Acoustic Assay Launched to Increase Productivity of Protein Analyses

A new, six-plate cartridge format for Acoustic Assays was launched that will enable larger, cost efficient protein analysis studies.

BioScale, Inc., (Lexington, MA, USA) launched a new, six-plate cartridge format for its Acoustic Assays to enable larger protein analysis studies, with unprecedented cost efficiency. The product enhancement, for use on the Bioscale's proprietary ViBE instrumentation platform, will be introduced at the American Association of Pharmaceutical Scientists (AAPS) National Biotechnology Conference in San Diego (CA, USA) which will take place during November 2–6, 2014.

Christopher Silva, vice president, commercial operations at BioScale said, "Our ViBE platform, paired with our nonoptical Acoustic Assays, overcomes limitations of traditional methods like ELISA or Western blot by providing a simple, highly sensitive method of measuring specific proteins in a complex sample, with walk-away automation. This enables fast assay development—that takes days, rather than months." Mr. Silva added, "Now, our new six-plate format enables even larger studies—providing up to 576 data points in one cartridge—at a cost as low as only USD 2 per sample well. This will be particularly important for scientists needing to study cell signaling pathways and biomarkers […]."

BioScale's ViBE platform enables nonoptical, acoustic protein measurement utilizing BioScale's proprietary Acoustic Membrane MicroParticle (AMMP) Acoustic Membrane MicroParticle technology. The company's Acoustic Assays measure analyte concentration by determining changes in oscillation frequency caused by the binding of microparticles to the sensor surface. To date, the platform featured 1-, 2- and 3-plate cartridge formats allowing up to 288 samples per cartridge. Now, the six-plate format allows up to 576 individual data points in a single assay or the reuse of the cartridge for multiple assays for up to 576 measurements across 5 days.

The ViBE platform is a novel protein measurement technology enabling highly sensitive, automated Acoustic Immunoassays to accelerate drug discovery, development and production of biological and pharmaceutical products. The sensitivity, precision, and walk-away capabilities of our non-optical AMMP technology enables customers to achieve breakthrough advancements in protein research that were not previously attainable via traditional ELISA, Western blot and IHC methods, allowing ultra-sensitive detection of proteins in complex biological samples. The company's instrumentation platform is used by leading biopharmaceutical companies, academic institutions and government laboratories.

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