Molecular Diagnostics
Genetic Mutations Identified for Rare VEXAS Syndrome
VEXAS syndrome is a serious inflammatory condition which develops in men over 50, causing them to become very sick and fatigued, and can be fatal. It was originally thought to be rare, but a new study has identified genetic mutations which indicate that the disease is actually much more common. More...23 Mar 2021
Immune Cells in Cerebrospinal Fluid Predict Response to Immunotherapy
Immune checkpoint inhibitors including anti-PD1, anti-PD-L1, and anti-CTLA4, have shown significant clinical benefits in patients with progressive or metastatic solid tumors, including some brain metastasis. Notably, these immune-based therapies have improved outcomes for some of those suffering from lung cancer and melanoma. More...22 Mar 2021
Pediatric Pancreatic Cancer Diagnosed from cfDNA Fragments in Urine
Although rare, pancreatoblastoma is the most common pancreatic tumor of young children. Carcinoma of acinar cell origin has rarely been reported in older children. Ductal adenocarcinoma and its many variants are the most common pancreatic tumors in adults, but these are exceedingly rare in children. More...17 Mar 2021
Clonal Hematopoiesis and Recurrent Mutations Identified in Blood Cancers
Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by detectable hematopoietic-associated gene mutations in a person without evidence of hematologic malignancy. Somatic mutations at hotspots (genetic loci observed to be frequently mutated across cancer patients) often drive or contribute to cancer pathogenesis. More...16 Mar 2021
Liquid Biopsy Technique Detects Circulating Tumor Cells in Patients with Non-Small Cell Lung Cancer
A liquid biopsy technique based on hexokinase-2, a key enzyme in glucose metabolism, is able to detect circulating tumor cells (CTCs) in patients with non-small cell lung cancer (NSCLC). More...16 Mar 2021
Analysis of Urinary Exosome RNA Can Diagnose Kidney Transplant Rejection
A panel of mRNA signatures derived from urinary exosomes was shown to be a powerful and noninvasive tool to screen for the body’s rejection of a kidney allograft (a transplant from a genetically non-identical donor). More...15 Mar 2021
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Pulse-Controlled Amplification Tested for Infectious Disease Diagnostics
22-Gene Genomic Classifier Validated in Recurrent Prostate Cancer Patients
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Proteogenomic and Metabolomic Studies Characterize Human Glioblastoma
Study Confirms Value of the MyProstateScore Urine Test for Prostate Cancer Screening
Next Generation Sequencing Finds More Gene Mutations for Leukemia
Exome Sequencing Identified Pathogenic Variants in Cerebral Palsy Patients
Analysis of Cell-free DNA in the Blood May Replace Examination of Biopsy Specimens for Disease Diagnosis
NanoString Technology Modernizes Liposarcoma Diagnostics
TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
Prolonged Maternal Zika Viremia Evaluated for Adverse Perinatal Outcomes
Early Plasma Biomarkers Discovered for Alzheimer's Disease
TAP1 Gene Polymorphisms Associated with Recurrent Respiratory Papillomatosis
Liquid Biopsy Allows Monitoring of COVID-19 Damage to Cells, Tissues, and Organs
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
