Clinical Chemistry


Alzheimer Disease CSF Biomarker Used in Clinical Setting
Analysis of cerebrospinal fluid (CSF) is one of the key tools for the state-of-the-art differential diagnosis of dementias. Dementia due to Alzheimer’s disease (AD) is characterized by elevated CSF levels of total Tau (tTau) and phospho-181-Tau (pTau) and low CSF amyloid-β42 (Aβ42). More...27 Mar 2018



Troponin I Levels Predict Coronary Artery Disease Severity
Although coronary artery disease (CAD) may be present early in life, its progression over time is highly unpredictable. Coronary atherosclerosis can progress at variable rates, ranging from a gradual increase in luminal narrowing to an abrupt progression to total luminal occlusion. More...20 Mar 2018


Dried Blood Spot Protein Assays Evaluated for Biochemistry
Dried blood spots have long been used in applications like newborn testing, but they have yet to make their way into clinical proteomic testing in a significant way. This is due in part to the fact that conventional immunoassays, which are widely used for protein measurements in the clinic, are poorly suited to analyzing dried blood spots given their limited sample volume. More...15 Mar 2018
In Other News
Biological Markers in Tears May Diagnose PD
Plasma Metabolite Profile and Gut Microbiota Connected to Obesity
Parent Age May Help Predict AD Biomarker Levels
Blood Test Biomarkers Diagnose Autism Accurately
Depression Linked to Reduced Arginine Levels
Enzymatic Assay Developed for Ether Phospholipids in Plasma
Mass Spectrometer Test Developed for Multiple Myeloma
Blood Test Approved for Adult Traumatic Brain Injury
AKI Biomarker Described for Pediatric Malaria
Plasma Markers Predict Brain Amyloid Burden in AD
C-Reactive Protein Assessed for Albuminuria Severity
Blood Test Plus Ultrasound Enhances Liver Cancer Detection
Blood Test Helps Identify CV Patients Most at Risk
Mass Spectrometry Test Launched for Newborn Disorders
Metabolite Biomarkers of Chronic Typhoid Carriage Detected
POC Testing Evaluated for Fecal Calprotectin
Glycan-Attaching Enzyme Defines Colon Cancer
New Biosensor Monitors Glucose in Tears and Sweat
Mutation Found in Families with Contradictory Blood Sugars
New Guidelines Issued for Diabetes Testing
New Cholesterol Calculation May Avoid Fasting
Serum Albumin Level Predicts Serious HIV Events
Blood Gas Analyzers for POC Validated
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.