Molecular Diagnostics
Leptomeningeal Disease Diagnosed Using CSF Cell-Free DNA
Leptomeningeal disease (LMD) is a devastating complication of solid and liquid systemic and central nervous system malignant neoplasms. LMD, in which cancer metastasizes to the cerebrospinal fluid, occurs in 4% to 15% of cancer patients and is associated with poor survival, with untreated patients dying within four to six weeks. More...26 Aug 2021
Various Serum Vitamin D Biomarkers Compared for Sarcopenia
Sarcopenia is an age-related clinical condition characterized by a gradual and generalized loss of skeletal muscle mass with a decrease in strength and physical capacity. It is considered to be one of the risk factors for adverse events in older people, including delirium, disability, institutionalization, and even death. More...25 Aug 2021
![Image: Two-dimensional structure of lactosylceramide (Lac-Cer). Lac-Cer levels in the circulation could have prognostic value for SLE patients with CVD (Photo courtesy of [U.S] National Library of Medicine)](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2021-08-23/GMS-067B.jpg "Image: Two-dimensional structure of lactosylceramide (Lac-Cer). Lac-Cer levels in the circulation could have prognostic value for SLE patients with CVD (Photo courtesy of [U.S] National Library of Medicine)")
Sphingolipids Are Prognostic Biomarkers for African American SLE Patients with Cardiovascular Disease
A recent study found that lactosylceramide levels may have a “predictive” value and sphingolipidomics have an added benefit to currently available tools for the early diagnosis and prognosis of African American systemic lupus erythematosus (SLE) patients with cardiovascular disease (CVD). More...23 Aug 2021
CSF biomarkers Compared for Down Syndrome and Inherited Alzheimer’s
Although most people with Down’s syndrome will experience brain changes as they age, not everyone will develop Alzheimer’s disease or another type of dementia. Whilst having Down’s syndrome does put a person at increased risk, estimated at 1 in 3 people in their 50s, and closer to 2 in 3 aged over 60, it is not inevitable for all. More...19 Aug 2021
![Image: Gross pathology of idiopathic cardiomyopathy. Opened left ventricle of heart shows a thickened, dilated left ventricle with subendocardial fibrosis manifested as increased whiteness of endocardium (Photo courtesy of [U.S.] Centers for Disease Control and Prevention)](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2021-08-17/GMS065.jpg "Image: Gross pathology of idiopathic cardiomyopathy. Opened left ventricle of heart shows a thickened, dilated left ventricle with subendocardial fibrosis manifested as increased whiteness of endocardium (Photo courtesy of [U.S.] Centers for Disease Control and Prevention)")
A Circulating Adipokine Is a Possible Biomarker for Severity of Systemic Sclerosis-Associated Interstitial Lung Disease
A circulating adipokine (a cytokine chemical messenger produced by adipose tissue) has been identified as a possible biomarker associated with the severity of systemic sclerosis-associated interstitial lung disease. More...15 Aug 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.