Molecular Diagnostics
Metastatic Gastric Cancer Outcomes Informed by Single-Cell Transcriptome Profiles
Peritoneal Carcinomatosis (PC) is a late stage manifestation of several gastrointestinal malignancies including appendiceal, colorectal, and gastric cancer. In PC, tumors metastasize to and deposit on the peritoneal surface and often leave patients with only palliative treatment options. More...21 Jan 2021
Alzheimer's Disease Subtypes Proposed from Brain Gene Expression Profiles
Alzheimer’s disease (AD) is the most common form of dementia in the elderly, estimated to affect more than 5.8 million individuals in the USA and more than 50 million worldwide, with almost half of individuals aged over 75 years. More...18 Jan 2021
Common Brain Malformation Traced to Its Genetic Roots
About one in 100 children has a common brain disorder called Chiari 1 malformation, but most of the time such children grow up normally and no one suspects a problem. However about one in 10 of those children, the condition causes headaches, neck pain, hearing, vision and balance disturbances, or other neurological symptoms. More...12 Jan 2021
Elevated Galectin-1 Levels in Sepsis Reflect Danger of Cytokine Storm Development
Increased concentration of the beta-galactoside-binding protein “galectin-1” in sera from human sepsis patients has been found to be a novel biomarker for cytokine storms that may occur in cases with runaway sepsis. More...11 Jan 2021
Next Generation Sequencing Developed for Monitoring of Mixed Chimerism
Hematopoietic stem-cell transplantation (HSCT) is the only curative treatment for patients with hematological malignant and non-malignant diseases. There are more than 50,000 stem cell transplants are carried out annually worldwide and the number is increasing. More...07 Jan 2021
Chitotriosidase Expression in Sarcoidosis Limited by Gene Expression
Sarcoidosis is a multisystem granulomatous disease which affects individuals worldwide of all ages irrespective of ethnicity or race. It is often recognized accidentally when a routine chest radiographic picture shows bilateral hilar lymphadenopathy. More...06 Jan 2021
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In Other News
Plasma Serglycin Levels Evaluated for Diabetic Retinopathy Diagnosis
Single-Cell Transcriptome Links Gut Development, Pediatric Crohn's Disease
Rare Genetic Variants Can Contribute to Ischemic Heart Failure
Osteopontin Linked to Progressive Lung Scarring in Scleroderma Patients
Next-Generation Sequencing Detects Residual Disease in Acute Lymphoblastic Leukemia
Distinct Mutation Patterns Identified in Appendiceal Cancer
Novel Classification System Identifies Prostate Cancer Patients Who May Benefit from Combined Immune and Radiation Therapies
Plasma Levels of N-terminal Tau Fragments Predict Likelihood of Cognitive Decline in Elderly Individuals
Gene Expression Signature Traces Nonalcoholic Fatty Liver Disease Progression
Rapid Decentralized Testing for Diagnosis of COVID-19
Microtubule Binding Region of Tau Protein Is a Biomarker for Diagnosis of Alzheimer’s Disease
Nanodiamonds Dramatically Boost Immunoassay Sensitivity
Some Phosphorylated Tau Proteins Indicate Alzheimer’s Disease Prior to Appearance of Cognitive Impairment
Rare Variants Associated with Blood Pressure Regulation
Fast Antibacterial Susceptibility Testing by Measuring Electron Transfer Metabolism
Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies
SARS-CoV-2 RNA Test Assessed Among Recovered COVID-19 Patients
Panel of Urinary Peptides Used to Diagnose Liver Fibrosis
Metagenomic Sequencing Quickly Identifies Pathogens in Body Fluids
Blood Biomarker Protein Correlates with Severity of Brain Damage in Stroke Patients
COVID-19 Lung Damage Caused by Persistence of Abnormal Cells
Levels of MicroRNAs in Saliva Are Diagnostic for Mild Traumatic Brain Injury
Methylated DNA Profiling Explored for Prenatal Testing Applications
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
