
Genetic Marker Predicts Early Relapse in Pediatric ALL
Colorectal Cancer Risk Linked to Common and Rare Variants
Newborn Cytomegalovirus Test Cleared for Marketing
Unique Genetic Makeup of Myeloma Tumor Cells Profiled
Liquid Biopsy Identifies Advanced Lung Cancer Drivers
Metagenomic Sequencing Proposed for Respiratory Tract Infection Detection
Plasmodium vivax Isolated in Duffy Negative Individuals
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.