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Pathology

$Image: An example of a TaqMan Low Density Array card; each well contains a specific miRNA forward primer, a specific miRNA TaqMan probe, and a reverse \"tail\" primer (Photo courtesy of Dana-Farber Cancer Institute).$

Molecular Blood Test Developed for Kidney Cancer

Kidney cancer is usually caught because of the symptoms a patient develops, but it is also possible for kidney cancer to be asymptomatic, with tumors growing quite large before causing pain or other noticeable problems. More...
29 Aug 2017

Image: The QuantStudio 12K Flex system is a highly flexible, comprehensive real-time PCR platform (Photo courtesy of Thermo Fisher Scientific).

Gene Expression Profiling Validated for Uveal Melanoma

Uveal melanoma is a cancer of the eye involving the iris, ciliary body, or choroid (collectively referred to as the uvea). Tumors arise from the pigment cells (melanocytes) that reside within the uvea giving color to the eye. More...
29 Aug 2017

$Image: A scanning electron micrograph (SEM) showing T cells surrounding a breast cancer cell. Testing for immune \'hotspots\' can predict the risk that breast cancer will return (Photo courtesy of Sebastian Kaulitzki.$

Immune Infiltration Test Predicts Cancer Relapse Risk

Estrogen receptor-positive (ER+) subtype accounts for about 80% of all breast cancers, the most common cancer in women. At diagnosis, the majority of ER+ patients have a good prognosis if treated with endocrine therapy. More...
24 Aug 2017

Image: A histologic section of a colonic adenoma containing invasive carcinoma (Photo courtesy of Dr. Mauro Risio).

New Molecular Test Identifies Colorectal Cancer

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide, with more than 600,000 deaths each year. Among individuals undergoing treatment for the disease, recurrence occurs in 30% to 50% of all cases. The majority of these cases present in the first two to three years following initial diagnosis and treatment. More...
23 Aug 2017

Preoperative Bacteriuria Unconnected to Joint Infection

Patients who undergo elective joint replacement are traditionally screened and treated for preoperative bacteriuria in order to prevent periprosthetic joint infection (PJI), but more recently, this practice has been questioned. More...
22 Aug 2017

Image: The model illustrates clinical implications of BCBM CTC screening method for brain micro-metastasis before they become detectable by MRI. BCBM-associated CTCs can be used as a tool to evaluate responses to therapy for BCBM patients (Photo courtesy of Houston Methodist).

Blood Test Detects Brain Metastases While Treatable

A blood test is being generated that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response to therapy in real time. More...
16 Aug 2017

New Device Provides Better Biopsies for Cancer Testing

In a study comparing a new frictional fabric brush versus the currently used sharp scraper for endocervical curettage, the new device provided better tissue yield with less pain and discomfort. More...
14 Aug 2017

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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.