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Pathology

Certest Offers Real-Time PCR Assays for Fast Detection of MDR Bacterial Infections

CerTest Biotec (Zaragoza, Spain; www.certest.es) has joined the fight against multidrug resistant strains (MDR) bacterial infections by developing real-time PCR assays for the fast detection of genes or punctual mutations that confer resistance to antibiotics from both Gram-positive and Gram-negative pathogens. More...
23 Sep 2021
Image: The BD FACSLyric Flow Cytometry System (Photo courtesy of BD Diagnostics)

Encephalitis After Immunotherapy Detected Early by Blood Test

Immunotherapy is very effective for many cancers, but the treatment can also cause autoimmune side effects. Encephalitis is one of the most serious and difficult-to-diagnose side effects of immunotherapy. More...
16 Sep 2021
Image: The Invitrogen Qubit 4 Fluorometer is designed to accurately measure DNA, RNA, and protein quantity (Photo courtesy of Thermo Fisher Scientific)

Blood Testing Distinguishes Benign Tumors from Precancerous Condition

The leading cause of mortality for patients with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is the development of malignant peripheral nerve sheath tumor (MPNST), an aggressive soft tissue sarcoma. In the setting of NF1, this cancer type frequently arises from within its common and benign precursor, plexiform neurofibroma (PN). More...
15 Sep 2021
Image: The NanoQuant infinite M200 pro reader is an easy-to-use multimode plate reader family (Photo courtesy of Neotec Scientific Instrumentation)

CCN1 Analyzed as a Biomarker for Breast Cancer Detection

Breast cancer is the most frequent malignancy in women with 1.7 million new cases and over 500,000 deaths worldwide in 2016. Early detection of cancer is believed to be crucial in reducing cancer death. Despite recent progress in liquid biopsy technologies, early blood-based detection of breast cancer is still a challenge. More...
14 Sep 2021
Image: Schematic representation of cancer-related biomolecules such as cells, proteins, nucleic acids, miRNA and microvesicles circulating into the bloodstream, and collection of these biomarkers by liquid biopsy (Photo courtesy of University of Florence)

Liquid Biopsy Assay Evaluated for Early Detection of Gastric Cancer

Gastric cancer (GC) is the fourth most-commonly diagnosed cancer, and the third leading cause of cancer-associated mortality worldwide. Despite improvements in treatment modalities, the prognosis for advanced GC following curative resection remains poor. More...
08 Sep 2021
Image: The CellSearch Circulating Tumor Cell Kit is intended for the enumeration of circulating tumor cells of epithelial origin (CD45-, EpCAM+, and cytokeratins 8, 18+, and/or 19+ and PD-L1) in whole blood (Photo courtesy of CellSearch/Menarini Silicon Biosystems)

PD-L1 Expression in Circulating Tumor Cells Investigated for NSCLC

In non-small cell lung cancer (NSCLC), analysis of programmed cell death ligand 1 (PD-L1) expression in circulating tumor cells (CTCs) is a potential alternative to overcome the problems linked to the tumor biopsy spatiotemporal heterogeneity. However, the prognostic significance of PD-L1-positive [PD-L1(+)] CTCs remains controversial. More...
07 Sep 2021
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World's First AI-Powered Solution for Gastrointestinal Cancer Diagnostics to Help Pathologists Reduce Turnaround Time

The world's first Artificial Intelligence (AI)-powered solution for gastrointestinal (GI) cancer diagnostics is helping pathologists improve accuracy and efficiency of GI cancer diagnosis in routine practice. More...
05 Sep 2021
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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