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Molecular Diagnostics

Image: Culture showing the typical brown diffusable pigment in the agar (inset) and phialides of Madurella mycetomatis (Photo courtesy of University of Adelaide).

Real-Time PCR Developed for Eumycetoma Diagnosis

 Mycetoma, a progressive and disfiguring disease, is one of the neglected tropical diseases, caused by both bacteria and fungi. Eumycetoma is the fungal type and mainly caused by species of the genus Madurella. More...
06 Feb 2020
Image: A melanoma on a patient`s skin: a new test predicts which melanoma patients are at risk of cancer recurrence and metastases (Photo courtesy of US National Cancer Institute).

Technique Predicts Cancer Recurrence Risk for Melanoma Patients

 Many primary melanomas can be cured by having this lesion removed, but melanoma can also recur and spread; an analysis of the removed lesion can offer some information on the likelihood that the cancer will recur. More...
05 Feb 2020
Image: The innuPREP MP Basic Kit A for fast, efficient isolation of DNA and RNA of either viral or bacterial origin (Photo courtesy of Analytik Jena).

Loop-Mediated Isothermal Amplification Discriminates Yaws Bacterium

 Yaws, a neglected tropical disease caused by the bacterium Treponema pallidum subspecies pertenue, predominantly affects children living in low-income, rural communities of warm and humid regions. More...
05 Feb 2020
Image: Histopathology of kidney disease: showing completely sclerotic glomeruli and severe chronic tubulointerstitial nephritis (Photo courtesy of Jian-Hua Qiao, MD, FCAP).

Urinary Metabolite GWAS Leads to Biomarkers of Kidney Disease

 The kidneys integrate information from continuous systemic processes related to the absorption, distribution, metabolism and excretion (ADME) of metabolites. Scientists have identified ties between urine metabolite levels and common genetic variants, laying the foundation for a more refined view of human metabolic processes and the tissues in which they take place. More...
04 Feb 2020
Illustration

Blood Test Measuring anti-Müllerian Hormone Predicts Time to a Woman’s Final Menstrual Period

 A blood test has been developed that helps predict the time to a woman’s final menstrual period (FMP). More...
04 Feb 2020
Image: Photomicrograph of cancer cells (Photo courtesy of Baylor College of Medicine)

A Needle Biopsy-based Proteogenomics Approach for Cancer Diagnosis

 A recent report described a proteogenomics approach for cancer diagnosis, which used tissue-sparing needle biopsy specimen processing and micro-scaled analytical proteomics techniques. More...
04 Feb 2020
Image: Kidney specimen from patient who died with acute kidney injury. Image shows marked pallor of the cortex, contrasting to the darker areas of surviving medullary tissue (Photo courtesy of Wikimedia Commons)

Proteinuria After Acute Kidney Injury Predicts Development of Progressive Disease

 A report has suggested that testing recently hospitalized kidney patients for proteinuria could be a way to identify those at higher risk for developing progressive kidney disease, which could require dialysis or surgery. More...
03 Feb 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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