We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Wheaton Acquires Bioreactor Flask Line from Wilson Wolf

By LabMedica International staff writers
Posted on 25 Jul 2012

Wheaton Industries (Millville, NJ, USA) has acquired the CELLine bioreactor flask line for antibody and protein production from Wilson Wolf Manufacturing Corp. (New Brighton, MN, USA).

Wheaton has acquired the CELLine dual membrane, cell culture flasks from Wilson Wolf Manufacturing Corp. Wheaton has also entered into a long term strategic partnership with Wilson Wolf Manufacturing for additional product development in high density cell culture devices for the production of concentrated, cell secreted products.

CELLine flasks are easy to implement and are known worldwide for small-scale suspension and adherent cultures. The CELLine dual membrane bioreactor system is designed as a humane alternative to hybridoma culture in the peritoneal cavity of mice, also known as the ascites method.

The flasks enhance small-scale bioproduction for antibody and protein generation. Conventional in vivo or in vitro cell culture methods can be labor-intensive, result in low cell density, and require significant purification. The CELLine flasks address these three areas of limitation in a single use, repeatable technology. CELLine flasks are ready-to-use and disposable, and generate high cell density and high product concentration, while considerably reducing culture and processing time.

“We are excited to bring this innovative, high growth technology to Wheaton and to our customers around the world, enabling our customers’ life’s work. These products, combined with the existing Wheaton portfolio, support the advancement of antibody and protein research, development and production,” says Stephen R. Drozdow, president of Wheaton. “We are also proud to have an ongoing partner with Wilson Wolf, for collaboration and further advancement of cell culture products,” he added.

Related Links:
Wheaton Industries
Wilson Wolf Manufacturing

Visit expo >

Gold Member

Hematology Analyzer

Medonic M32B

Gold Member

Collection and Transport System

PurSafe Plus®

HBV DNA Test

GENERIC HBV VIRAL LOAD VER 2.0

New

Gold Member

Ketosis and DKA Test

D-3-Hydroxybutyrate (Ranbut) Assay

Latest BioResearch News

Channels

Clinical Chemistry

view channel

Mismatch Between Two Common Kidney Function Tests Indicates Serious Health Problems

Creatinine has long been the standard for measuring kidney filtration, while cystatin C — a protein produced by all human cells — has been recommended as a complementary marker because it is influenced... Read more

Image: Schematic diagram of esophageal cancer cell identification research process (Photo courtesy of GE Dianlong)

VOCs Show Promise for Early Multi-Cancer Detection

Early cancer detection is critical to improving survival rates, but most current screening methods focus on individual cancer types and often involve invasive procedures. This makes it difficult to identify... Read more

Image: Portable Raman spectroscopy could help detect kidney disease at POC (Photo courtesy of Shutterstock)

Portable Raman Spectroscopy Offers Cost-Effective Kidney Disease Diagnosis at POC

Kidney disease is typically diagnosed through blood or urine tests, often when patients present with symptoms such as blood in urine, shortness of breath, or weight loss. While these tests are common,... Read more

Image: Mesoporous gold nanoparticles have unique biosensing capabilities (Photo courtesy of The University of Queensland)

Gold Nanoparticles to Improve Accuracy of Ovarian Cancer Diagnosis

Ovarian cancer is considered one of the deadliest cancers, in part because it rarely shows clear symptoms in its early stages, and diagnosis is often complex. Current approaches make it difficult to accurately... Read more

Molecular Diagnostics

view channel

Liquid Biopsy Test to Enable Earlier Diagnosis of Numerous Cancer Types

Routine screening currently covers only a handful of cancers, leaving most cases detected after symptoms appear—often at advanced stages when outcomes are poorer. A new study now suggests that adding a... Read more

Image: A family history of heart disease is linked to a specific protein pattern in the blood (Photo courtesy of Adobe Stock)

Blood Protein Profile Indicates Early-Onset Coronary Heart Disease

People with a family history of early-onset coronary heart disease often face a higher risk despite normal cholesterol or blood pressure, and current screening tools don’t fully explain why.... Read more

New DNA Test Tracks Spread of Parasitic Disease from Single Sample

Leishmaniasis remains a major challenge for veterinary and public health systems, largely because its transmission involves multiple sand fly species and a wide range of animal hosts. Understanding these... Read more

Hidden Blood Biomarkers to Revolutionize Diagnosis of Diabetic Kidney Disease

Diabetic kidney disease often develops silently, and many patients are diagnosed only after irreversible damage has occurred. Late diagnosis frequently leads to complications affecting the kidneys, heart,... Read more

Hematology

view channel

Platelet Activity Blood Test in Middle Age Could Identify Early Alzheimer’s Risk

Early detection of Alzheimer’s disease remains one of the biggest unmet needs in neurology, particularly because the biological changes underlying the disorder begin decades before memory symptoms appear.... Read more

Image: Sickle cell disease patients with higher levels of RMVs, AMVs, and EMVs were found to have more severe disease (Photo courtesy of Adobe Stock)

Microvesicles Measurement Could Detect Vascular Injury in Sickle Cell Disease Patients

Assessing disease severity in sickle cell disease (SCD) remains challenging, especially when trying to predict hemolysis, vascular injury, and risk of complications such as vaso-occlusive crises.... Read more

ADLM’s New Coagulation Testing Guidance to Improve Care for Patients on Blood Thinners

Direct oral anticoagulants (DOACs) are one of the most common types of blood thinners. Patients take them to prevent a host of complications that could arise from blood clotting, including stroke, deep... Read more

Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage

Postpartum hemorrhage, severe bleeding after childbirth, remains one of the leading causes of maternal mortality worldwide, yet many of these deaths are preventable. Standard care can be hindered by delays... Read more

Immunology

view channel

Image: The labyrinth chip could one day help doctors look for aggressive, stem-like cancer cells in patient blood (Photo courtesy of Joseph Xu/Michigan Engineering)

Chip Captures Cancer Cells from Blood to Help Select Right Breast Cancer Treatment

Ductal carcinoma in situ (DCIS) accounts for about a quarter of all breast cancer cases and generally carries a good prognosis. This non-invasive form of the disease may or may not become life-threatening.... Read more

Image: The new liquid biopsy model can predict patient response to immune checkpoint therapies (Photo courtesy of 123RF)

Blood-Based Liquid Biopsy Model Analyzes Immunotherapy Effectiveness

Immunotherapy has revolutionized cancer care by harnessing the immune system to fight tumors, yet predicting who will benefit remains a major challenge. Many patients undergo costly and taxing treatment... Read more

Image: The research provides the first detailed view of how immune cells expand during cancer treatment and how this process can be restored (Photo courtesy of Shutterstock)

Signature Genes Predict T-Cell Expansion in Cancer Immunotherapy

Modern cancer immunotherapies rely on the ability of CD8⁺ T cells to rapidly multiply within tumors, generating the immune force needed to eliminate cancer cells. However, the biological triggers behind... Read more

Molecular Microscope Diagnostic System Assesses Lung Transplant Rejection

Lung transplant recipients face a significant risk of rejection and often require routine biopsies to monitor graft health, yet assessing the same biopsy sample can be highly inconsistent among pathologists.... Read more

Microbiology

view channel

Image: Development of targeted therapeutics and diagnostics for extrapulmonary tuberculosis at University Hospital Cologne (Photo courtesy of Michael Wodak/Uniklinik Köln)

Blood-Based Molecular Signatures to Enable Rapid EPTB Diagnosis

Extrapulmonary tuberculosis (EPTB) remains difficult to diagnose and treat because it spreads beyond the lungs and lacks easily accessible biomarkers. Despite TB infecting 10 million people yearly, the... Read more

Image: The rapid diagnostic test is being piloted across three UK hospitals (Photo courtesy of Imperial College Healthcare)

15-Minute Blood Test Diagnoses Life-Threatening Infections in Children

Distinguishing minor childhood illnesses from potentially life-threatening infections such as sepsis or meningitis remains a major challenge in emergency care. Traditional tests can take hours, leaving... Read more

High-Throughput Enteric Panels Detect Multiple GI Bacterial Infections from Single Stool Swab Sample

Gastrointestinal (GI) infections are among the most common causes of illness worldwide, leading to over 1.7 million deaths annually and placing a heavy burden on healthcare systems. Conventional diagnostic... Read more

Image: Sugar fingerprints open new possibilities for faster and more reliable diagnosis of fungal infections (Photo courtesy of 123RF)

Fast Noninvasive Bedside Test Uses Sugar Fingerprint to Detect Fungal Infections

Candida bloodstream infections are a growing global health threat, causing an estimated 6 million cases and 3.8 million deaths annually. Hospitals are particularly vulnerable, as weakened patients after... Read more

Pathology

view channel

Image: Using the approach, the team visualized intricate neuronal networks across full human brain sections (Photo courtesy of Marios Georgiadis)

Simple Optical Microscopy Method Reveals Hidden Structures in Remarkable Detail

Understanding how microscopic fibers are organized in human tissues is key to revealing how organs function and how diseases disrupt them. However, these fiber networks have remained difficult to visualize... Read more

Image: Overview of hydrogel-based direct EV isolation and fabrication and porosity characterization of meso-macroporous hydrogel particles (Junbeom Kim et al., Nature Nanotechnology, 2025. DOI: 10.1038/s41565-025-02011-1)

Hydrogel-Based Technology Isolates Extracellular Vesicles for Early Disease Diagnosis

Isolating extracellular vesicles (EVs) from biological fluids is essential for early diagnosis, therapeutic development, and precision medicine. However, traditional EV-isolation methods rely on ultra... Read more

Image: The AI tool could make skin cancer diagnosis more accurate and equitable across all skin tones (Photo courtesy of 123RF)

AI Tool Improves Accuracy of Skin Cancer Detection

Diagnosing melanoma accurately in people with darker skin remains a longstanding challenge. Many existing artificial intelligence (AI) tools detect skin cancer more reliably in lighter skin tones, often... Read more

Image: The three-panel image shows how BRM (birefringence microscopy) maps myelin and reveals injury (yellow arrow) (Photo courtesy of AJ Gray et al., Neurophotonics (2025). DOI: 10.1117/1.NPh.12.4.045006)

Highly Sensitive Imaging Technique Detects Myelin Damage

Damage to myelin—the insulating layer that helps brain cells function efficiently—is a hallmark of many neurodegenerative diseases, age-related decline, and traumatic injuries. However, studying this damage... Read more

Technology

view channel

Image: The technology can diagnose head and neck cancer early with a drop of saliva (Photo courtesy of Adobe Stock)

AI Saliva Sensor Enables Early Detection of Head and Neck Cancer

Early detection of head and neck cancer remains difficult because the disease produces few or no symptoms in its earliest stages, and lesions often lie deep within the head or neck, where biopsy or endoscopy... Read more

Image: The screen-printed electrochemical sensor (Photo courtesy of UT Dallas)

AI-Powered Biosensor Technology to Enable Breath Test for Lung Cancer Detection

Detecting lung cancer early remains one of the biggest challenges in oncology, largely because current tools are invasive, expensive, or unable to identify the disease in its earliest phases.... Read more

AI Model Achieves Breakthrough Accuracy in Ovarian Cancer Detection

Early diagnosis of ovarian cancer remains one of the toughest challenges in women’s health. Traditional tools such as the Risk of Ovarian Malignancy Algorithm (ROMA) can struggle to distinguish between... Read more

Image: The device costs USD 2.19 per unit (Photo courtesy of Amanda H. Imamura/Sci Illustrations)

Portable Biosensor Diagnoses Psychiatric Disorders Using Saliva Samples

Early diagnosis of psychiatric disorders such as depression, schizophrenia, and bipolar disorder remains one of medicine’s most pressing challenges. Current diagnostic methods rely heavily on clinical... Read more

Industry

view channel

Abbott Acquires Cancer-Screening Company Exact Sciences

Abbott (Abbott Park, IL, USA) has entered into a definitive agreement to acquire Exact Sciences (Madison, WI, USA), enabling it to enter and lead in fast-growing cancer diagnostics segments.... Read more

$Image: Freenome will evaluate Roche\'s forthcoming SBX technology for future development applications (Photo courtesy of Roche)$

Roche and Freenome Collaborate to Develop Cancer Screening Tests

Roche (Basel, Switzerland) and Freenome (Brisbane, CA, USA have entered into a strategic collaboration to commercialize Freenome's cancer screening technology in international markets.... Read more

Co-Diagnostics Forms New Business Unit to Develop AI-Powered Diagnostics

Co-Diagnostics, Inc. (Salt Lake City, UT, USA) has formed a new artificial intelligence (AI) business unit to integrate the company's existing and planned AI applications into its Co-Dx Primer Ai platform.... Read more

Qiagen Acquires Single-Cell Omics Firm Parse Biosciences

QIAGEN (Venlo, Netherlands) has entered into a definitive agreement to fully acquire Parse Biosciences (Seattle, WA, USA), a provider of scalable, instrument-free solutions for single-cell research.... Read more