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BioResearch

Image: T-cells interacting with the transparent gel (Photo courtesy of Hawley Pruitt, Johns Hopkins University).

Hydrogel Cultivation Generates Large Populations of Activated T-Cells

A novel hydrogel-based culture system was used to generate activated immune T-cells that were shown to be able to block growth of melanoma tumors in a mouse model. More...
30 Apr 2019
Image: A histopathological image of multiple myeloma from a bone marrow aspirate (Photo courtesy of Wikimedia Commons).

Gene Translocation Marker Linked to Drug Resistance and Poor Prognosis

Cancer researchers have identified a genetic marker linked to the likelihood of a bad prognosis for some patients suffering from multiple myeloma. More...
29 Apr 2019
Image: The use of WES on adults with liver disease of unknown cause illustrates the potential clinical value of genome rounds in the individual assessment and medical care of patients (Photo courtesy of the Yale School of Medicine / Journal of Hepatology).

Unexplained Liver Disease Diagnosed by Whole-Exome Sequencing

A recent paper promoted the use of whole-exome sequencing (WES) to detect and diagnose cases of unexplained liver disease. More...
29 Apr 2019
Image: T. fusca, a source of Cas3 nuclease (Photo courtesy of Microbe Wiki).

Version of CRISPR/Cas3 More Impactful Gene-Editing Tool

A less precise but more impactful version of the CRISPR/Cas9 gene-editing tool was described in a recent paper. More...
23 Apr 2019
Image: A catalog of deletions (4,489) observed in brain samples derived from both healthy subjects and subjects with psychiatric disorders. The burden of deletions accumulates in various brain regions during aging. Many deletions play a major role in classical mitochondrial disorders, and deletion burden is viewed as an indicator of long lasting mitochondrial oxidative stress. Each colored ribbon is composed of individual lines showing the relative amount of deletions in brain samples in the catalog (Photo courtesy of the University of California, Irvine).

New Technique Detects Breaks in Mitochondrial DNA

The Splice-Break pipeline is a recently described technique that can detect and quantify mitochondrial DNA (mtDNA) deletions at a high level of resolution. More...
22 Apr 2019
Image: A color photograph of a kidney stone – eight millimeters in length (Photo courtesy of Wikimedia Commons).

Genome Study Identifies Kidney Disease Risk Factor Genes

A large genome-wide association study identified 14 variants, including nine new variants, at different genetic loci that were linked to the development of urolithiasis (kidney stone disease). More...
22 Apr 2019
Image: A diagram of the epidermal growth factor receptor (EGFR) (rainbow colored, N-terminus = blue, C-terminus = red) complexed its ligand epidermal growth factor (magenta) (Photo courtesy of Wikimedia Commons).

Targeting MicroRNA Blocks Drug Tolerance in Some Cancers

Cancer researchers have suggested that by exploiting the link between a specific microRNA and the tricarboxylic acid energy-producing cycle it may be possible to prevent or reverse the development of drug tolerance or resistance by non-small-cell lung carcinomas. More...
15 Apr 2019
New
Gold Member
Clinical Chemistry Assay
Sorbitol Dehydrogenase (SDH)
POC Helicobacter Pylori Test Kit
Hepy Urease Test
New
Electrolyte Analyzer
CBS-4000 (CBS-400)
New
Urine Analyzer
respons® UDS100


BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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