Pathology

Liquid Biopsy Lung Cancer Screening Method Developed
Genomic blood tests for cancer screening and early detection have become the focus of attention in the molecular diagnostic space, though most activity so far has been either toward pan-cancer screening tools, or in a few other specific tumor types like colorectal cancer, where tests hope to vie against colonoscopy and existing stool-based methods. More...09 Apr 2020

Potential Microbial Markers Identified for Cervical Pre-Cancer Progression
Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections. However, only a small percentage of high-risk (HR) HPV infections progress to cervical pre-cancer and cancer. The role of the cervicovaginal microbiome (CVM) in the natural history of HR-HPV has been investigated. More...08 Apr 2020

Early Prediction of Resistance to Tyrosine Kinase Inhibitors Reported
Epidermal growth factor receptor (EGFR) gene mutations that confer sensitivity to tyrosine kinase inhibitors (TKI) in non-small cell lung carcinomas paved the way for a precision medicine approach in this neoplastic form. More...31 Mar 2020

Urine-Based Kidney Transplantation Rejection Risk Assay Launched
For kidney transplant recipients, prompt and accurate detection of transplant rejection is vital for timely intervention. Unfortunately, the gold standard for diagnosis of rejection is kidney biopsy, an invasive procedure. More...30 Mar 2020

Genetic Testing Benefits Postmenopausal Women with Breast Cancer
Germline genetic testing for pathogenic variants (PVs) in cancer susceptibility genes after breast cancer diagnosis may inform cancer treatment, prevention, and testing of relatives. Postmenopausal women with breast cancer had a threefold higher prevalence of pathogenic variants in breast cancer-associated genes than their cancer-free counterparts. More...26 Mar 2020


Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
The concept of creating bespoke or personalized mutation panels to use for cancer recurrence detection and residual disease monitoring is not new at this point. Scientists began piloting these methods several years ago, initially tracking single mutations and then collections of alterations derived from tumor sequencing data. More...25 Mar 2020
In Other News
EGFR Mutation Assay Cartridges Evaluated
Prognostic Values of Platelet Parameters in Gynecological Tumors Patients
Combining Biomarkers Predicts Metastasis in Medullary Thyroid Carcinoma
Neurofibromatosis Gene and Breast Cancer Resistance to Hormone Therapy
Combined Biopsy Method Improves Prostate Cancer Diagnosis
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
Gut Bacteria Linked to Pulmonary Artery Hypertension
Blood Test Predicts Response to Immunotherapy in Metastatic NSCLC
Esophageal Cancer Precursor Detected by Electronic Nose Device
Heterogeneous Populations of Melanoma Circulating Tumor Cells Detected
Severe Strongyloidiasis Infection Reported in Kidney Transplant Recipients
Proteogenomic Characterization of Endometrial Carcinoma Analyzed
All-Digital Histopathology Attained by Infrared-Optical Hybrid Microscopy
Several Genes Linked to Long QT Syndrome Reappraised
Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans
Blood Test Lead to Earlier Detection of Gastrointestinal Cancers
Lung Cancer Liquid Biopsy Guides MRD-Directed Adjuvant Therapy
Single-Cell Sequencing Identifies Breast Cancer Risk
Heart Transplant Monitoring Test Validated
Microbiota’s Role Explored in Colorectal Cancer Among the Young
Technique Predicts Cancer Recurrence Risk for Melanoma Patients
Imaging Mass Cytometry Uncovers Novel Breast Cancer Subgroups
Ovarian Cancer Protein Contributes to Alzheimer`s Disease Neurodegeneration
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.








