Pathology
Genetic Overlap Found for Ovarian Cancer Subtypes and Endometriosis (Cell Reports Medicine: University of Queensland)
A research team in Australia, the US, and the UK has delved into genetic ties between specific epithelial ovarian cancer (EOC) histotypes and endometriosis, a condition previously associated with enhanced EOC risk. More...22 Mar 2022
Single Cell Characterization Acral Melanoma Identifies Novel Targets for Immunotherapy
Acral melanoma is a rare subtype that represents roughly 3% of all melanoma cases. Unlike typical melanoma that occurs on sun-exposed skin, acral melanoma develops on the nonhair bearing skin of the soles, palm and nail beds. There is very little information known about the development of acral melanoma. More...16 Mar 2022
New Fluorescent DNA Label Reveals Nanoscopic Cancer Features
Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients and classification of future cancer risk. More...15 Mar 2022
AI Platform Identifies 99% of Positive Cancer Cases in Pathology Reports
A new artificial intelligence (AI) platform disrupts the manual and repetitive processes in healthcare to identify positive cancer diagnosis and incidental findings in real time, classify those diagnoses by primary site, and route those patients to cancer navigators and other staff to immediately start the cancer care journey. More...14 Mar 2022
Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases
Roughly one in every three children with a type of kidney cancer known as Wilms tumor, or nephroblastoma, carry germline alterations implicated in hereditary cancer risk, new research suggests — findings that have prompted more widespread genetic testing for Dutch children with the condition. More...08 Mar 2022
TTMV-HPV DNA Biomarker Predicts Recurrence of Oropharynx Cancer
A large, multi-institutional study demonstrates that a blood test to detect circulating tumor DNA can accurately predict recurrence of HPV-driven oropharyngeal cancer following treatment. Results also indicate that the biomarker test may detect recurrent disease earlier than imaging or other standard methods of post-treatment surveillance, allowing physicians to personalize treatment more quickly for patients whose cancer returns. More...03 Mar 2022
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In Other News
Two Important Cardiovascular Disease Risk Factors Operate Independently
Immunoassay Detects Pancreatic Cancer in People at High Risk
First-of-Its-Kind Clinical Blood Test Predicts Cancer Patient’s Response to ICI Immunotherapy
Tintin-Truncating Variant Associated With Late-Onset Dilated Cardiomyopathy
Histological Criteria Predicts Lymphoma Transformation in Bone Marrow Biopsies
Multi-Cancer Early Detection Test Could Become a Game-Changing Screening Tool
Early-Stage Prostate Cancer Detection Blood Test Granted FDA Breakthrough Designation
Cytosponge Biomarker Panel Prioritizes Endoscopic Barrett's Esophagus Surveillance
AI-Powered Diagnostic Platform Improves Early Detection of Esophageal Cancer in Patients with Barrett’s Esophagus
Novel Urinary miRNA Biomarker for Early Detection of Colorectal Cancer
New Method Determines Optimal Number of Pathologists Needed for Correct Disease Diagnosis
Diagnostic Value of Serum CHI3L1 in Hepatocellular Carcinoma Explored
Proteomic Noninvasive Biomarkers Associated with Sport-Related Concussions
Melanoma Test Offers Reassurance of Low Risk of Cancer Spread
Immuno-CRISPR Assay Helps Diagnose Early Kidney Transplant Rejection
Long Mononucleotide Repeat Markers Validated for Microsatellite Instability Detection
Natural Killer Cell-Associated Markers Investigated in Gastric Cancer
Association Between Helicobacter pylori With Nonalcoholic Fatty Liver Disease Assessed
Novel Protein Biomarkers Identified for Prostate Cancer Aggressiveness
Near Normal Aminotransferase Levels Reported in Alcoholic Cirrhosis Patients
Biomarker FR+CTC Explored for Breast Cancer Diagnosis
Tissue Counterpart to Monoclonal B-Cell Lymphocytosis Characterized
3D Imaging Method Determines Prostate Cancer Aggressiveness
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.