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Molecular Diagnostics

Image: A micrograph of prostate adenocarcinoma, acinar type, the most common type of prostate cancer (Photo courtesy of Wikimedia Commons).

Elevated Gene Expression Correlates with Prostate Cancer Severity

Elevated expression of the gene ANO7 has been shown to correlate with the severity and possible outcome of prostate cancer (PrCa). More...
10 Sep 2018
Image: Whole-exome sequencing provides an underlying diagnosis in an efficient, cost-effective manner and incorporates analysis of newly characterized genes (Photo courtesy of Ambry Genetics).

Breast and Ovarian Cancers Associated with Predisposition Genes

Since the discovery of BRCA1 and BRCA2, multiple high- and moderate-penetrance genes have been reported as risk factors for hereditary breast cancer, ovarian cancer, or both. More...
06 Sep 2018
Image: The HiSeq 4000 Systems provide a multi-application solution for production-scale genomic laboratories (Photo courtesy of Illumina).

Unexplained Illness Puts Pathogen Discovery to Test

High-throughput sequencing can provide insights into epidemiology and medicine through comprehensive surveys of viral genetic sequences in environmental and clinical samples. More...
05 Sep 2018
Image: Bone marrow aspirate from a patient with diffuse large B cell lymphoma (Photo courtesy of Peter Maslak).

Blood Test Predicts Lymphoma Therapy Success

A blood test can predict which patients with a type of cancer called diffuse large B cell lymphoma are likely to respond positively to initial therapy and which are likely to need more aggressive treatment. More...
04 Sep 2018
Image: Diagram of the Seq-Well low-cost platform for single-cell RNA sequencing (Photo courtesy of Shalek Lab).

Analysis of Nasal Polyps Suggests Mechanisms of Inflammation

Allergic inflammation can develop from persistent activation of type 2 immunity in the upper airway, resulting in chronic rhinosinusitis, which ranges in severity from rhinitis to severe nasal polyps. More...
04 Sep 2018
Image: A micrograph showing granulomatous inflammation of bladder neck tissue due to Bacillus Calmette-Guérin (BCG) used to treat bladder cancer (Photo courtesy of Wikimedia Commons).

New Test Predicts Potential Success of BCG Immunotherapy for Bladder Cancer

A laboratory test that measures the amount of IL2 secretion from CD4+ T cells after overnight in vitro incubation with tuberculin predicts the potential success of BCG (Bacille Calmette-Guérin) immunotherapy treatment for bladder cancer. More...
03 Sep 2018
Image: An illustration depicting a deep vein thrombosis (Photo courtesy of Wikimedia Commons).

Rapid Method Suggested for Diagnosis of DVT

A simple blood test has been proposed as an alternative to the fairly costly and time intensive ultrasound procedure for diagnosis of deep vein thrombosis (DVT). More...
03 Sep 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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