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Molecular Diagnostics

Image: Immunostaining of breast cancer; distribution pattern of the Ki67 labeling index in breast cancer values (Photo courtesy of University of Szeged).

Breast Cancer Risk Variant Type Determines Tumor Aggressiveness

Interval breast cancer is a term for tumors detected within a year after a mammographic screening that was determined to be normal and is among the measures used to gauge the efficacy of breast screening programs. More...
14 Nov 2018
Image: Bone marrow aspirate from a patient with multiple myeloma showing plasmacytosis (Photo courtesy of Feinberg School of Medicine).

RNA Defects Linked to Multiple Myeloma Progression

Multiple myeloma (MM) is the second most common type of blood cancer where cancer cells accumulate in the bone marrow, crowding out healthy blood cells. Studies on MM development have traditionally focused mostly on DNA abnormalities. More...
14 Nov 2018
Image: The ID Core XT blood group genotyping kit (Photo courtesy of Progenika Biopharma).

Blood Compatibility Assay Approved by FDA

Blood can be grouped based on the antigens on the surfaces of red blood cells, and the presence or absence of blood group antigens other than the ABO blood group antigens can be important in matching blood for transfusions. More...
12 Nov 2018
Image: A photomicrograph of heart cells (Photo courtesy of Cedars-Sinai Medical Center).

Blood Test Identifies Heart Failure with Preserved Ejection Fraction

A test based on a protein biomarker found in the blood is the basis of a scoring system that distinguishes patients with clinical heart failure with preserved ejection fraction (HFpEF) from healthy individuals and patients with risk factors but no heart failure. More...
12 Nov 2018
Image: Four vials of human cerebral spinal fluid of normal appearance, collected via lumbar puncture (Photo courtesy of Wikimedia Commons).

Spinal Fluid Fingerprint Distinguishes Brain Infections from Diseases

Cytokine profiling has been shown to distinguish patients with infections of the brain from other diseases and may become a valuable diagnostic tool, particularly in infants and young children. More...
12 Nov 2018
Image: The Loopamp Malaria Pan Detection Kit is a qualitative test for detection of Malaria Pan species (Plasmodium ovale, P. vivax, P. malariae and P. falciparum) in human blood samples (Photo courtesy of Human Diagnostics Worldwide).

Combined DNA Technologies Analyzed for Malaria Diagnosis

Malaria is one of the most important parasitic infectious diseases for which almost half of the world’s population is at risk. Although several diagnostic methods are now available to detect the infection, more sensitive and applicable tests are still required in the field. More...
08 Nov 2018
Image: The Human610-Quad BeadChip Kit uses the Infinium HD Super Assay and is compatible with the iScan, HiScan, and Bead Array Reader systems (Photo courtesy of Illumina).

Warfarin Bleeding Risk SNPs Identified in African Americans

Major Warfarin-related bleeding occurs more frequently in African Americans than in other populations. Identification of potential genetic factors related to this adverse event may help identify at-risk patients. More...
08 Nov 2018
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