Molecular Diagnostics

A Non-Invasive Urine Test for Prediction of Kidney Transplant Failure
A non-invasive test that predicts potential kidney transplant failure combines the CRISPR gene editing tool with a lateral-flow visual readout procedure to analyse urine samples from transplantation recipients. More...21 Apr 2020

Real-Time Assay Evaluated for Two Sexually Transmitted Diseases
Chlamydia trachomatis and Neisseria gonorrhoeae are the two most commonly reported sexually transmitted infections (STIs) in the USA and the numbers of cases are increasing. C. trachomatis and N. gonorrhoeae infections in the rectum and pharynx are important extragenital reservoirs of infection. More...21 Apr 2020
RT-LAMP Assay Developed for SARS-CoV-2
SARS-CoV-2 is the causative viral pathogen of COVID-19, and diagnosis of COVID-19 can be done through CT scan of suspicious patients and a confirmatory laboratory test is performed using published real-time quantitative polymerase chain reaction (RT-qPCR) methods. More...20 Apr 2020

Genetic Risk Score Predicts Prostate Cancer Drug Response
Metastatic castration-resistant prostate cancer is when the cancer has spread to parts of the body other than the prostate, and it is able to grow and spread even though drugs or other treatments to lower the amount of male sex hormones are being used to manage the cancer. More...20 Apr 2020

Novel Inherited Mutation Predisposes Children to Medulloblastoma
Cancer genomics has revealed many genes and core molecular processes that contribute to human malignancies, but the genetic and molecular bases of many rare cancers remains unclear. Genetic predisposition accounts for 5% to 10% of cancer diagnoses in children. More...16 Apr 2020
SARS-CoV-2 Found in Sputum/Feces After Negative Pharyngeal Specimens
The outbreak of coronavirus disease 2019 (COVID-19) has become a global public health problem. In the absence of a specific therapy or vaccine, timely diagnosis and the establishment of a sufficient isolation period for infected individuals are critical to containment efforts. More...14 Apr 2020

Susceptibility Gene Identified for Idiopathic Pulmonary Arterial Hypertension
Idiopathic pulmonary arterial hypertension (IPAH) is a lung disorder characterized by high blood pressure in the pulmonary arteries. In this instance, “idiopathic” means that the cause of the pulmonary artery hypertension is unknown. More...14 Apr 2020
In Other News
Protein Biomarker Is Early Predictor of Likelihood of Developing Liver Disease
Liquid Biopsy Lung Cancer Screening Method Developed
Circulating RNA Biomarker Predicts Likelihood of Developing Alzheimer’s Disease
Potential Microbial Markers Identified for Cervical Pre-Cancer Progression
Early Tumor Detection by Analysis of Circulating Free DNA Methylation Patterns
Deep Throat SARS-CoV-2 Viral Load Ascertained in Saliva Samples
Rapid, Paper-Based Test Detects Coronavirus in Sewage and Wastewater
Hybrid Liquid Biopsy Platform Enables Tracking and Monitoring of Circulating Tumor Cells
Early Prediction of Resistance to Tyrosine Kinase Inhibitors Reported
Urine-Based Kidney Transplantation Rejection Risk Assay Launched
Genetic Testing Benefits Postmenopausal Women with Breast Cancer
Kidney Disease Reveals DNA Variants Associated with Diabetic Nephropathy
Combined Maternal and Fetal Gene Variants Predict Pre-Eclampsia Risk
Multitarget Stool DNA Predicts Colorectal Neoplasia
Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
Plasma Virome of Brazilians with Unexplained Symptoms of Infection
Increased Membrane Glycoprotein Level Predicts Lung Cancer Metastasis
EGFR Mutation Assay Cartridges Evaluated
Combination of Genetic Signatures Identifies Ultra High Risk Multiple Myelomas
SARS-CoV-2 Detected in Multiple Sample Types
T-cell Monitoring to Predict Risk of Kidney Transplant Failure
NGS Identifies Genomic Characteristics of Pediatric Leukemia
Methylome Analysis for Noninvasive Prostate Cancer Monitoring
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.







