Molecular Diagnostics
Fusion Genes Diagnosis Uses Targeted RNA Sequencing
Chromosomal rearrangements that juxtapose two different genes together can form a fusion gene. Fusion genes play a causal role in tumorigenesis, accounting for ~20% of human cancer morbidity. However, the prevalence of fusion genes varies widely across different cancers, and many fusion genes are specific to certain cancer sub-types. More...10 Apr 2019
Liquid Biopsy Potential Tested with ddPCR Technology
Droplet digital polymerase chain reaction (ddPCR) technology has been used to investigate the benefits of tracking drug-resistance mutations in the circulating DNA (ctDNA) of patients with hormone receptor-positive (HR+) metastatic breast cancer. More...10 Apr 2019
Genomic Analysis Used to Diagnose Neurodevelopmental and Congenital Anomalies
A recent paper described the use of genomic DNA methylation analysis to facilitate the molecular diagnosis of unresolved clinical cases of neurodevelopmental and congenital anomalies (ND/CAs) and highlighted the potential value of epigenomic testing in the routine clinical assessment of these disorders. More...08 Apr 2019
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Clinical ddPCR Diagnostic Test System Gets FDA Clearance
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.