Molecular Diagnostics

Biomarker Discovered for Hypervirulent Pathogen
There is no accurate method for distinguishing between the hypervirulent strain from the classical strain of Klebsiella pneumoniae (cKp), which is most often seen in the Western hemisphere, and is less virulent and usually causes infections in hospital settings. More...18 Jul 2018

MicroRNA Pair Serves as Biomarkers for Rapid Sepsis Diagnosis
Two microRNAs that could be the basis of a test to help physicians classify patients into those with organ failure who are at high risk of sepsis and death and those patients with milder infections have been identified. More...16 Jul 2018

Optimization of Analytical Procedures Reduces Variability of Results
A team of Spanish researchers recently described the development and optimization of several "quantitative suspension array" assays (qSAT) designed to assess natural and vaccine-induced responses to malaria and other parasites. More...16 Jul 2018

Genetic Connections Uncovered Between Psychiatric Disorders
Brain disorders may exhibit shared symptoms and substantial epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed study of phenotypes with different ages of onset, severity, and presentation poses a considerable challenge. More...12 Jul 2018

Female Bladder Bacteria Reveal Urogenital Microbiota
Contrary to medical dogma, urine is not sterile, even in asymptomatic individuals. For over 60 years, the standard urine culture protocol has represented the primary tool for detecting bacteria in clinical microbiology laboratories. More...11 Jul 2018

Lipid Species Offer Insights into Metabolic Health
Heart disease is the number one killer in the USA, and high triglyceride levels in the blood are cited as just one of several risk factors. Millions of lipid panels, blood tests that look at cholesterol levels as well as triglycerides, are performed in clinics each year. More...11 Jul 2018

In Other News
Simple Test Could Reduce Treatment of Bladder Cancer
Current-Tunneling Measurements Analyze Single DNA Molecules
Variant CJD Diagnosed by Protein Misfolding Amplification
Recurrent Rearrangements Identified in Soft Tissue Tumors
DNA Code Unraveled for Rare Neurologic Disease
Measurement of Two Biomarkers Predicts Diabetes Risk
UTIs Diagnosed with Genetic Analysis of Cell-Free DNA
Gene Signatures and Biomarkers Predict RA Onset
Extracellular RNA Helps Diagnose Medical Conditions
Genomic Atlas of Human Plasma Proteome Publicized
Metagenomics Uncover Pathogens and Drug-Resistance Genes
Biomarker Panel Distinguishes TB from Other Infections
RNA Sequencing of Nasal Samples Used to Diagnose Asthma
ELISA-Based Neonatal Screening Line Offers Menu of Eight Kits
High Vitamin D Levels Linked to Lower Cholesterol
MSI Tumor Analysis Implicates Lynch Syndrome in Cancer Types
Molecular Test Developed for Nasopharyngeal Carcinoma
RT-PCR Assay Developed to Detect Bloodstream Infections
Assay Detects CP Risk in Premature Babies
Leprosy Neural Impairment Diagnosis Evaluated by Tests
Link Found Between Alcohol, Genes and Heart Failure
Chromosome Study Leads to Counseling Pregnant Women
Mutations Missed in Congenital Disease Screening
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