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Medica 2025
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Molecular Diagnostics

Image: Kidney specimen from patient who died with acute kidney injury. Image shows marked pallor of the cortex, contrasting to the darker areas of surviving medullary tissue (Photo courtesy of Wikimedia Commons)

Proteinuria After Acute Kidney Injury Predicts Development of Progressive Disease

 A report has suggested that testing recently hospitalized kidney patients for proteinuria could be a way to identify those at higher risk for developing progressive kidney disease, which could require dialysis or surgery. More...
03 Feb 2020
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Large Number of Genes Linked to Risk of Developing Autism Spectrum Disorder

 A large exome sequencing study of autism spectrum disorder identified 102 genes associated with risk for autism. More...
03 Feb 2020
Image: Dark field microscopy of a culture of blood in EMJH semisolid media showing spirochetes with morphology compatible with Leptospira (Photo courtesy of Alejandro Llanes).

Multivariable Diagnostic Prediction Score Validated for Leptospirosis

 Leptospirosis is a bacterial disease that affects humans and animals. It is caused by bacteria of the genus Leptospira. In humans, it can cause a wide range of symptoms, some of which may be mistaken for other diseases. More...
30 Jan 2020
Image: The DS-11 Series of Spectrophotometers are used to perform fast quantification of nucleic acids and proteins (Photo courtesy of DeNovix).

Homologous Recombination Defects Prevalent in African-American Cancer Patients

 In the USA, African-Americans have the highest cancer incidence and lowest survival across multiple cancer types. The reasons for these persistent trends are not clear. More...
28 Jan 2020
Image: Ball-and-stick model of the fentanyl molecule in the crystal structure of fentanyl citrate-toluene solvate (Photo courtesy of Wikimedia Commons)

Siemens Healthineers Introduces Autoanalyzer Assay for Monitoring Fentanyl Usage

 A recently introduced diagnostic test for use on clinical chemistry autoanalyzers measures the levels of the opioid drug fentanyl and its primary metabolite norfentanyl. More...
28 Jan 2020
Image: Optic nerve in advanced glaucoma disease (Photo courtesy of Wikimedia Commons)

Genetic Risk Score Detects Glaucoma and Predicts Progression of the Disease

 Establishment of a glaucoma polygenic risk score (PRS) will facilitate the development of a personalized approach for earlier treatment of high-risk individuals, with less intensive monitoring and treatment being possible for lower-risk groups. More...
28 Jan 2020
Image: Acute Myeloid Leukemia: The blasts are medium to large in size and have an elevated nuclear: cytoplasmic ratio. The nuclear chromatin is fine and there are prominent nucleoli. Frequent blasts show indented or “cup-shaped” nuclear contours (Photo courtesy of Elizabeth Courville, MD).

Bone Marrow Donors May Transfer Pathogenic Mutations to Patients

 Clonal hematopoiesis of indeterminate potential, or CHIP, is characterized by the presence of mutant hematopoietic stem cell clones in the bone marrow without overt signs of disease. More...
27 Jan 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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