Molecular Diagnostics
Sequencing Assay Adopted for Advanced Lung Cancer Reflex Testing
Guidelines are rapidly moving toward upfront profiling with next-generation sequencing (NGS) of all advanced lung cancers, but there are still practical issues with this testing method that can limit clinical testing and prevent or delay patients being started on targeted therapies. More...31 Dec 2018
Neuroblastoma Molecular Analysis Leads to Prognostic Markers
Neuroblastoma is a pediatric tumor of the sympathetic nervous system. Its clinical course ranges from spontaneous tumor regression to fatal progression. It most frequently starts from one of the adrenal glands, but can also develop in the neck, chest, abdomen, or spine. More...27 Dec 2018
Genetic and Epigenetic Features Found in Glioma Tumors
Neurofibromatosis type 1 (NF1) is a multisystem genetic disorder that is characterized by cutaneous findings, most notably café-au-lait spots and axillary freckling, by skeletal dysplasias, and by the growth of both benign and malignant nervous system tumors, most notably benign neurofibromas. More...27 Dec 2018
Tick-Borne Diseases Diagnosed with Multiplex Molecular Panel
Tick-borne diseases, which afflict humans and other animals, are caused by infectious agents transmitted by tick bites. Tick-borne illnesses are caused by infection with a variety of pathogens, including rickettsia and other types of bacteria, viruses, and protozoa. More...26 Dec 2018
HCV-RNA Present in Body Fluids in High Viral Load Patients
Hepatitis C virus (HCV) causes both acute and chronic infection. Acute HCV infection is usually asymptomatic, and is only very rarely (if ever) associated with life-threatening disease. About 15%–45% of infected persons spontaneously clear the virus within six months of infection without any treatment. More...26 Dec 2018
Banna Virus Detected by Reverse Transcription-Loop-Mediated Isothermal Amplification
Banna virus (BAV) has been isolated from a diverse group of vertebrates and invertebrates, including mosquitos, ticks, midges, cattle, and pigs from different regions in China, Vietnam, and Indonesia. BAV is considered to be an emerging pathogen that can result in human infections with possible manifestation of fever and viral encephalitis. More...25 Dec 2018
Alzheimer's Disease Risk Alleles Profiled in Latino Populations
The apolipoprotein E (APOE) gene encodes three common isoforms known as ε2, ε3, and ε4. These are determined by two single nucleotide polymorphisms (SNPs) that result in amino acid substitutions and associated functional changes in the protein. More...24 Dec 2018
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In Other News
Genetic Marker Predicts Early Relapse in Pediatric ALL
Colorectal Cancer Risk Linked to Common and Rare Variants
Newborn Cytomegalovirus Test Cleared for Marketing
Unique Genetic Makeup of Myeloma Tumor Cells Profiled
Liquid Biopsy Identifies Advanced Lung Cancer Drivers
Metagenomic Sequencing Proposed for Respiratory Tract Infection Detection
Plasmodium vivax Isolated in Duffy Negative Individuals
MALDI-TOF MS Identifies Oomycete Causing Pythiosis
Circulating Tumor DNA Detects Early Melanoma Growth
Methylation-Based Liquid Biopsy Test Detects Liver Cancer
Liquid Biopsy Detects Cancer across Multiple Biomarkers
DNA Recombination in Brain Linked to Alzheimer's Disease
Genes Identified That Predispose People to Chronic Kidney Disease
LAMP Assay Validated for Visceral Leishmaniasis
Nanopore Method Detects Single Influenza Virus at Single Particle Level
Highly Multiplexed Broad Pathogen Assay Detects Infectious Diseases
Acute Myeloid Leukemia Regulatory Networks Identified
Pregnancy-Related Immune Changes Revealed by Placenta Sequencing
Sensitive Tumor Detection Uses Cell-Free DNA Methylomes
Biomarker Found for Prostate Cancer Treatment Response
Recognized Cause of Pediatric Mitochondrial Disease Found
Ovarian Cancer Test Measures Biomarker Serum Levels
Childhood Epilepsy Diagnoses Shift with Genomic Reinterpretation
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.