Hematology
TP53 Gene Promoter Methylation Impacts Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is a clonal disorder that results in the accumulation of morphologically mature-looking and immunologically incompetent lymphoid cells in the bone marrow, peripheral blood, and lymphatic tissues. More...11 Dec 2019
Coagulation Function Explored for Gestational Diabetes Hemorrhage Risk
Gestational diabetes mellitus (GDM) is characterized as glucose intolerance of any degree that begins or first diagnosed during pregnancy. It possesses a higher risk of hemorrhage, which may be caused by the coagulation dysfunction. More...10 Dec 2019
Hemophilia B Gene Increases Risk for Postpartum Bleeding
Pregnancy influences the levels of blood clotting factors. In healthy women, the activity of factor VIII (FVIII), the missing coagulation factor in hemophilia A, more than doubles in the third trimester and drops back to normal levels within days following delivery. Conversely, factor IX (FIX) activity, the clotting factor defective in hemophilia B, increases slightly or remains the same during normal pregnancy. More...09 Dec 2019
Acute Myeloid Leukemia Diagnosed by Convolutional Neural Networks
Every day, millions of single blood cells are evaluated for disease diagnostics in medical laboratories and clinics. Most of this repetitive task is still done manually by trained cytologists who inspect cells in stained blood smears and classify them into roughly 15 different categories. More...27 Nov 2019
Next Generation Glycated Hemoglobin Assay Evaluated
Diabetes mellitus is a pathological condition that affects all age groups worldwide. The percentage of glycated hemoglobin A1C (HbA1C) reflects the mean plasma glucose level over the previous 3 to 4 months for most individuals and can be used to diagnose type 2 diabetes. More...26 Nov 2019
Second Malignancy Risk Higher for Some Leukemia Survivors
Chronic lymphocytic leukemia (CLL) is the most common leukemia diagnosis in adults, with favorable outcomes in majority of patients and a 5-year survival of around 85%. A large proportion of CLL patients may never require treatment, requiring only ongoing surveillance. More...25 Nov 2019
Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants
A single normal cell randomly acquires a series of mutations that allows it to proliferate and to be transformed into a cancer cell (i.e., founding clone), which initiates tumor progression and recurrence. More...25 Nov 2019
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In Other News
Routine Blood Parameters Predict Invasive Aspergillosis Prognosis
Hematological Ratios Associated with Mortality in Pediatric Trauma Patients
Reference Intervals Established for Serum Ferritin in Chinese Adults
Measurable Residual Disease Assessed Post-Transplantation in Acute Lymphoblastic Leukemia
Allogeneic Transplantation Outcomes Compared in Sickle Cell Disease Patients
Biomarkers Analyzed for Central Nervous System Lymphoma
Specific Cytokines Are Significant Biomarkers for AML
Blood Monocyte Functions Altered in Parkinson's Disease
Two Different Mutations Identified as Cause of AML
Parkinson’s Gene Mutation Linked to Higher Risk of Leukemia
Human CRP-Levels Compared Using Point-of-Care Methods
Hematological Parameters Detect Patients with Acute VTE
Laser Incubator Developed for Rapid Blood Group Typing
Biomarker in Adolescence Linked to Early Mortality
Next-Gen Sequencing Matches Blood Group Antigens for Transfusion
Chronic Lymphocytic Leukemia Linked with Higher Melanoma Risk
Serum HMGB1 Levels Reflect Clinical Features of HLH
Genetics Affect Risk of Developing Factor VIII Inhibitors
Clinical Specificity of RBC Alloantibodies Studied in Pregnant Women
Toolkit Developed for Iron Deficiency in Pregnancy
Platelet Volume Related to Geriatric Patient In-Hospital Mortality
Hematology Analyzer Screens for Malaria in Clinical Setting
BRCA2 Mutations Linked to Pediatric Non-Hodgkin Lymphoma Risk
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.