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Microbiology

Image: Test strips of IMMY Cryptococcal Antigen Lateral Flow Assay kit (LFA) (Photo courtesy of the Institute for Medical Research, Kuala Lumpur, Malaysia).

Lateral Flow RPA Assay Developed for Cryptococcus in CSF

The most common presentations of cryptococcosis are meningitis and meningoencephalitis. Cryptococcal meningitis (CM) is a subacute meningoencephalitis and the most common cause of adult meningitis with very high mortality rates as well as vision and hearing loss in survivors. More...
06 Mar 2019
Image: A diagram of how human anti-fungal Th17 immunity and pathology rely on cross-reactivity against Candida albicans (Photo courtesy of the University of Kiel).

Intestinal Mucosa Fungus Can Affect Lung Health

The composition of the microbiome, the countless bacteria, fungi and viruses that colonize our body surface, skin, intestines or lungs, makes a decisive contribution to human health or disease. However, biological mechanisms that cause inflammations in the microbiome are still largely unknown. More...
04 Mar 2019
Image: Unnecessary testing for urinary tract infections can be significantly reduced (Photo courtesy of Nicole Wetsman).

Unnecessary Testing for UTIs Significantly Reduced

Tests to detect urinary tract infections (UTI) often are performed routinely in hospitals, even when patients do not have symptoms. Such testing "just to be safe" can return results that lead doctors to prescribe antibiotics when there is little to no evidence to warrant such treatment. More...
04 Mar 2019
Image: The T8 Isothermal Diagnostics Instrument provides quantitative and qualitative results for molecular diagnostic isothermal assay applications (Photo courtesy of Axxin).

Buruli Ulcer Pathogen Detected by Isothermal RPA Assay

Buruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans. The pathogenesis of BU is linked to the production of a polyketide toxin known as mycolactone, which is cytotoxic and has immunomodulatory properties and presents as nodules, plaques, ulcers and edema. More...
28 Feb 2019
Image: A male and a female gametocyte of Plasmodium falciparum (Photo courtesy of Professor David Baker).

Saliva-based Test Detects Infectious Subclinical Malaria

Low-density subclinical infection with Plasmodium falciparum among defined population subsets has been shown to be an important but cryptic facet of malaria transmission. Typically, these individuals are not readily detected by currently available point-of-need (PON) rapid diagnostic tests (RDTs) or microscopy. More...
27 Feb 2019
Image: Dr. Krishnan Chittur, PhD, chief technology officer and co-founder of GeneCapture, holds the prototype of the rapid infection test cartridge (Photo courtesy of GeneCapture).

Assay Targets Antibiotic Resistance with Pathogen Identification

A rapid diagnostic device has been developed to detect and identify the source of an infection in less than one hour. More...
18 Feb 2019
Image: A diagram of the 20-Gene Set Predictive of Progression to Severe Dengue study (Photo courtesy of Stanford University School of Medicine).

Dengue Severity Predicted by Gene Expression Signature

About 400 million individuals annually are infected with any of the four dengue virus (DENV) serotypes and although the majority of symptomatic individuals present with acute dengue fever, a fraction, between ∼5% to 20% of these patients progress to severe dengue infection. More...
14 Feb 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.