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Molecular Diagnostics

Image: The FUJI DRI-CHEM IMMUNO AG1 analyzer (Photo courtesy of FUJI FILM).

Rapid Antigenic Diagnostic Test Validated for Ebola Virus Disease

 Hemorrhagic fever outbreaks are difficult to diagnose and control in part because of a lack of low-cost and easily accessible diagnostic structures in countries where etiologic agents are present. Initial clinical symptoms are common and shared with other endemic diseases such as malaria or typhoid fever. More...
13 Feb 2020
Image: Structure of the lipocalin 2 (LCN2) protein (Photo courtesy of Wikimedia Commons)

Lipocalin 2 Identified as Biomarker for Differential Diagnosis of Vascular Dementia

 Results obtained by a study conducted by several European research institutes suggest that lipocalin 2 is a promising biomarker for the differential diagnosis of vascular dementia. More...
12 Feb 2020
Image: Illustration of a 2019- novel coronavirus (nCoV) virion (Photo courtesy of Alissa Eckert, MS/CDC).

CDC Provides Test Protocol for Novel Coronavirus

 The US Centers for Disease Control and Prevention (Atlanta GA, USA) has publicly posted its assay for novel coronavirus 2019-nCoV and is now developing the test into kits. The CDC diagnostic test is a reverse transcriptase real-time PCR (rRT-PCR) assay developed for respiratory and blood serum samples. The protocol to make the assay has been made publicly available. More...
11 Feb 2020
Image: Workflow of cancer personalized profiling by deep sequencing (CAPP-Seq) circulating tumor-DNA analysis (ctDNA) (Photo courtesy of Rashedul Islam Rony, PhD).

Lung Cancer Liquid Biopsy Guides MRD-Directed Adjuvant Therapy

 Minimal residual disease (MRD) is the name given to small numbers of leukemic cells (cancer cells from the bone marrow) that remain in the person during treatment or after treatment when the patient is in remission or have no symptoms or signs of disease. More...
11 Feb 2020
Image:  Human sperm stained for semen quality testing in the clinical laboratory (Photo courtesy of Wikimedia Commons)

Detection of Pathogenic Microorganisms in Semen by Sequencing Sperm RNA

 Advanced sequencing of sperm RNA was used to detect genetic material from microorganisms that were present as contaminants in the associated semen. More...
11 Feb 2020
Image: Summary of findings in primary BRCA2mut/+ breast tissues: Epithelial progenitor cells of heterozygous germline BRCA2 carriers exhibit DNA damage, failed replication stress, and damage responses, together with attenuated apoptosis. Loss of heterozygosity (LOH) analyses suggests that these findings may reflect a haploinsufficient phenotype for BRCA2 in vivo (Photo courtesy of Massachusetts General Hospital).

Single-Cell Sequencing Identifies Breast Cancer Risk

 Women harboring heterozygous germline mutations of BRCA2 have a 50% to 80% risk of developing breast cancer, yet the pathogenesis of these cancers is poorly understood. Breast cancers arising in women who inherit heterozygous mutations in BRCA2 are associated with a high prevalence of genomic alterations and aggressive clinical behavior. More...
10 Feb 2020
Image: The flexible NextSeq 550 System offers a seamless transition between high-throughput sequencing and array scanning (Photo courtesy of Illumina).

Novel Enrichment Technology Indicates High Performance for Multi-Cancer Detection

 Breast, lung, pancreatic, and prostate cancer make up 41% of the cancer incidence in the USA. Early detection and a deep understanding of each cancer remain critical for implementing the highest quality of care. More...
10 Feb 2020
New
Gold Member
Blood Gas Analyzer
GEM Premier 7000 with iQM3
Antipsychotic TDM Assays
Saladax Antipsychotic Assays
New
Dengue Test
Lab Rapid Dengue NS1
New
Gold Member
Serological Pipet Controller
PIPETBOY GENIUS


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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