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Pathology

Image: The Quick-Ray Manual Tissue Microarrayer Set (Photo courtesy of Unitma).

Diagnostic Panel Analysis of Lung Cancer Compared

Lung cancer is the leading cause of cancer death. Non-small cell lung carcinomas are the most common type of lung cancers. They can further be divided into adenocarcinomas and squamous cell carcinomas. Accurately classifying these tumors is important to select the best treatment options for patients. More...
25 Sep 2019
Image: The Ventana Discovery ultra biomarker platform stainer (Photo courtesy of Roche Diagnostics).

Diagnostic Biomarker Expression Compared for Metastatic Tumors

Metastatic mucinous tumors pose a unique diagnostic challenge for the surgical pathologist as their morphologic and clinical characteristics are often nonspecific. The colorectum is the most common site of origin. More...
25 Sep 2019

Differences in Gut Bacteria May Predispose to Heart Attacks

Heart attacks can occur when a person has developed heart disease. A key feature of heart disease is the buildup of plaque in the arteries. Plaque is made up of fat, calcium, and other substances. More...
19 Sep 2019
Image: A melanoma on a patient\'s skin. Most melanomas are black or brown, but they may also be skin-colored, pink, red or purple. People with chronic lymphocytic leukemia are at a higher risk for melanomas (Photo courtesy of the National Cancer Institute).

Chronic Lymphocytic Leukemia Linked with Higher Melanoma Risk

Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. Chronic lymphocytic leukemia (CLL) is a type of cancer that starts from white blood cells (called lymphocytes) in the bone marrow. More...
19 Sep 2019
Image: The TripleTOF 6600 Quadrupole Time-Of-Flight (QTOF) mass analyzer (Photo courtesy of Sciex).

Protein Panel Developed for Early Detection of Lung Cancer

Lung cancer is the most common cause of cancer-related mortality worldwide, characterized by late clinical presentation as 49%–53% of patients are diagnosed at stage IV, and consequently have poor outcomes. More...
18 Sep 2019
Image: The multigene germline panel test prospectively searches for pathogenic or likely pathogenic variants in 30 genes (Photo courtesy of Color Genomics).

Pathogenic Germline Variants Found in Breast Cancer Patients

There is still considerable debate on the value of multigene panel testing for inherited cancer in patients with breast cancer, based on both the prevalence of pathogenic/likely pathogenic (P/LP) variants and any therapeutic implications from genetic test results. More...
18 Sep 2019
Image: This infographic illustrates the connection between the brain, central nervous system and other organs and how they interact with a person\'s gut microbes to show different patterns from people with high blood pressure plus depression; high blood pressure without depression; depression with healthy blood pressure; or healthy subjects without depression or high blood pressure (Photo courtesy of Professor Bruce R. Stevens, PhD).

Gut Bacteria Linked to High Blood Pressure and Depression

The microbiome is the genetic material of all the microbes, bacteria, fungi, protozoa and viruses that live on and inside the human body. The number of genes in all the microbes in one person's microbiome is 200 times the number of genes in the human genome. More...
17 Sep 2019
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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