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Immunology

Image: The Triple TOF 5600+ mass spectrometer (Photo courtesy of SCIEX).

Proteomics Approach Used for Analyses of Breast Cancer

Accurate classification of breast tumors is vital for patient management decisions and enables more precise cancer treatment. Despite the progress achieved in early cancer diagnosis and therapy, many patients develop the deadly disease. More...
31 Jul 2019
Image: The LSRFortessa flow cytometer instrument (Photo courtesy of BD Biosciences).

Rare Inherited Enzyme Disorder Yields Insight into Fibrosis

Mammalian tissues and organs preserve their structural and functional homeostasis by means of their supportive connective tissue, a three-dimensional network of cells and extracellular matrix (ECM) with different topological characteristics depending on the organ/tissue in which it is embedded. More...
31 Jul 2019
Image: The Multiskan GO microplate spectrophotometer (Photo courtesy of Thermo Fisher Scientific).

Methods Evaluated to Detect Asymptomatic Visceral Leishmaniasis

Visceral leishmaniasis (VL) is caused by Leishmania infantum [synonymous L. chagasi] in the New World or L. donovani in the Old World, VL can be classified as an anthroponotic or zoonotic disease because it is transmitted between humans and others mammals, such as dogs. More...
24 Jul 2019
Image: A histopathology of nodular glomerulosclerosis in a patient with long-standing diabetes mellitus. Note the markedly thickened arteriole at the lower right, which is typical for the hyaline arteriolosclerosis that is seen in diabetic kidneys as well (Photo courtesy of University of Utah).

Collagen Biomarkers Clarify Prognosis of Diabetic Renal Complications

Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, is a chronic condition in which the pancreas produces little or no insulin. Insulin is a hormone needed to allow sugar (glucose) to enter cells to produce energy. More...
24 Jul 2019
Image: An immunohistochemical staining IL-17A expression in (A) M. mycetomatis, and (B) S. somaliensis. IL-17A staining was seen as a brown cytoplasmic staining in cells (Photo courtesy of University of Khartoum).

Immune Molecules Expressed Inside Mycetoma Lesions

Mycetoma is a persistent, progressive granulomatous inflammatory disease caused either by fungi or by bacteria. Characteristic of this disease is that the causative agents organize themselves in macroscopic structures called grains. These grains are surrounded by a massive inflammatory reaction. More...
24 Jul 2019
Image: An immunoglobulin G (IgG)-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis (Photo courtesy of Institut Pasteur).

Immunoglobulins and Neutrophils Play Unexpected Role in Anaphylaxis

Anaphylaxis may be brought about by various substances, including drugs (antibiotics or neuromuscular blocking agents), food and insect venom. Anaphylaxis is a hyperacute allergic reaction caused by an inappropriate immune response following the introduction of a usually harmless antigen into the body. More...
23 Jul 2019
Image: A scanning electron micrograph (SEM) of infectious particles of the avian H7N9 virus emerging from a cell (Photo courtesy of Medical Xpress).

T Cell Antibody and Memory in H7N9 Survivors Characterized

Avian influenza A (H7N9) is a subtype of influenza viruses that have been detected in birds in the past. This particular A (H7N9) virus had not previously been seen in either animals or people until it was found in March 2013 in China. More...
19 Jul 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.