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Molecular Diagnostics

Image: SNRPN (Small nuclear ribonucleoprotein-associated protein N). SNRPN-methylation is used to detect imprinting errors on chromosome 15 (Photo courtesy of Wikimedia Commons)

Novel Blood Test Diagnoses Newborns with Rare Genetic Disorders

A team of Australian researchers has developed a test to screen newborns for three rare genetic disorders simultaneously. More...
01 Feb 2022
Image: The NovaSeq 6000 Sequencing system (Photo courtesy of Illumina)

Transcriptomic Analysis Reveals Proinflammatory Signatures Associated with AML Progression

Acute myeloid leukemia (AML) is believed to arise through a combination of genetic alterations and aberrant gene expression patterns caused by genetic and epigenetic changes, which in their composition also determine AML progression and therapy resistance. More...
01 Feb 2022
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Meridian Bioscience Launches Two New Master Mixes That Detect DNA and RNA in Crude Saliva Samples

Meridian Bioscience, Inc. (Cincinnati, OH, USA) has launched two new master mixes that detect DNA and RNA in crude saliva samples. More...
01 Feb 2022
Image: Micrograph of prostate adenocarcinoma, acinar type, the most common type of prostate cancer (Photo courtesy of Wikimedia Commons)

Epigenetic Biomarkers Increase Sensitivity of Prostate Cancer Liquid Biopsy Diagnostic Tests

A team of Austrian researchers identified additional epigenetic biomarkers that will upgrade the diagnosis of advanced prostate cancer by increasing the sensitivity of liquid biopsy analysis of circulating tumor DNA. More...
31 Jan 2022
Image: The ultrarapid genome sequencing pipeline, indicating all processes from sample collection to a diagnosis. Vertically stacked processes are run in parallel (Photo courtesy of Stanford University)

Ultrarapid Nanopore Genome Sequencing in a Critical Care Setting

A genetic diagnosis can guide clinical management and improve prognosis in critically ill patients, and much effort has gone into developing methods that result in rapid, reliable results. More...
27 Jan 2022
Image: BreathBiopsy Collection Station (Photo courtesy of Owlstone Medical)

Novel Breath-Based Diagnostics Could Indicate Early Rejection of Organs in Lung Transplant Patients

SQI Diagnostics Inc. (Ontario, Canada) and Owlstone Medical (Cambridge, UK) have signed a Memorandum of Understanding (MOU) to work together on the discovery, development and commercialization of breath-based biomarkers relating to invasive aspergillus lung infection and lung transplant rejection. More...
26 Jan 2022
Image: The High Capacity RNA-to-cDNA Kit is a streamlined reverse transcription kit designed for optimum performance with TaqMan Gene Expression Master Mix, Power SYBR Green PCR Master Mix, and other PCR enzymes (Photo courtesy of Thermo Fisher Scientific)

Melanoma Test Offers Reassurance of Low Risk of Cancer Spread

Cutaneous melanoma is an aggressive form of skin cancer with an increasing worldwide incidence, particularly in the younger population. Although treatment for patients with metastatic melanoma has improved remarkably in the last decade, principally with targeted therapies and immune checkpoint modulators, there are still no consistently beneficial treatments for patients with metastatic disease. More...
25 Jan 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.