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Molecular Diagnostics

Image: A simplified diagram of the Hepatitis C (HCV) replication cycle (Photo courtesy of Graham Malcolm Beards, DSc).

HCV-RNA Present in Body Fluids in High Viral Load Patients

Hepatitis C virus (HCV) causes both acute and chronic infection. Acute HCV infection is usually asymptomatic, and is only very rarely (if ever) associated with life-threatening disease. About 15%–45% of infected persons spontaneously clear the virus within six months of infection without any treatment. More...
26 Dec 2018
Image: Visual detection of RT-LAMP assay. The tubes represent BAV strains and the negative controls used in the visual inspection. 1-7, BAV strains; 8-13, other viruses; 14, negative control (Photo courtesy of Wuhan Institute of Virology).

Banna Virus Detected by Reverse Transcription-Loop-Mediated Isothermal Amplification

Banna virus (BAV) has been isolated from a diverse group of vertebrates and invertebrates, including mosquitos, ticks, midges, cattle, and pigs from different regions in China, Vietnam, and Indonesia. BAV is considered to be an emerging pathogen that can result in human infections with possible manifestation of fever and viral encephalitis. More...
25 Dec 2018
Image: The Infinium Omni2.5-8 BeadChip offers an optimal and comprehensive set of both common and rare single nucleotide polymorphism (SNP) content (Photo courtesy of Illumina).

Alzheimer's Disease Risk Alleles Profiled in Latino Populations

The apolipoprotein E (APOE) gene encodes three common isoforms known as ε2, ε3, and ε4. These are determined by two single nucleotide polymorphisms (SNPs) that result in amino acid substitutions and associated functional changes in the protein. More...
24 Dec 2018
Image: Bone marrow aspirate smear from a patient with acute lymphoblastic leukemia reveals increased blasts which are small to medium in size with high nuclear-to-cytoplasmic ratios, round to irregular nuclei, smooth chromatin, and scant basophilic agranular cytoplasm (Photo courtesy of Karen M. Chisholm MD, PhD).

Genetic Marker Predicts Early Relapse in Pediatric ALL

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer; however, treatment has improved dramatically due to the ability to stratify patients into groups based on risk factors and genetic analysis. More...
24 Dec 2018
Image: The HiSeq 2500 System is a powerful high-throughput sequencing system (Photo courtesy of Illumina).

Colorectal Cancer Risk Linked to Common and Rare Variants

Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Screening, by one of a number of methods, is recommended starting from the age of 50 to 75. More...
20 Dec 2018
Image: A histopathology of cytomegalovirus infection in the lung showing typical owl-eye inclusions; FDA clears new CMV test for newborns (Photo courtesy of Danny Wiedbrauk, PhD).

Newborn Cytomegalovirus Test Cleared for Marketing

Cytomegalovirus or CMV is a common virus that infects people of all ages. In the USA, nearly one in three children are already infected with CMV by age five and over half of adults by age 40 have been infected with CMV. More...
20 Dec 2018
Image: Tumor heterogeneity, clonal evolution and therapy resistance was revealed using single cell profiling of multiple myeloma patients (Photo courtesy of Weizmann Institute of Science).

Unique Genetic Makeup of Myeloma Tumor Cells Profiled

Multiple myeloma is the second-most common type of blood cancer. Multiple myeloma occurs when plasma cells in the bone marrow, the cells that produce antibodies, proliferate out of control and lead to various type of organ failure and death. More...
17 Dec 2018
New
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DH-800 Series
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Immunochromatographic Assay
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OptoMonitor


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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