Molecular Diagnostics
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
The overall low survival rate of patients with lung cancer calls for improved detection tools to enable better treatment options and improved patient outcomes. Lung cancer affects about 228,000 people a year in the USA and has a five-year survival rate just shy of 20%. More...16 Mar 2020
Methylated DNA in Saliva Samples Predicts Likelihood of Developing Childhood Obesity
A study based on analysis of saliva samples supports the concept that determination of DNA methylation in salivary tissue can be used to predict the eventual development of obesity by Hispanic children. More...16 Mar 2020
Noninvasive Urine Test Developed for Prostate Cancer
It is estimated that 191,930 men will be diagnosed with prostate cancer (PCa) in USA this year, and 33,330 of these patients will die of the disease this year. PCa is one of the second most frequently diagnosed cancer deaths among men worldwide. More...12 Mar 2020
Presenilin1 Gene Characteristics Used as Alzheimer's Disease Biomarker
Alzheimer's Disease manifests as a familial disease with monogenic inheritance and early onset (Early Onset AD: EOAD), or as a sporadic, multifactorial, late-onset disease (Late Onset AD: LOAD). The latter accounts for more than 90% of all cases and its causes are unknown. More...11 Mar 2020
Blood Test Predicts Response to Immunotherapy in Metastatic NSCLC
Non-small cell lung cancer (NSCLC) patients with higher measures of tumor mutations that show up in a blood test generally have a better clinical response to PD-1-based immunotherapy treatments than patients with a lower measure of mutations. More...10 Mar 2020
Circulating Levels of Phosphorylated Tau Protein Differentiate Alzheimer’s Disease from other Types of Dementia
Elevated levels of circulating phosphorylated tau 181 (pTau181) protein correlate with Alzheimer's disease (AD) and distinguish it from frontotemporal dementia, a condition that is often misdiagnosed as AD. More...10 Mar 2020
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In Other News
High-Throughput Isothermal HPV Test Validated
Novel 3-Gene Transcriptional Signature Stratified for Tuberculosis Contacts
Increased Levels of Serum Amyloid-beta Linked to Development of Cardiovascular Disease
Monogenic Hypercholesterolemia Increases Cardiovascular Disease Risk
Leukemic Stem Cell Score Predicts Myelodysplastic Syndrome Prognosis
Identification of a MicroRNA Biomarker Linked to a Childhood Liver Disease
Heterogeneous Populations of Melanoma Circulating Tumor Cells Detected
Researchers Identify Genes Linked to the Development of Monogenic Diabetes
Fetal Cell-Based NIPT Demonstrated by Droplet Digital PCR
Point-Of-Care Molecular Tests Compared for Pediatric Influenza
Genetic Risk Factors Found in Gestational Diabetes
Combining IL-6 Measurement with a Standard Biomarker Panel Improves Diagnosis of Ovarian Cancer
Novel Blood Tests Predict Progression of Parkinson's Disease
Elevated Levels of Certain Immunoproteosome Components Predict Potential Success of Checkpoint Inhibitor Therapy in Melanoma Patients
Proteogenomic Characterization of Endometrial Carcinoma Analyzed
Uric Acid in Saliva Is a Biomarker for Body Fat Accumulation in Adolescents
Ratio of Serum Very-long-chain to Long-chain Ceramides Is Predictive of Dementia Risk
Factor IX Inhibitor Incidence in Pediatric Hemophilia B Examined
Several Genes Linked to Long QT Syndrome Reappraised
Modular Targeted Capture Assay Detects Clinically Significant Oncology Alterations
Assessment of Circulating Tumor Cells Identifyies Stage III Melanoma Patients at Risk for Relapse
Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans
Autonomous Microchannel Analyzer Combines with Smartphone for Off-Site Disease Diagnostics
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.