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Hematology

Image: A peripheral blood film from a patient with sickle cell disease (Photo courtesy of Venngage).

New Method Rapidly Monitors Sickle Cell Disease

Sickle cell disease (SCD) is a hereditary disorder that affects red blood cells, distorting their natural disc shape into a crescent moon or "sickle" shape. Normal red blood cells move freely through small vessels throughout the body to deliver oxygen. With sickle cell disease, the misshapen red blood cells become hard and sticky, making it difficult for them to move through blood vessels. More...
26 Jun 2019
Chagas STAT-PAK assay is a rapid diagnostic test, easy to perform, requires no cold chain storage, uses a minimal sample size, and provides visual detection of antibodies to Trypanosoma cruzi (Photo courtesy of Chembio Diagnostic Systems).

Rapid Tests Assessed for Chronic Chagas Disease

 Chagas disease (CD) is a parasitic disease that can affect seriously the health status of affected individuals. People with CD, mainly living in remote areas of Latin America, often face major barriers to the disease recognition, diagnosis and treatment. In the U.S., there are estimated to be at least 300,000 cases of chronic Chagas disease among people originally from countries of Latin America where Chagas disease is endemic. More...
24 Jun 2019
Image: The XN-30 automated hematology analyzer that has an automatic measurement functions for red blood cells infected by malaria parasites (Photo courtesy of Sysmex).

Automated Hematology Analyzer Assessed for Malaria Diagnosis

Malaria remains a major cause of morbidity and mortality around the world. Sub-Saharan Africa is most affected with Plasmodium falciparum accounting for 99% of estimated cases. Timely and accurate diagnosis of malaria is essential for disease management and control. More...
11 Jun 2019
Image: Tendinous xanthomas on the hand of a patient with familial hypercholesterolemia (Photo courtesy of ScreenPro FH).

Blood Donations Screened for Familial Hypercholesterolemia

Familial hypercholesterolemia is an autosomal-dominant disorder that often causes premature coronary artery disease. Unfortunately, familial hypercholesterolemia remains largely undiagnosed. More...
06 Jun 2019
Image: The Nextera XT Index kit is used to prepare whole genome sequencing libraries for bacterial isolates (Photo courtesy of Dr. Thippeswamy Sannasiddappa).

Airway Microbiome Altered in Severe Asthma Linked to Neutrophils

Patients with mild-to-moderate asthma can experience difficulty breathing and it is especially difficult for those with Severe Asthma where symptoms can be life threatening. In either case, patients cannot participate in daily activities if their disease is uncontrolled. More...
06 Jun 2019
Image: A blood film showing typical red and white blood cells (Photo courtesy of Sherri Wick).

Neutrophil-Lymphocyte Ratio Proves Possible Biomarker for ED

Erectile dysfunction is described as the impotency to obtain or sustain an erection sufficiently in order to enable convincing sexual intercourse. Erectile dysfunction (ED) is estimated to affect about 75% of men over the age of 75 and 20% of men over the age of 20. More...
30 May 2019
Image: The BK virus (BKV) is a ubiquitous human polyomavirus that causes hemorrhagic cystitis in hematopoietic stem cell transplantation patients and nephropathy in kidney transplantation recipients. Poorly cohesive urothelial cells possess amorphous and smudgy nuclei, indicative of BK viral infection (Photo courtesy of Pathos223).

Stem Cell Transplantation Increases Risk of Infection-Related Mortality

Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapeutic modality for various malignant and nonmalignant hematological conditions. The best results of allogeneic HSCT were obtained when the stem cells from a human leukocyte antigen (HLA)-matched sibling were used, such a donor can only be found for approximately 30% of patients. More...
29 May 2019
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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