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Molecular Diagnostics

Image: The COBAS TaqMan HBV test (Photo courtesy of Roche Diagnostics).

Assay Detects Hepatitis B in Multiple Specimens

Hepatitis B virus (HBV) infection has led to more than 686,000 deaths worldwide per year. Approximately two billion individuals worldwide are infected with HBV and are at risk of developing cirrhosis and hepatocellular carcinoma, which ranks fifth in terms of malignant cancer mortality. More...
25 Apr 2018
Image: A diagram of a normal heart compared to hypertrophic cardiomyopathy (Photo courtesy of the Mayo Clinic).

Genetic Variant Identified As Better Marker for CV Disease

A newly identified subset of a known genetic variant found primarily in individuals of South Asian descent may be a better marker for carriers of heart dysfunction in this population and that individuals with this genetic variant are more likely to develop early signs of hypertrophic cardiomyopathy. More...
24 Apr 2018
Image: The ABI 7500 Real Time PCR System is a fully integrated system for real-time detection of PCR (Photo courtesy of Applied BioSystems).

CSF Examined for Enteroviral Nervous System Infection

Infections caused by enteroviruses are among the most common infectious diseases of the central nervous system (CNS). Enterovirus infections account for 40-77% of all viral meningitis cases in adults. An infection of the meninges results in an uncharacteristic headache usually accompanied by fever and neck stiffness. More...
19 Apr 2018
Image: Computer-generated illustration of Mycobacterium tuberculosis bacteria, Ziehl-Neelsen stain. Acid-fast bacilli stain red and the background is blue (Photo courtesy of Microbiology Pictures).

Blood Test Predicts Onset of TB in Advance

Tuberculosis, caused by infection with Mycobacterium tuberculosis (TB), is the world's leading cause of death brought on by a single pathogen. More than 10 million new cases of TB are diagnosed each year, and almost two million people die from the disease. More...
18 Apr 2018
Image: A diagram comparing normal and diseased in irritable bowel syndrome (Photo courtesy of HealthNormal).

Genetic Link to IBS Identified in Women

Irritable bowel syndrome is the most common gastrointestinal disorder. More than 10% of the population suffers from recurrent symptoms including abdominal pain, gas, diarrhea and constipation and it is more common in women than men. More...
18 Apr 2018
Image: A diagram of various stents used in angioplasty (Photo courtesy of Open Biomedical Initiative).

Genetic Test May Improve Post-Stent Treatment Outcome

A test for specific genetic mutations successfully informed blood-thinner treatment selection following stent placement to open clogged blood vessels, leading to significantly fewer complications. More...
17 Apr 2018

Amino Acids Can Predict CV Disease Risk in Women

Results of a recent study supported the hypothesis that plasma BCAAs (branched-chain amino acids) were positively associated with cardiovascular disease (CVD) risk and were linked to an intermediate diagnosis of type II diabetes (T2D). More...
16 Apr 2018
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