Molecular Diagnostics
TP53 Gene Promoter Methylation Impacts Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is a clonal disorder that results in the accumulation of morphologically mature-looking and immunologically incompetent lymphoid cells in the bone marrow, peripheral blood, and lymphatic tissues. More...11 Dec 2019
Three Factors Distinguish MODY, a Rare Diabetes, in Youth
Identifying maturity-onset diabetes of the young (MODY) in pediatric populations close to diabetes diagnosis is difficult. Misdiagnosis and unnecessary insulin treatment are common. MODY is a monogenic, dominantly inherited form of diabetes that typically arises in adolescence or young adulthood, and accounts for 1%-4% of cases of pediatric diabetes. More...10 Dec 2019
Diagnosing Disease Conditions by Analyzing Plasma Protein Expression Patterns
A proof-of-concept study demonstrated that protein expression patterns in plasma samples were indicative of many different health issues, and that combining large-scale protein scanning with machine learning was a viable approach for the development of new diagnostic and prognostic tools. More...
09 Dec 2019
Genetic Architectures of Schizophrenia Compared in Different Populations
While the common genetic variants contributing to schizophrenia in East Asian individuals appear to broadly resemble those found in Europeans, polygenic risk scores (PRS) for the condition cannot necessarily be transferred from one population to the next. More...05 Dec 2019
Marker Panel Detects Early Liver Cancer with Increased Sensitivity
Several types of cancer can form in the liver. The most common type of liver cancer is hepatocellular carcinoma, which begins in the main type of liver cell (hepatocyte). Other types of liver cancer, such as intrahepatic cholangiocarcinoma and hepatoblastoma, are much less common. More...05 Dec 2019
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In Other News
Rare Genetic Variants Associated with Sudden Cardiac Death
CRISPR-based Electrochemical Biosensor Detects Disease-related MicroRNAs
Gene Panel Predicts Failure of Cutaneous Leishmaniasis Treatment
Genetic Locus with Unique Tandem Repeats Linked to Development of Late-onset Alzheimer’s Disease
Multiplex Panel Debuts for Multi-Drug Resistant Infection Screening
Non-coding Regions of the Genome in Microglia Linked to Alzheimer’s Disease Risk
Epigenetic DNA Biomarkers Pinpoint Infertile Men and Predict Potential Success of Treatment
LDL Subclasses Ratio Predicts Cardiovascular Disease Risk More Accurately than LDL-cholesterol Alone
MicroRNA Panel Distinguishes Benign Moles from Melanoma in the Eye
Mycobacterium Infection Found in Gastric Patients’ Stomachs
Novel, High-Accuracy Blood Test Can Screen for Multiple Cancers
Crohn's Disease-Associated Bacteria Tolerate Antibiotics
Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants
Aqueous Humor Is Superior to Blood to Diagnose Retinoblastoma
A Potential Point-of-Care Method for the Diagnosis of Sepsis
Novel Nanosensing Technologies Developed for Exosome Detection and Profiling
Blood Biomarkers Identify Individuals at Risk of Heart Attack or Stroke
Biomarker in Stools Helps to Diagnose Necrotizing Enterocolitis in Premature Babies
Early-Onset Alzheimer's Mutation Possibly Mitigated by APOE Variant
Project Set to Develop Algorithm Able to Accurately Predict and Detect Sepsis
Phoenix CPO Test Evaluated for Detection of Carbapenemase Producers
Rapid Fluorescence Fingerprinting Assay for Identification of Synthetic Cannabinoid Receptor Agonists
Newly Identified Biomarker Distinguishes Potentially Aggressive Meningiomas
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
