Hematology
Diagnostic Assay Identifies Leukemic Stem Cells
Acute myeloid leukemia (AML) is the most common type of leukemia in adults. It is characterized by the pathological expansion of immature cells (myeloblasts) that invade the bone marrow and expand into the blood, affecting the production of the rest of the healthy cells. More...15 Jan 2020
Glycoprotein-Specific Direct Platelet Autoantibody Testing in Immune Thrombocytopenia
Autoantibodies directed against platelet glycoproteins have long been accepted as a major pathophysiologic mechanism in immune thrombocytopenia (ITP), but platelet autoantibody (PA) testing has previously shown poor sensitivity for ITP diagnosis. More...14 Jan 2020
Biomarker Predicts Prognosis in Acute Myeloid Leukemia Patients
Acute myeloid leukemia (AML) is the most prevalent adult acute leukemia, which is characterized by abnormal proliferation and the accumulation of immature myeloid precursor cells in the bone marrow, peripheral blood, and even some tissues, contributing to the destruction of the hematopoietic system. More...13 Jan 2020
Molecular Profiles, Microenvironment Signatures May Improve Lymphoma Prognosis
The tumor microenvironment includes surrounding blood vessels, immune cells, fibroblasts, signaling molecules, and the extracellular matrix that encapsulate the cancerous cells. The non-lymphoma cells lingering in the tumor's microenvironment, for example, can modify the effect of the mutations. More...09 Jan 2020
Immature Natural Killer Cells Predict Relapse After Cord Blood Transplantation
Umbilical cord blood transplantation (CBT) has become an accepted alternative treatment of patients with hematologic cancers or other disorders. Many of the disadvantages of CBT, including limited numbers of total nucleated cells, have been dealt with in significant ways, leading to marked reductions in the time to hematopoietic cell recovery. More...31 Dec 2019
Hypercoagulability Evaluated in New‐Onset Systemic Lupus Erythematosus Patients
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease that involves T cell, B cell, and dendritic cell dysfunction, as well as antinuclear autoantibody production. Several clinical and scientific studies of SLE indicate an increased risk of thrombosis in these cases. More...30 Dec 2019
Germline Genetic Testing Assesses Inherited Risk for Myeloid Malignancies
Inherited risk for hematologic malignancies was historically thought to be relatively rare; however, the increased use of next-generation sequencing has identified more patients with germline genetic mutations that are known to increase cancer risk. More...26 Dec 2019
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In Other News
Hepatic Dysfunction and Coagulopathy Quantified in Fatal Dengue Fever
Distinct Myelodysplastic Syndrome Subtypes Identified by Genomic, Transcriptomic Analysis
Fresh Red Blood Cells Transfusions No Better Than Older Ones
Single-Cell Analysis Uncovers Regulatory Program in Rare Leukemia
Autoimmunity Markers Prevalence Assessed in Immune Thrombocytopenia
TP53 Gene Promoter Methylation Impacts Chronic Lymphocytic Leukemia
Coagulation Function Explored for Gestational Diabetes Hemorrhage Risk
Hemophilia B Gene Increases Risk for Postpartum Bleeding
Acute Myeloid Leukemia Diagnosed by Convolutional Neural Networks
Next Generation Glycated Hemoglobin Assay Evaluated
Second Malignancy Risk Higher for Some Leukemia Survivors
Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants
Routine Blood Parameters Predict Invasive Aspergillosis Prognosis
Hematological Ratios Associated with Mortality in Pediatric Trauma Patients
Reference Intervals Established for Serum Ferritin in Chinese Adults
Measurable Residual Disease Assessed Post-Transplantation in Acute Lymphoblastic Leukemia
Allogeneic Transplantation Outcomes Compared in Sickle Cell Disease Patients
Biomarkers Analyzed for Central Nervous System Lymphoma
Specific Cytokines Are Significant Biomarkers for AML
Blood Monocyte Functions Altered in Parkinson's Disease
Two Different Mutations Identified as Cause of AML
Parkinson’s Gene Mutation Linked to Higher Risk of Leukemia
Human CRP-Levels Compared Using Point-of-Care Methods
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
