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Pathology

Image: The QDx Vit. D test is designed for the determination of Vitamin D in whole blood. The test delivers a qualitative result from a finger prick sample of 20 µL within 10 minutes (Photo courtesy of DiaSys).

Vitamin D Levels Linked to Colorectal Cancer Risk

Experimental and epidemiological studies suggest a protective role for vitamin D in colorectal carcinogenesis, but evidence is inconclusive. Circulating 25-hydroxyvitamin D (25(OH)D) concentrations that minimize risk are unknown. More...
27 Jun 2018
Image: The QuantStudio6 Flex real-time PCR system (Photo courtesy of Thermo Fisher Scientific).

Vaginal Bacteria Linked to Cervical Cancer

High-risk human papillomavirus (HPV) infection is a well-established risk factor for cervical cancer, but there are likely other factors within the local microenvironment that contribute to cervical carcinogenesis. More...
27 Jun 2018
Image: A scanning electron micrograph (SEM) of a prostate cancer cell captured on frosted slide with silica nanowires (Photo courtesy of the American Chemical Society).

Biochip Developed to Detect Prostate Cancer Cells

In men with prostate cancer, some tumor cells exit the prostate gland and circulate in the blood. Detecting these cells could enable diagnosis at an earlier stage or help doctors assess whether treatment is effective. More...
20 Jun 2018
Image: Mycobacterium chimaera colonies growing on agar; the infections can cause serious injury, including pneumonia and death. Of particular concern is that patients infected with M. chimaera may not develop symptoms and signs of infection for months to years after initial exposure, making the infections difficult to detect and diagnose (Photo courtesy of the CDC).

Post-Cardiac Surgery Infection Associated with Different Diseases

Mycobacterium chimaera infection following cardiac surgery, due to contaminated cardiopulmonary bypass heater-cooler units (HCUs), has been reported worldwide. However, the spectrum of clinical disease remains poorly understood. More...
19 Jun 2018
Image: An endometrial carcinoma showing loss of nuclear expression of MSH2. The lymphocytes and stromal cells should stain positive and represent an internal positive control (Photo courtesy of Memorial Sloan Kettering Cancer Center).

MSI Tumor Analysis Implicates Lynch Syndrome in Cancer Types

A new pan-cancer analysis suggests that there may be a benefit to doing germline testing for Lynch syndrome in advanced cancer patients who have high microsatellite instability (MSI) in their tumors. More...
19 Jun 2018
Image: Testosterone/estradiol ratio and the risk of cardiovascular disease, coronary heart disease and heart failure (HF) in post-menopausal women (Photo courtesy of Johns Hopkins Medicine).

Hormone Levels Alter CVD Risk in Older Women

Higher androgen and lower estrogen levels are associated with cardiovascular disease (CVD) risk factors in women; however, studies on sex hormones and incident CVD events in women have yielded conflicting results. More...
13 Jun 2018
Image: A photomicrograph of breast cancer cells in purple surrounded by healthy tissue in pink (Photo courtesy of US National Institute of Health).

Hereditary Breast Cancer Tests Double Detection Rate

Germline genetic testing in patients newly diagnosed with cancer has the potential to reduce disease burden through secondary prevention and targeted therapies. There is a prerequisite to understand how genetic testing is being integrated into practice for patients newly diagnosed with cancer and the impact of results on treatment decisions. More...
23 May 2018
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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