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Molecular Diagnostics

Image: Absence of nuclear immunohistochemical staining of MSH2 protein (A) and presence of MLH1 protein (B) in urothelial cell carcinoma of the urinary bladder of a patient carrying a germline MSH2 mutation. Observe the nuclear staining in stromal cells as an internal control (Photo courtesy of Radboud University Nijmegen Medical Centre)

Simple Urine Test Detects Urothelial Cancers in Lynch Syndrome Patients

Lynch Syndrome (LS) is an inherited genetic disorder that carries a high risk of cancer. LS is caused by mutations affecting MLH1, MSH2, MSH6 or PMS2 genes. More than one in 300 people have LS but most do not know it and that is equivalent to more than 2,300 new cases every year in the UK. More...
24 Nov 2021
Illustration

Same Day DNA Sequencing-Based Test Identifies Secondary Infections in COVID-19 Patients

A same-day test has been shown to successfully identify secondary infections in COVID-19 patients in the intensive care unit (ICU) within hours rather than days. More...
23 Nov 2021
Image: Dr. Lee Harrison and Alex Sundermann load samples for genomic sequencing (Photo courtesy of Nathan Langer/UPMC)

AI Combined with Genomic Surveillance Beats Humans at Detecting Infectious Disease Outbreaks in Hospital Settings

By coupling machine learning with whole genome sequencing, scientists have greatly improved the quick detection of infectious disease outbreaks within a hospital setting over traditional methods for tracking outbreaks. More...
23 Nov 2021
Image: Molecular model of chymotrypsinogen. Increased levels of chymotrypsinogen B1 (CTRB1) were associated with decreased risk of type I diabetes (Photo courtesy of Wikimedia Commons)

Novel Protein Biomarkers Linked to Risk of Developing Type I Diabetes

A recent study identified three novel circulating proteins associated with type I diabetes risk and that could potentially serve as diagnostic biomarkers for the disease. More...
22 Nov 2021
Image: The LymphoTrack Assay kits are designed for the identification of gene rearrangements in hematologic samples utilizing NGS technologies (Photo courtesy of Invivoscribe)

Next-Generation Sequencing Strategy Validated for MRD Monitoring in Multiple Myeloma

Multiple myeloma (MM) is a plasma-cell dyscrasia characterized by the accumulation of plasma cells in the bone marrow that produces an excess of clonal immunoglobulins (M-protein or monoclonal component). More...
18 Nov 2021
Image: POC pathogen detection system (Photo courtesy of Fraunhofer IPM)

POC System that Requires Single DNA Molecule for Rapid Detection of Multidrug-Resistant Pathogens Unveiled at MEDICA 2021

A new compact device for detecting multidrug-resistant pathogens that performs all stages of the reaction automatically and provides a result within one hour using one single DNA molecule was unveiled at MEDICA 2021. More...
18 Nov 2021
Image: Pipetty Electronic Pipette (Photo courtesy of ICOMES LAB Co., Ltd.)

Icomes Lab Demonstrates World's Smallest and Lightest Electronic Pipette for PCR Testing at MEDICA 2021

ICOMES LAB Co., Ltd. (Iwate, Japan) demonstrated the world's smallest and lightest electronic pipette with a length of 135mm and a weight of 75g at MEDICA 2021. More...
18 Nov 2021
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Autoimmune Liver Diseases Assay
Microblot-Array Liver Profile Kit
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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