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Molecular Diagnostics

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New CRISPR-Based Assay Detects Biomarker of Kidney Transplant Rejection in Urine

Researchers have developed a CRISPR-based assay that can sensitively and non-invasively detect a biomarker of acute kidney rejection in urine. More...
19 Jan 2022
Image: Fastest DNA sequencing technique diagnoses rare genetic diseases in mere hours  (Photo courtesy of Stanford Medicine)

Fastest DNA Sequencing Technique Diagnoses Rare Genetic Diseases in Mere Hours

A research effort has set the first Guinness World Record for the fastest DNA sequencing technique, which was used to sequence a human genome in just five hours and two minutes. More...
19 Jan 2022
Image: The SMARTer Stranded Total RNA-Seq Kit v2 - Pico Input Mammalian is used to generate strand-specific RNA-seq libraries (Photo courtesy of Takara Bio)

Cell-free RNA Profiles Gauge Preeclampsia Risk Months Before Symptoms

The period from conception to delivery represents the most rapid growth and development in an individual’s life. The ability to support this development requires dramatic and inadequately understood alterations in maternal physiology. More...
18 Jan 2022
Image: Optimized reaction time for Multiple Cross Displacement Amplification (MCDA-LFB) assay to detect Legionella pneumophila. The best sensitivity was seen when the amplification lasted for 35 minutes (Photo courtesy of Zhejiang Provincial People’s Hospital)

MCDA-LFB Assay Developed for Rapid Detection of Legionnaires’ Disease

Legionella pneumophila is an opportunistic waterborne pathogen of significant public health problems, which can cause serious human respiratory diseases (Legionnaires’ disease). Legionnaires’ disease is characterized by severe lung infection symptoms, including severe pneumonia with a high fatality rate. More...
18 Jan 2022
Image: A chest X-ray showing a tumor in the lung (marked by arrow) (Photo courtesy of Wikimedia Commons)

Tumor Biomarker Panel Improves Identification of Candidates for Lung Cancer Screening

Use of a blood-based tumor biomarker panel in combination with modeling according to results of PLCOm2012 (Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial) significantly improved risk assessment for lung cancer screening. More...
17 Jan 2022
Image: Curian immunofluorescent testing platform (Photo courtesy of Meridian Bioscience, Inc.)

Meridian Receives FDA Clearance for Rapid Fluorescent Immunoassay for Detection of Campylobacter Infection

Meridian Bioscience, Inc. (Cincinnati, OH, USA) has received U.S. Food and Drug Administration (FDA) clearance for its Curian Campy assay developed to be utilized on the Curian immunofluorescent testing platform. More...
14 Jan 2022
Image: QX200 AutoDG ddPCR System and QXDx BCR-ABL %IS Kit (Photo courtesy of Bio-Rad)

ddPCR Developed for BCR-ABL1 Fusion Transcript in B-Lymphoblastic Leukemia

Droplet digital polymerase chain reaction (ddPCR) is a novel polymerase chain reaction (PCR) technique reliant on massive sample partitioning to generate individual reaction chambers (droplets) in which individual amplification targets are detected. More...
12 Jan 2022
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