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Medica 2025
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Molecular Diagnostics

Image: A histopathology of cytomegalovirus infection in the lung showing typical owl-eye inclusions; FDA clears new CMV test for newborns (Photo courtesy of Danny Wiedbrauk, PhD).

Newborn Cytomegalovirus Test Cleared for Marketing

Cytomegalovirus or CMV is a common virus that infects people of all ages. In the USA, nearly one in three children are already infected with CMV by age five and over half of adults by age 40 have been infected with CMV. More...
20 Dec 2018
Image: Tumor heterogeneity, clonal evolution and therapy resistance was revealed using single cell profiling of multiple myeloma patients (Photo courtesy of Weizmann Institute of Science).

Unique Genetic Makeup of Myeloma Tumor Cells Profiled

Multiple myeloma is the second-most common type of blood cancer. Multiple myeloma occurs when plasma cells in the bone marrow, the cells that produce antibodies, proliferate out of control and lead to various type of organ failure and death. More...
17 Dec 2018
Image: The Rapid Amplification of ctDNA Ends (RACE) next-generation sequencing (NGS) assay (Photo courtesy of ArcherDx).

Liquid Biopsy Identifies Advanced Lung Cancer Drivers

Liquid biopsy for plasma circulating tumor DNA (ctDNA) next-generation sequencing (NGS) is commercially available and increasingly adopted in clinical practice despite a paucity of prospective data to support its use. More...
13 Dec 2018
Image: The HiSeq 4000 Systems leverage innovative patterned flow cell technology to provide rapid, high-performance sequencing. Perform production-scale, high-throughput exome or transcriptome sequencing projects quickly and economically (Photo courtesy of Illumina).

Metagenomic Sequencing Proposed for Respiratory Tract Infection Detection

Lower respiratory tract infections (LRTIs) are the leading cause of infectious disease-related deaths worldwide yet remains challenging to diagnose because of limitations in existing microbiologic tests. More...
13 Dec 2018
Image: The CareStart HRP2 rapid diagnostic test for Plasmodium falciparum malaria (Photo courtesy of Access Bio).

Plasmodium vivax Isolated in Duffy Negative Individuals

Malaria in Nigeria is principally due to Plasmodium falciparum and, to a lesser extent to P. malariae and P. ovale. P. vivax is thought to be absent in Nigeria in particular and sub-Saharan Africa in general, due to the near fixation of the Duffy negative gene in this population. More...
12 Dec 2018
Image: The UltrafleXtreme MALDI-TOF/TOF mass spectrometer (Photo courtesy of Bruker Daltonics).

MALDI-TOF MS Identifies Oomycete Causing Pythiosis

Pythiosis is an invasive, difficult-to-treat, life-threatening infectious disease caused by Pythium insidiosum, a member of the unique group of fungus-like microorganisms called oomycetes. The disease has been increasingly reported worldwide. More...
12 Dec 2018
Image: A malignant melanoma of the skin (Photo courtesy of Juan Gaertner).

Circulating Tumor DNA Detects Early Melanoma Growth

According to the National Cancer Institute, there were 91,270 new cases of melanoma in 2018, making up more than 5% of all new cancer cases. There were 9,320 estimated deaths in 2018, and 91.8% of patients survive five years or longer. More...
11 Dec 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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