Molecular Diagnostics
Extrachromosomal Circular DNA Drives Oncogenic Genome Remodeling in Neuroblastoma
Circularized DNA falling outside of linear chromosomes may serve as a recurrent source of somatic rearrangements in neuroblastoma, a pediatric cancer affecting immature cells in the sympathetic nervous system. More...02 Jan 2020
Liquid Biopsy Detects Breast Cancer Residual Disease
The concept of circulating DNA or tumor cells to identify patients with residual cancer present after early-stage, putatively curative treatment has made rapid strides across multiple tumor types since some of the first promising tests in colorectal cancer. More...02 Jan 2020
Standard Pathology Tests Outperform Molecular Subtyping in Bladder Cancer
Evolving diagnostic approaches include compiling databanks on gene expression and mutations present in a cancer type to find patterns of gene expression that are then used to subtype tumors that "pathologically look similar" but are molecularly different. More...02 Jan 2020
Memory Loss in Alzheimer’s Disease Linked to Both Amyloid Plaques and Tau Tangles
A team of neurodegenerative disease researchers has linked the APOE-epsilon-4 gene to increased formation of toxic tau protein aggregates (tangles) as well as amyloid-beta plaques in individuals with Alzheimer’s disease (AD). More...31 Dec 2019
Elevated Levels of Lipoprotein(a) Increase Cardiovascular Disease Risk in Patients with Type I Diabetes
Results obtained by a team of Swedish researchers indicated that individuals with type I diabetes were at greater risk of developing cardiovascular disease (CVD) if they had elevated levels of lipoprotein(a) in their blood. More...30 Dec 2019
Novel Liquid Biopsy Method for Detection of Cancer MicroRNA Biomarkers
The potential usefulness of the “liquid biopsy” approach for detection of cancer biomarkers in the blood has been increased by the development of a method for capturing and counting cancer-associated microRNAs. More...30 Dec 2019
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Novel Biomarker Predicts Dementia Risk
Genetic Biomarkers Associated with Autism Spectrum Disorders Identified
Implement Diagnostics System Improves Infectious Disease Testing
Mutations Causing Loss of Tumor Suppressor Gene Increase Aggressiveness of Rare Bile Duct Cancer
Childhood Kidney Cancer Arises from Altered Normal Tissue
Predicting Age by Profiling Circulating Plasma Proteins
A Rapid Method for Selecting the Proper Antibiotic to Treat Multidrug Resistant Bacteria
Chronic Comorbidities Are Prevalent Among People with Chagas Disease
A One-step Rapid Point-of-Care Assay for Diagnosis of Celiac Disease
Diagnosis and Monitoring of Patients with Hepatitis C Virus
TP53 Gene Promoter Methylation Impacts Chronic Lymphocytic Leukemia
Three Factors Distinguish MODY, a Rare Diabetes, in Youth
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.