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Molecular Diagnostics

Image: The limulus amebocyte lysate (LAL) assay measures endotoxin activity (Photo courtesy of HyCult Biotechnology)

Endotoxemia Genetic Profile Reveals an Association with Thromboembolism and Stroke

Microorganisms are part of the human body, and bacteria or their components often end up in the circulation. One such bacterial component is lipopolysaccharide (LPS), which is a toxin. High concentrations of LPS in the blood cause sepsis. Low LPS levels, known as endotoxemia, cause low-grade inflammation. More...
09 Nov 2021
Image: Crystal structure of interleukin-6 (IL-6) (Photo courtesy of Wikimedia Commons)

Inflammatory Cytokine Levels Predict Patient Outcomes After Traumatic Injury

Measurement of the inflammatory cytokines interleukin-6 (IL-6) and interleukin-8 (IL-8) can be used to predict patient outcomes after traumatic injury. More...
09 Nov 2021
Image: Immunohistochemical analysis using a labeled antibody for TPD52 recognition (Photo courtesy of GeneTex)

New Biomarker Improves Definition of Medulloblastoma Risk

An immunohistochemistry marker has been identified as being able to improve risk stratification of medulloblastoma, the most common form of pediatric brain tumor, using a technique that is within the capabilities of most clinical laboratories. More...
08 Nov 2021
Image: STARlet-AIOS (Photo courtesy of Seegene, Inc.)

Seegene Launches STARlet-AIOS All-in-One System that Fulfills Critical Need for Fully Automated, High-Throughput Real-Time PCR Testing

Seegene, Inc. (Seoul, Korea) has launched its fully automated STARlet-AIOS: All-in-One System (AIOS) that addresses the needs of small, mid-sized, and large hospitals and COVID-19 laboratories. More...
03 Nov 2021
Image: Estimated cost-effectiveness of genetic testing in siblings of newborns with cancer susceptibility gene variants (Photo courtesy of Lockton, Inc)

Sibling Cascade Testing More Cost Effective in Pediatric Cancer

Newborn population-based genetic screening may reduce pediatric cancer deaths and could be cost-effective. Testing siblings of newborns with variants (i.e., cascade testing) could further improve population health. More...
02 Nov 2021
Image: Example of gene duplication that has created a copy number variation. The chromosome now has two copies of this section of DNA, rather than one (Photo courtesy of Wikimedia Commons)

A Liquid Biopsy Approach for Predicting Likely Relapse Following Treatment of Medulloblastoma in Children

A liquid biopsy technique that determines the level of cell-free DNA in cerebrospinal fluid (CSF) can be used to detect measurable residual disease (MRD) in children being treated for the malignant brain tumor medulloblastoma. More...
02 Nov 2021
Image: The Envisia Genomic Classifier Improves Idiopathic Pulmonary Fibrosis Diagnosis (Photo courtesy of Clinical Lab Products)

Gene Expression Test Improves Idiopathic Pulmonary Fibrosis Diagnosis

Idiopathic pulmonary fibrosis (IPF) is a serious chronic disease that affects the tissue surrounding the air sacs, or alveoli, in the lungs. This condition occurs when that lung tissue becomes thick and stiff for undetermined reasons. More...
01 Nov 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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