Molecular Diagnostics

Plasma or Urine Liquid Biopsy Tests May Guide Colorectal Cancer Treatment
A recent paper suggested that liquid biopsy examination of blood or urine could aid in evaluating the effectiveness of therapy for colorectal cancers that had begun to metastasize beyond the site of the original tumor. More...23 Feb 2021

Proteogenomic and Metabolomic Studies Characterize Human Glioblastoma
Glioblastoma (GBM) is an aggressive type of cancer that can occur in the brain or spinal cord. Glioblastoma forms from cells called astrocytes that support nerve cells. Glioblastoma can occur at any age, but tends to occur more often in older adults. It can cause worsening headaches, nausea, vomiting and seizures. More...23 Feb 2021

Study Confirms Value of the MyProstateScore Urine Test for Prostate Cancer Screening
A recent paper confirmed that the MyProstateScore test could be used with confidence to detect clinically significant (grade group higher than 2) prostate cancers when compared to commonly used prostate specific antigen-based diagnostic screening. More...22 Feb 2021

Next Generation Sequencing Finds More Gene Mutations for Leukemia
Myeloid malignancies are characterized by uncontrolled proliferation and/or defects in differentiation of abnormal myeloid progenitor cells. Myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPNs) are often thought to be precursors to a higher grade myeloid malignancies, namely acute myeloid leukemia (AML). More...18 Feb 2021

Exome Sequencing Identified Pathogenic Variants in Cerebral Palsy Patients
Cerebral palsy (CP) is a group of permanent movement disorders that appear in early childhood. Signs and symptoms vary among people and over time. Often, symptoms include poor coordination, stiff muscles, weak muscles, and tremors. More...18 Feb 2021


In Other News
TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
Prolonged Maternal Zika Viremia Evaluated for Adverse Perinatal Outcomes
Early Plasma Biomarkers Discovered for Alzheimer's Disease
TAP1 Gene Polymorphisms Associated with Recurrent Respiratory Papillomatosis
Liquid Biopsy Allows Monitoring of COVID-19 Damage to Cells, Tissues, and Organs
Blood Test Detects Early Colorectal Adenomas
Precise Measurement of DNA Length Polymorphisms Used to Diagnose Acute Myeloid Leukemia
Liquid Biopsy Predicts Colon Cancer Relapse Months Earlier
Cell-Free DNA Detects Heart Allograft Acute Rejection
AI-guided Immunoassay Measures Maternal Autoantibodies to Predict Likelihood of Autism Spectrum Disorder
A Rapid AI-based Screening Test for Prostate Cancer Biomarkers in Urine
ABO Histo-Blood Groups Influence Makeup of Gut Microbiome
Specific RUNX1 Mutations Cause Different Disease Types
Study Confirms Performance of Rapid Stool Test for Detection of Colorectal Cancer
Monitoring of Urinary Eicosanoids Distinguishes Mild and Severe Asthma
Mismatch Repair/Microsatellite Instability Evaluated Using Cytology Effusion Specimens
Panel of MicroRNAs Differentiates Uncomplicated and Severe Malaria in Children
Metastatic Gastric Cancer Outcomes Informed by Single-Cell Transcriptome Profiles
Alzheimer's Disease Subtypes Proposed from Brain Gene Expression Profiles
Common Brain Malformation Traced to Its Genetic Roots
Predicting Thrombosis Risk in SLE Patients by Monitoring Blood Levels of Hydroxychloroquine
Elevated Galectin-1 Levels in Sepsis Reflect Danger of Cytokine Storm Development
Next Generation Sequencing Developed for Monitoring of Mixed Chimerism
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.