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Recent News Expo Medica 2025 Clinical Chem. Molecular Diagnostics Hematology Immunology Microbiology Pathology Technology Industry Focus

Molecular Diagnostics

Image: Histopathology of a typical neuroblastoma with rosette formation (Photo courtesy of Dr. Mark Applebaum, MD).

Neuroblastoma Molecular Analysis Leads to Prognostic Markers

Neuroblastoma is a pediatric tumor of the sympathetic nervous system. Its clinical course ranges from spontaneous tumor regression to fatal progression. It most frequently starts from one of the adrenal glands, but can also develop in the neck, chest, abdomen, or spine. More...
27 Dec 2018
Image: SureSelect Target Enrichment Systems (Photo courtesy of Agilent Technologies).

Genetic and Epigenetic Features Found in Glioma Tumors

Neurofibromatosis type 1 (NF1) is a multisystem genetic disorder that is characterized by cutaneous findings, most notably café-au-lait spots and axillary freckling, by skeletal dysplasias, and by the growth of both benign and malignant nervous system tumors, most notably benign neurofibromas. More...
27 Dec 2018
Image: Photomicrograph of a buffy coat smear of the patient’s blood collected on the third hospital day. Anaplasma phagocytophilum inclusions are seen in the cytoplasm of two different granulocyte stages (a metamyelocyte and a myelocyte). Arrows indicate morulae (Photo courtesy of Westchester Medical Center).

Tick-Borne Diseases Diagnosed with Multiplex Molecular Panel

Tick-borne diseases, which afflict humans and other animals, are caused by infectious agents transmitted by tick bites. Tick-borne illnesses are caused by infection with a variety of pathogens, including rickettsia and other types of bacteria, viruses, and protozoa. More...
26 Dec 2018
Image: A simplified diagram of the Hepatitis C (HCV) replication cycle (Photo courtesy of Graham Malcolm Beards, DSc).

HCV-RNA Present in Body Fluids in High Viral Load Patients

Hepatitis C virus (HCV) causes both acute and chronic infection. Acute HCV infection is usually asymptomatic, and is only very rarely (if ever) associated with life-threatening disease. About 15%–45% of infected persons spontaneously clear the virus within six months of infection without any treatment. More...
26 Dec 2018
Image: Visual detection of RT-LAMP assay. The tubes represent BAV strains and the negative controls used in the visual inspection. 1-7, BAV strains; 8-13, other viruses; 14, negative control (Photo courtesy of Wuhan Institute of Virology).

Banna Virus Detected by Reverse Transcription-Loop-Mediated Isothermal Amplification

Banna virus (BAV) has been isolated from a diverse group of vertebrates and invertebrates, including mosquitos, ticks, midges, cattle, and pigs from different regions in China, Vietnam, and Indonesia. BAV is considered to be an emerging pathogen that can result in human infections with possible manifestation of fever and viral encephalitis. More...
25 Dec 2018
Image: The Infinium Omni2.5-8 BeadChip offers an optimal and comprehensive set of both common and rare single nucleotide polymorphism (SNP) content (Photo courtesy of Illumina).

Alzheimer's Disease Risk Alleles Profiled in Latino Populations

The apolipoprotein E (APOE) gene encodes three common isoforms known as ε2, ε3, and ε4. These are determined by two single nucleotide polymorphisms (SNPs) that result in amino acid substitutions and associated functional changes in the protein. More...
24 Dec 2018
Image: Bone marrow aspirate smear from a patient with acute lymphoblastic leukemia reveals increased blasts which are small to medium in size with high nuclear-to-cytoplasmic ratios, round to irregular nuclei, smooth chromatin, and scant basophilic agranular cytoplasm (Photo courtesy of Karen M. Chisholm MD, PhD).

Genetic Marker Predicts Early Relapse in Pediatric ALL

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer; however, treatment has improved dramatically due to the ability to stratify patients into groups based on risk factors and genetic analysis. More...
24 Dec 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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