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Molecular Diagnostics

Image: Histopathology of Lung adenocarcinoma (Photo courtesy of Nikon).

Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans

 Lung adenocarcinoma is a subtype of non-small cell lung cancer (NSCLC). Lung adenocarcinoma is categorized as such by how the cancer cells look under a microscope. Lung adenocarcinoma starts in glandular cells, which secrete substances such as mucus, and tends to develop in smaller airways, such as alveoli. More...
18 Feb 2020
Image: The photo shows a portable lab that plugs into a smartphone to diagnose diseases like malaria or coronavirus (Photo courtesy of Joseph Fuqua II, University of Cincinnati Creative Services)

Autonomous Microchannel Analyzer Combines with Smartphone for Off-Site Disease Diagnostics

 A novel microchannel capillary flow assay platform for detection of pathogenic microorganisms or other antigens combines with a smartphone for display, data transfer, storage, and analysis. More...
18 Feb 2020
Image: Solution structure of IL-18 (interleukin 18) protein (Photo courtesy of Wikimedia Commons)

Protein Panel Predicts Risk for Development of Cerebral Small Vessel Disease

 A network of six inflammatory biomarkers centered on interleukin-18 (IL-18) is able to predict risk for development of cerebral small vessel disease (CSVD), a brain disease currently diagnosed by MRI (magnetic resonance imaging) scan. More...
17 Feb 2020
Image: Histopathology of early gastric cancer, an intramucosal adenocarcinoma. A blood test used in a targeted methylation (TM) sequencing assay may help detect hard-to-detect gastrointestinal cancers in asymptomatic individuals (Photo courtesy of Andrey Bychkov, MD, PhD).

Blood Test Lead to Earlier Detection of Gastrointestinal Cancers

 Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract (GI tract) and accessory organs of digestion, including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum and anus. More...
13 Feb 2020
Image: The FUJI DRI-CHEM IMMUNO AG1 analyzer (Photo courtesy of FUJI FILM).

Rapid Antigenic Diagnostic Test Validated for Ebola Virus Disease

 Hemorrhagic fever outbreaks are difficult to diagnose and control in part because of a lack of low-cost and easily accessible diagnostic structures in countries where etiologic agents are present. Initial clinical symptoms are common and shared with other endemic diseases such as malaria or typhoid fever. More...
13 Feb 2020
Image: Structure of the lipocalin 2 (LCN2) protein (Photo courtesy of Wikimedia Commons)

Lipocalin 2 Identified as Biomarker for Differential Diagnosis of Vascular Dementia

 Results obtained by a study conducted by several European research institutes suggest that lipocalin 2 is a promising biomarker for the differential diagnosis of vascular dementia. More...
12 Feb 2020
Image: Illustration of a 2019- novel coronavirus (nCoV) virion (Photo courtesy of Alissa Eckert, MS/CDC).

CDC Provides Test Protocol for Novel Coronavirus

 The US Centers for Disease Control and Prevention (Atlanta GA, USA) has publicly posted its assay for novel coronavirus 2019-nCoV and is now developing the test into kits. The CDC diagnostic test is a reverse transcriptase real-time PCR (rRT-PCR) assay developed for respiratory and blood serum samples. The protocol to make the assay has been made publicly available. More...
11 Feb 2020
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