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Pathology

Image: A histopathology of Hirschsprung’s disease, which is characterized by the absence of parasympathetic ganglion cells in both submucosal as well as myenteric plexuses in the distal gastrointestinal tract (Photo courtesy of Dr. Dharam Ramnani).

Suite of Risk Variants Revealed in Hirschsprung's Disease

Hirschsprung’s disease, or congenital aganglionosis, is a developmental disorder of the enteric nervous system and is the most common cause of intestinal obstruction in neonates and infants, often appearing in combination with other symptoms in a manner that may reflect specific syndromes. More...
23 Apr 2019
Image: A gram-negative stained culture of Fusobacterium nucleatum (Photo courtesy of J. Michael Miller, Ph.D., (D)ABMM).

CRC Gut Microbial Signatures Lead to Diagnostic Tests

Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine). A cancer is the abnormal growth of cells that have the ability to invade or spread to other parts of the body. More...
18 Apr 2019
Image: The Envisia Genomic Classifier Kit improves diagnosis for patients undergoing evaluation for interstitial lung diseases (ILDs), including idiopathic pulmonary fibrosis (IPF) (Photo courtesy of Veracyte).

Genomic Classifier Test for Lung Disease Validated

In the appropriate clinical setting, the diagnosis of idiopathic pulmonary fibrosis (IPF) requires a pattern of usual interstitial pneumonia to be present on high-resolution chest computerized tomography (HRCT) scan or surgical lung biopsy. More...
18 Apr 2019
Image: Droplet digital PCR measures tumor load by non-invasive means. The technique takes advantage of the cell-free DNA circulating in blood, which is found in higher concentration in cancer patients (Photo courtesy of Christof Winter, MD, PhD).

Liquid Biopsy Potential Tested with ddPCR Technology

Droplet digital polymerase chain reaction (ddPCR) technology has been used to investigate the benefits of tracking drug-resistance mutations in the circulating DNA (ctDNA) of patients with hormone receptor-positive (HR+) metastatic breast cancer. More...
10 Apr 2019
Image: A photomicrograph of a pleural fluid cytopathology specimen showing mesothelioma (Photo courtesy of Nephron).

Malignant Pleural Mesothelioma Personalized by ctDNA Profiling

Malignant pleural mesothelioma (MPM) is an aggressive tumor associated with exposure to asbestos and is rising in incidence worldwide. More...
09 Apr 2019
Image: The UltraClean PCR cleanup kit (Photo courtesy of MO BIO Laboratories).

Fecal Microbes Used to Diagnose Liver Cirrhosis

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic liver disease worldwide, and yet remains largely underdiagnosed even in individuals with advanced stage of the disease. More...
09 Apr 2019
Image: Human IL-6 Luminex Performance ELISA Assay (Photo courtesy of R&D Systems).

Haptoglobin Expression Linked to Newborn Outcomes

Proteomics has facilitated discovery of biomarkers to better understand the pathophysiology of early-onset neonatal sepsis with the goal of identifying as early as possible the newborns more likely to die or develop significant morbidity. More...
09 Apr 2019
New
Gold Member
ANA & ENA Screening Assays
ANA and ENA Assays
Antipsychotic TDM AssaysSaladax Antipsychotic Assays
New
Gold Member
Syphilis Screening Test
VDRL Antigen MR
New
Alpha-1-Antitrypsin ELISA
IDK alpha-1-Antitrypsin ELISA


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.