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Microbiology

Image: The ACL Top 550 hemostasis analyzer (Photo courtesy of Werfen).

Blood Clotting Causes Significant Mortality in COVID-19 Patients

Although the underlying pulmonary pathophysiology remains incompletely understood, severe COVID-19 infection is associated with a marked alveolar inflammatory cell infiltrate, together with a systemic cytokine storm response. More...
11 May 2020
Image: Photograph of the CARMEN microwell chip (Photo courtesy of Michael James Butts)

CRISPR-Based Microarray System Enables Massive Testing for Viral Pathogens

A novel microfluidic nucleic acid-based diagnostic system is capable of detecting a specific virus from a catalog of more than 160 human pathogens, including the COVID-19 coronavirus, simultaneously in more than 1,000 samples. More...
11 May 2020
Image: Salmonella are gram-negative, rod-shaped, facultative anaerobic bacteria. Newly developed sensitive and specific assays are able to detect different serotypes of Salmonella, paving the way for rapid serotyping directly from specimens (Photo courtesy of Public Health Image Library, [U.S.] Centers for Disease Control and Prevention)

A Series of Sensitive and Specific DNA-Based Assays Detects and Differentiates Salmonella Serotypes

A team of Australian researchers developed a series of sensitive and specific assays to detect and identify different serotypes (serovars) of Salmonella, a common cause of bacterial foodborne disease worldwide. More...
07 May 2020
Image: Antibody Detection Is Critical for COVID-19 Diagnosis (Photo courtesy of Minnesota Department of Health).

Antibody Detection Is Critical for COVID-19 Diagnosis

Accurate and fast diagnosis of the causative SARS CoV-2 is important to isolate the patients with COVID-19 timely and stop the epidemics, as well as save people's lives. Viral nucleic acid detection using real-time polymerase chain reaction (RT-PCR) assay, which has been developed and used for detection of SARS-CoV-2 rapidly, remains the standard diagnosis of COVID-19. More...
06 May 2020
Image: The positive results of Helicobacter pylori infection by the traditional Giemsa stain. White arrows indicate stained Helicobacter pylori (blue) that are attached to the brush border of the gastric foveolar epithelial cells (Photo courtesy of National Health Research Institutes).

Giemsa Stain Outperforms Urease Test for Helicobacter Pylori Diagnosis

More than 50% of the worldwide population is infected by Helicobacter pylori which is harbored in their upper gastrointestinal tract. Despite having chronic gastritis, most people infected by H. pylori are asymptomatic and have no specific clinical signs and symptoms. More...
05 May 2020
Image: The LightCycler 96 Instrument is a real-time PCR system for rapid cycling up to 96 samples (Photo courtesy of Roche Molecular Systems).

Scabies Detected by Molecular Methods in Skin Scrapings

Scabies caused by Sarcoptes scabiei mites, is a highly contagious parasitic disease characterized by intense itching which is aggravated at night. Infections by scabies mites result in various skin eruptions consisting of papules, nodules, vesicles, and excoriated eczematous lesions due to scratching. More...
29 Apr 2020
Image: The PHOMO Microplate Reader: the sophisticated optical design combined with the accurate plate transport system allows for high resolution scanning (29 points per well) to support agglutination assays (Photo courtesy of Autobio Diagnostics Co).

Urea Dissociation Tests Reduces SARS-CoV-2 IgM False-Positives

At present, the diagnosis of COVID-19 is mainly based on epidemiological history inquiry, laboratory testing, and chest radiology examination. Among these examinations, the detection of nucleic acid from SARS-CoV-2 is the direct evidence for COVID-19 diagnosis. More...
28 Apr 2020
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.