Hematology
Germline Genetic Testing Assesses Inherited Risk for Myeloid Malignancies
Inherited risk for hematologic malignancies was historically thought to be relatively rare; however, the increased use of next-generation sequencing has identified more patients with germline genetic mutations that are known to increase cancer risk. More...26 Dec 2019
Hepatic Dysfunction and Coagulopathy Quantified in Fatal Dengue Fever
Dengue fever (DF) is currently one of the most severe public health problems. Each year, an estimated 390 million dengue infections occur around the world. Clinical presentations of dengue are diverse and non-specific, often with unpredictable clinical progression and outcome. More...24 Dec 2019
Distinct Myelodysplastic Syndrome Subtypes Identified by Genomic, Transcriptomic Analysis
Myelodysplastic syndrome is a premalignant disease that affects myeloid cell. It is a precursor to acute myeloid leukemia, an aggressive blood cancer caused by the accumulation of immature blood cells. More...23 Dec 2019
Fresh Red Blood Cells Transfusions No Better Than Older Ones
Red blood-cell transfusions are commonly administered in critically ill children who have illnesses that increase the need for transfusion, such as trauma, cancer chemotherapy, major surgery with significant intraoperative bleeding, and conditions such as sickle cell disease and thalassemia. More...23 Dec 2019
Single-Cell Analysis Uncovers Regulatory Program in Rare Leukemia
Identifying the causes of human diseases requires deconvolution of abnormal molecular phenotypes spanning DNA accessibility, gene expression and protein abundance. Mixed-phenotype acute leukemia exhibits features of both acute myeloid leukemia and acute lymphoblastic leukemia and, as such, is marked by features of multiple hematopoietic lineages. More...18 Dec 2019
Autoimmunity Markers Prevalence Assessed in Immune Thrombocytopenia
Immune thrombocytopenia (ITP) is an acquired autoimmune disorder resulting from decreased platelet production and increased platelet destruction. Platelet autoantibodies in ITP lead to both acceleration of platelet destruction in the spleen and inhibition of platelet production by bone marrow megakaryocytes. More...17 Dec 2019
TP53 Gene Promoter Methylation Impacts Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is a clonal disorder that results in the accumulation of morphologically mature-looking and immunologically incompetent lymphoid cells in the bone marrow, peripheral blood, and lymphatic tissues. More...11 Dec 2019
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In Other News
Coagulation Function Explored for Gestational Diabetes Hemorrhage Risk
Hemophilia B Gene Increases Risk for Postpartum Bleeding
Acute Myeloid Leukemia Diagnosed by Convolutional Neural Networks
Next Generation Glycated Hemoglobin Assay Evaluated
Second Malignancy Risk Higher for Some Leukemia Survivors
Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants
Routine Blood Parameters Predict Invasive Aspergillosis Prognosis
Hematological Ratios Associated with Mortality in Pediatric Trauma Patients
Reference Intervals Established for Serum Ferritin in Chinese Adults
Measurable Residual Disease Assessed Post-Transplantation in Acute Lymphoblastic Leukemia
Allogeneic Transplantation Outcomes Compared in Sickle Cell Disease Patients
Biomarkers Analyzed for Central Nervous System Lymphoma
Specific Cytokines Are Significant Biomarkers for AML
Blood Monocyte Functions Altered in Parkinson's Disease
Two Different Mutations Identified as Cause of AML
Parkinson’s Gene Mutation Linked to Higher Risk of Leukemia
Human CRP-Levels Compared Using Point-of-Care Methods
Hematological Parameters Detect Patients with Acute VTE
Laser Incubator Developed for Rapid Blood Group Typing
Biomarker in Adolescence Linked to Early Mortality
Next-Gen Sequencing Matches Blood Group Antigens for Transfusion
Chronic Lymphocytic Leukemia Linked with Higher Melanoma Risk
Serum HMGB1 Levels Reflect Clinical Features of HLH
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.