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Molecular Diagnostics

Image: Schematic diagram of image-enabled cell sorting, developed at BD Biosciences and tested by European Molecular Biology Laboratory (Photo courtesy of BD Bioscience)

High-Speed Fluorescence Image-Enabled Cell Sorting Tested

Cell sorting through flow cytometry is a technique that enables scientists to identify and sort individual cells based on specific characteristics of each cell in order to study them in more detail, evaluate how each cell may react to a new drug or perform other single cell studies. More...
03 Feb 2022
Image: SNRPN (Small nuclear ribonucleoprotein-associated protein N). SNRPN-methylation is used to detect imprinting errors on chromosome 15 (Photo courtesy of Wikimedia Commons)

Novel Blood Test Diagnoses Newborns with Rare Genetic Disorders

A team of Australian researchers has developed a test to screen newborns for three rare genetic disorders simultaneously. More...
01 Feb 2022
Image: The NovaSeq 6000 Sequencing system (Photo courtesy of Illumina)

Transcriptomic Analysis Reveals Proinflammatory Signatures Associated with AML Progression

Acute myeloid leukemia (AML) is believed to arise through a combination of genetic alterations and aberrant gene expression patterns caused by genetic and epigenetic changes, which in their composition also determine AML progression and therapy resistance. More...
01 Feb 2022
Illustration

Meridian Bioscience Launches Two New Master Mixes That Detect DNA and RNA in Crude Saliva Samples

Meridian Bioscience, Inc. (Cincinnati, OH, USA) has launched two new master mixes that detect DNA and RNA in crude saliva samples. More...
01 Feb 2022
Image: Micrograph of prostate adenocarcinoma, acinar type, the most common type of prostate cancer (Photo courtesy of Wikimedia Commons)

Epigenetic Biomarkers Increase Sensitivity of Prostate Cancer Liquid Biopsy Diagnostic Tests

A team of Austrian researchers identified additional epigenetic biomarkers that will upgrade the diagnosis of advanced prostate cancer by increasing the sensitivity of liquid biopsy analysis of circulating tumor DNA. More...
31 Jan 2022
Image: The ultrarapid genome sequencing pipeline, indicating all processes from sample collection to a diagnosis. Vertically stacked processes are run in parallel (Photo courtesy of Stanford University)

Ultrarapid Nanopore Genome Sequencing in a Critical Care Setting

A genetic diagnosis can guide clinical management and improve prognosis in critically ill patients, and much effort has gone into developing methods that result in rapid, reliable results. More...
27 Jan 2022
Image: BreathBiopsy Collection Station (Photo courtesy of Owlstone Medical)

Novel Breath-Based Diagnostics Could Indicate Early Rejection of Organs in Lung Transplant Patients

SQI Diagnostics Inc. (Ontario, Canada) and Owlstone Medical (Cambridge, UK) have signed a Memorandum of Understanding (MOU) to work together on the discovery, development and commercialization of breath-based biomarkers relating to invasive aspergillus lung infection and lung transplant rejection. More...
26 Jan 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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