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Microbiology

Image: Unnecessary testing for urinary tract infections can be significantly reduced (Photo courtesy of Nicole Wetsman).

Unnecessary Testing for UTIs Significantly Reduced

Tests to detect urinary tract infections (UTI) often are performed routinely in hospitals, even when patients do not have symptoms. Such testing "just to be safe" can return results that lead doctors to prescribe antibiotics when there is little to no evidence to warrant such treatment. More...
04 Mar 2019
Image: The T8 Isothermal Diagnostics Instrument provides quantitative and qualitative results for molecular diagnostic isothermal assay applications (Photo courtesy of Axxin).

Buruli Ulcer Pathogen Detected by Isothermal RPA Assay

Buruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans. The pathogenesis of BU is linked to the production of a polyketide toxin known as mycolactone, which is cytotoxic and has immunomodulatory properties and presents as nodules, plaques, ulcers and edema. More...
28 Feb 2019
Image: A male and a female gametocyte of Plasmodium falciparum (Photo courtesy of Professor David Baker).

Saliva-based Test Detects Infectious Subclinical Malaria

Low-density subclinical infection with Plasmodium falciparum among defined population subsets has been shown to be an important but cryptic facet of malaria transmission. Typically, these individuals are not readily detected by currently available point-of-need (PON) rapid diagnostic tests (RDTs) or microscopy. More...
27 Feb 2019
Image: Dr. Krishnan Chittur, PhD, chief technology officer and co-founder of GeneCapture, holds the prototype of the rapid infection test cartridge (Photo courtesy of GeneCapture).

Assay Targets Antibiotic Resistance with Pathogen Identification

A rapid diagnostic device has been developed to detect and identify the source of an infection in less than one hour. More...
18 Feb 2019
Image: A diagram of the 20-Gene Set Predictive of Progression to Severe Dengue study (Photo courtesy of Stanford University School of Medicine).

Dengue Severity Predicted by Gene Expression Signature

About 400 million individuals annually are infected with any of the four dengue virus (DENV) serotypes and although the majority of symptomatic individuals present with acute dengue fever, a fraction, between ∼5% to 20% of these patients progress to severe dengue infection. More...
14 Feb 2019
Image: An Evalyn Brush used for patient self-sampling of the cervico-vaginal area (Photo courtesy of Rovers Medical Devices).

Accuracy of Self-Sampling for HPV Screening Evaluated

Molecular testing for human papillomavirus (HPV) using patient-collected cervico-vaginal samples has shown similar levels of accuracy to testing done on clinician-collected samples and could boost participation in overall HPV screening. More...
13 Feb 2019
Image: The Mastercycler X50 for polymerase chain reactions (Photo courtesy of Eppendorf).

Microbiome Helps Identify Patients with Early-Stage Cancer

Nearly 10,000 people are diagnosed with pancreatic cancer in the UK each year, with less than 1% surviving beyond ten years. More...
12 Feb 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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