Pathology

Proteomics Profile Early Detection Ovarian Cancer
High-grade ovarian cancer (HGOC) is the leading cause of mortality from gynecological malignancies, due to diagnosis at a metastatic stage. Current screening options fail to improve mortality due to the absence of early-stage-specific biomarkers. More...26 Mar 2019

Oral Bacteria Linked to More Aggressive Tumors
Pancreatic cystic neoplasms (PCN) are increasingly detected in the general population. They comprise a clinically challenging entity with potential to progress to invasive cancer. The disease is often discovered late, which means that in most cases the prognosis is poor. More...26 Mar 2019

Five-Gene Signature Predicts Survival from Renal Cell Carcinoma
Papillary renal cell carcinomas include type 1 lesions, which are characterized by small cells in single layers and scanty cytoplasm and type 2 lesions, which are distinguished by larger cells, pseudo-stratified nuclei, and voluminous eosinophilic cytoplasm. More...20 Mar 2019

EBUS More Reliable Than Histology for Cancer Diagnoses
Radial probe endobronchial ultrasound (EBUS) is a minimally invasive procedure that improves localization of peripheral pulmonary lesions. Cytology samples of the suspect lesion site collected by radial EBUS bronchoscopy provides good diagnostic sensitivity estimated at 73%, whereas histology does not definitely diagnose malignancy in approximately 20% cases. More...20 Mar 2019

Liquid Biopsy Proves Effective as Biopsy for NSCLC
Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC). NSCLC accounts for about 85% of all lung cancers. As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small cell carcinoma. More...13 Mar 2019

New Microfluidics Device Detects Cancer Cells in Blood
The ability to successfully isolate cancer cells is a crucial step in enabling liquid biopsy where cancer could be detected through a simple blood draw. This would eliminate the discomfort and cost of tissue biopsies, which use needles or surgical procedures as part of cancer diagnosis. More...12 Mar 2019
In Other News
Blood Test Predicts Kidney Transplant Rejection
Immunohistochemical Stain Facilitates cHL Diagnosis
Cervical Microbes Potentially Tied to Infections and Lesions
Genetic Defect Linked to Pediatric Liver Disease
Gastric Cancer Analysis Identifies Four Subtypes
Gene Missense Variant Associated with Crohn's Disease
MicroRNAs Provide Clues in Primary CNS Lymphoma
Atrophic Gastritis Prevalence Determined by Serological Evidence
Genetic Causes of Salivary Gland Carcinoma Discovered
Microbiome Helps Identify Patients with Early-Stage Cancer
Blood Test Detects Brain Damage Years before Symptoms
DNA Methylation Test Detects Early Aggressive Prostate Cancer
CSF Liquid Biopsy Sequencing Tracks Glioma Evolution
Bacterial Pathogen Discovered in Brains of Alzheimer's Patients
Simple Inexpensive Test Screens for Esophageal Cancer
Blood Test Improves Detection of Severe Transplant Rejection
Tumor Mutational Load Predicts Survival Post-Immunotherapy
Blood Test Diagnoses Pancreatic Cancer Disease Earlier
Retina Protein Antibodies Used As Kidney Cancer Marker
Molecular Prognostic Biomarker Found for CNS Lymphoma
Gene-Based Risk Scores Predicts Alcoholic Cirrhosis
Prognostic Signature Described in HPV-Positive Cell Carcinomas
Genetic Methods Rapidly Diagnoses Huntington's Disease
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.







