Pathology
Tumor Microbiome Appears to Vary with Cancer Type
Bacteria are well-known residents in human tumors, but whether their presence is advantageous to the tumors or to the bacteria themselves has been unclear. Bacteria found within tumors were localized within both cancer cells and immune cells and that the bacterial composition varied according to tumor type. More...11 Jun 2020
Precision Oncology Confers Clinical Benefit in Relapsed Pediatric Cancer
The Individualized Therapy for Relapsed Malignancies in Childhood (INFORM) registry has been created to help develop precision medicine-based approaches and to analyze their effectiveness across high-risk relapsed or refractory pediatric cancers. More...08 Jun 2020
Saliva-Based Assay Developed for HPV-Driven Oropharyngeal Cancer
The incidence of high-risk human papillomavirus (HR-HPV−16, −18, −33) driven oropharyngeal cancer (OPC) is rapidly increasing in developed countries. HPV-driven OPCs have surpassed cervical cancer as the most common HPV-driven cancer in the USA. More...04 Jun 2020
Germline Risk Variants Found in Prostate Cancer Patients
Studies done over the past five years or so have unearthed pathogenic germline variants in some 12% to 17% of men with prostate cancer, and such alterations can impact everything from the treatment options available to them, to the management strategies used for other members of the same family. More...21 May 2020
Non-Invasive Blood Assay Can Detect Early Colorectal Cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). In general, colon cancer begins when healthy cells in the colon develop changes (mutations) in their DNA and as the cells accumulate, they form a tumor. More...21 May 2020
Microcytosis Is a Risk Marker of Cancer in Primary Care
Microcytosis is a term used to describe red blood cells that are smaller than normal. Anemia is when there are low numbers of properly functioning red blood cells in the body. In microcytic anemia, the body has fewer red blood cells than normal and those red blood cells it does have are also too small. More...20 May 2020
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In Other News
Rare Kidney Cancer Marked by Molecular Features
Blood Test Shows Promise for Predicting Cancer
Bacterial Blood Infections Tied to Heightened Colon Cancer Risk
Multicancer Blood Test Aids Screen for Cancer Guide Intervention
Biomarker Data Improves Risk Prediction for Pancreatic Cancer
Targeted Next-Generation Sequencing Validated for Lysosomal Storage Disorders Diagnosis
Genetic Alterations Analyzed in Pediatric Low-Grade Glioma
Molecular Differences Discovered Among Ovarian Cancer Subgroups
Important Genetic Mechanism Behind Inflammatory Bowel Disease Revealed
Genetic Risk Score Predicts Prostate Cancer Drug Response
Novel Inherited Mutation Predisposes Children to Medulloblastoma
Reactive Pneumocytes Identified by Distinctive Cytology
Susceptibility Gene Identified for Idiopathic Pulmonary Arterial Hypertension
Liquid Biopsy Lung Cancer Screening Method Developed
Potential Microbial Markers Identified for Cervical Pre-Cancer Progression
Early Prediction of Resistance to Tyrosine Kinase Inhibitors Reported
Urine-Based Kidney Transplantation Rejection Risk Assay Launched
Genetic Testing Benefits Postmenopausal Women with Breast Cancer
Multitarget Stool DNA Predicts Colorectal Neoplasia
Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
EGFR Mutation Assay Cartridges Evaluated
Prognostic Values of Platelet Parameters in Gynecological Tumors Patients
Combining Biomarkers Predicts Metastasis in Medullary Thyroid Carcinoma
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.