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Molecular Diagnostics

Image: A premature baby being monitored in a neonatal intensive care ward (Photo courtesy of 123rf.com)

Epigenetic Biomarker Signature Predicts the Likelihood of Premature Birth

Researchers have identified an epigenetic biomarker signature for preterm birth that can be used in a clinical setting to predict the likelihood that a pregnant woman might deliver prematurely. More...
07 Mar 2022
Image: Semiconductor sensor detects antigen molecules (Photo courtesy of Toyohashi University of Technology)

Semiconductor Microchip Detects Prostate Cancer Markers With Ultra-High Sensitivity

Researchers have developed a semiconductor sensor capable of detecting ultra-low concentrations of tumor markers, on chips made using semiconductor micromachine technology. More...
07 Mar 2022
Image: MYACUTECASE (Photo courtesy of bioMérieux)

Biomérieux Launches Free Mobile App to Aid Clinicians in Emergency and Critical Care Diagnostics

A free mobile application aims to support clinicians in decision-making and monitoring of patients using emergency and critical care diagnostics. In hospitals, particularly for emergency cases, diagnostic options can be limited for patients with acute and complex pathologies. More...
04 Mar 2022
Image: Monitoring blood pressure (Photo courtesy of 123rf.com)

Mitochondrial Damage May Explain the Increased Incidence of Hypertension in Black Adults

Increased plasma concentration of the enzyme xanthine oxidase (XO) and the resulting mitochondrial DNA damage that it can cause may explain why Blacks have a significantly higher incidence of hypertension than their White counterparts. More...
03 Mar 2022
Image: Strong nuclear and cytoplasmic p16 staining of a section from an HPV+ oropharynx tumor. Lymphocytes (blue arrow) and endothelial cells (black arrow) are unstained (Photo courtesy of Jonathon McHugh, MD)

TTMV-HPV DNA Biomarker Predicts Recurrence of Oropharynx Cancer

A large, multi-institutional study demonstrates that a blood test to detect circulating tumor DNA can accurately predict recurrence of HPV-driven oropharyngeal cancer following treatment. Results also indicate that the biomarker test may detect recurrent disease earlier than imaging or other standard methods of post-treatment surveillance, allowing physicians to personalize treatment more quickly for patients whose cancer returns. More...
03 Mar 2022
Image: Lipoprotein(a), or Lp(a), is a distinctive particle with two components: a lipoprotein core that resembles LDL, along with a shell that contains apolipoprotein(a), or apo(a).

Two Important Cardiovascular Disease Risk Factors Operate Independently

Determination of blood levels of the cholesterol-rich biomarker lipoprotein(a) [Lp(a)] and the coronary artery calcium (CAC) score are independently associated with risk of developing coronary artery disease and may be useful concurrently for guiding therapy approaches to prevent its occurrence . More...
02 Mar 2022
Image: Dr. Randall J. Bateman inspects a mass spectrometry instrument like that used to develop a blood test that is up to 93% accurate at identifying people at risk of Alzheimer`s disease (Photo courtesy of Matt Miller)

Sensitive Diagnostic Test for Alzheimer’s Disease Demonstrates Accuracy Over Multiple Laboratories and Protocols

The diagnostic accuracy of a blood test that assesses whether amyloid plaques have begun accumulating in the brain based on the ratio of the levels of the amyloid beta proteins ABeta42 and ABeta40 was confirmed in a recent study. More...
01 Mar 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.