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Molecular Diagnostics

Image: A micrograph of a colonic biopsy showing inflammation of the large bowel in a case of inflammatory bowel disease (Photo courtesy of Wikimedia Commons).

Metabolomics Analysis Method Used for Diagnosis of IBD

A team of Canadian researchers used an advanced metabolomics approach to differentiate inflammatory bowel syndrome (IBS) from other related gastrointestinal disorders. More...
15 Jul 2019
Image: A diagram of how the X-Linked DDX3X RNA helicase dictates translation reprogramming and metastasis in melanoma (Photo courtesy of Lund University).

Protein Linked to Aggressive Skin Cancer

Almost 300,000 people worldwide develop malignant melanoma each year. The disease is the most serious form of skin cancer and the number of cases reported annually is increasing, making skin cancer one of Sweden's most common forms of cancer. More...
10 Jul 2019
Image: A histological preparation from a patient with invasive lobular carcinoma, demonstrating a predominantly lobular growth pattern (Photo courtesy of KGH).

Test Determines If Cancer Patients Require Chemotherapy

Invasive lobular carcinoma (ILC) is the most common special type of breast cancer, and is characterized by functional loss of E-cadherin, resulting in cellular adhesion defects. ILC typically present as estrogen receptor positive, grade 2 breast cancers, with a good short-term prognosis. More...
09 Jul 2019
Image: The cobas e 601 module for immunoassay tests (Photo courtesy of Roche Diagnostics).

Automated Approach Predicts Alzheimer's Disease Risk

An automated immunodiagnostic test predicts risk of developing Alzheimer's disease by measuring the level of beta-amyloid (Abeta) in the blood, which accurately reflects the accumulation of this protein in the brain. More...
08 Jul 2019
Image: A micrograph of the superficial cerebral cortex showing neuron loss and reactive astrocytes in a person that has had a stroke (Photo courtesy of Wikimedia Commons).

Levels of NfL Increase Accuracy of Stroke Risk Prediction

Serum levels of neurofilament light polypeptide have been found to predict the likelihood of suffering a stroke and to add considerably to the discriminatory power of the Framingham Stroke Risk Score in a group of middle-aged and older adults with diabetes mellitus. More...
08 Jul 2019
Image: The RealStar Zika Virus reverse transcription polymerase chain reaction (RT-PCR) (Photo courtesy of Altona Diagnostics).

Whole-Blood Testing Diagnoses Acute Zika Virus Infections

Zika virus infections are linked to congenital malformations in neonates from mothers infected during pregnancy and to neurologic disorders in adults. Reverse transcription polymerase chain reaction (RT-PCR) is the most reliable method for confirming Zika virus infections. More...
04 Jul 2019
Image: A histopathology of lymph node with metastatic adenocarcinoma of the colon (Photo courtesy of Dr. Ed Uthman M.D).

Metastases May Form Early in Development of Colorectal Cancer

Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and feeling tired all the time. More...
04 Jul 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.