Swift Biosciences Launches Normalase Amplicon Panel (SNAP) SARS-CoV-2 Kit
By LabMedica International staff writers Posted on 29 May 2020 |
Image: Swift Normalase Amplicon Panel (SNAP) SARS-CoV-2 kit (Photo courtesy of Swift Biosciences, Inc.)
Swift Biosciences, Inc. (Ann Arbor, MI, USA), which focuses on commercialization of DNA and RNA library preparation kits for Next-Generation Sequencing (NGS), has released its Swift Normalase Amplicon Panel (SNAP) SARS-CoV-2 kit.
Targeting the full viral genome in a single tube reaction with a rapid two-hour workflow, Swift's assay enables research and surveillance activities by accommodating the low viral copy titers found in clinical specimens. The two-round PCR kit supports high throughput processing by converting and enriching viral cDNA into multiplexed, NGS-ready libraries.
Unlike competing amplicon enrichment workflows that require subsequent NGS library construction, Swift's NGS assay is a straight two-round amplicon PCR that adds adapters directly without a secondary library construction. It works with samples that fail other methods with high qRT-PCR Ct values, while providing complete genome coverage.
Swift's new SNAP workflow offers Illumina-compatible index combinations for processing up to 384 samples per sequencing run and generate libraries that are flexible to conventional library quantification methods, as well as Swift Normalase to support increased throughput and scalability.
"Our new SNAP technology leverages Swift's patented multiplex PCR approach to target and amplify the entire 30 kb viral genome in a single tube reaction, which maximizes genome coverage and yields from as few as 10 viral copies," said Drew McUsic, PhD, Swift's Director of Product Management. "Our collaborators at NYU and University of Washington have demonstrated high sensitivity and the ability to track viral mutations with an NGS workflow that doesn't substantially increase time or labor demands compared to qRT-PCR."
Related Links:
Swift Biosciences, Inc.
Targeting the full viral genome in a single tube reaction with a rapid two-hour workflow, Swift's assay enables research and surveillance activities by accommodating the low viral copy titers found in clinical specimens. The two-round PCR kit supports high throughput processing by converting and enriching viral cDNA into multiplexed, NGS-ready libraries.
Unlike competing amplicon enrichment workflows that require subsequent NGS library construction, Swift's NGS assay is a straight two-round amplicon PCR that adds adapters directly without a secondary library construction. It works with samples that fail other methods with high qRT-PCR Ct values, while providing complete genome coverage.
Swift's new SNAP workflow offers Illumina-compatible index combinations for processing up to 384 samples per sequencing run and generate libraries that are flexible to conventional library quantification methods, as well as Swift Normalase to support increased throughput and scalability.
"Our new SNAP technology leverages Swift's patented multiplex PCR approach to target and amplify the entire 30 kb viral genome in a single tube reaction, which maximizes genome coverage and yields from as few as 10 viral copies," said Drew McUsic, PhD, Swift's Director of Product Management. "Our collaborators at NYU and University of Washington have demonstrated high sensitivity and the ability to track viral mutations with an NGS workflow that doesn't substantially increase time or labor demands compared to qRT-PCR."
Related Links:
Swift Biosciences, Inc.
Latest COVID-19 News
- New Immunosensor Paves Way to Rapid POC Testing for COVID-19 and Emerging Infectious Diseases
- Long COVID Etiologies Found in Acute Infection Blood Samples
- Novel Device Detects COVID-19 Antibodies in Five Minutes
- CRISPR-Powered COVID-19 Test Detects SARS-CoV-2 in 30 Minutes Using Gene Scissors
- Gut Microbiome Dysbiosis Linked to COVID-19
- Novel SARS CoV-2 Rapid Antigen Test Validated for Diagnostic Accuracy
- New COVID + Flu + R.S.V. Test to Help Prepare for `Tripledemic`
- AI Takes Guesswork Out Of Lateral Flow Testing
- Fastest Ever SARS-CoV-2 Antigen Test Designed for Non-Invasive COVID-19 Testing in Any Setting
- Rapid Antigen Tests Detect Omicron, Delta SARS-CoV-2 Variants
- Health Care Professionals Showed Increased Interest in POC Technologies During Pandemic, Finds Study
- Set Up Reserve Lab Capacity Now for Faster Response to Next Pandemic, Say Researchers
- Blood Test Performed During Initial Infection Predicts Long COVID Risk
- Low-Cost COVID-19 Testing Platform Combines Sensitivity of PCR and Speed of Antigen Tests
- Finger-Prick Blood Test Identifies Immunity to COVID-19
- Quick Test Kit Determines Immunity Against COVID-19 and Its Variants