Clinical Chemistry
Diagnostic Process Detects Alzheimer’s Years before Symptoms Appear
Alzheimer's disease (AD) pathology is accompanied by misfolding of amyloid-β (Aβ) and tau from monomeric into β-sheet–enriched pathogenic species. This process is suggested to precede about 10 to 15 years before clinical onset of the disease. More...23 May 2019
Lower HbA1c Levels Seen in Diabetic Liver Disease Patients
Diabetes is a leading cause of liver disease, with cirrhosis responsible for a considerable number of deaths in people with diabetes in the USA. The association is mediated by multiple mechanisms including dyslipidemia and altered hepatic fatty acid processing. More...23 May 2019
Biomarkers Predict Total Joint Replacements in Osteoarthritis Patients
Osteoarthritis (OA) in major joints ultimately leads to joint failure for which the only curative treatment is total joint replacement. This procedure is associated with risk of complications and approximately 20% continue to experience pain. More...22 May 2019
Primary Fatty Amides Produce Blood Test for Alzheimer Disease
Neurodegenerative dementias are characterized by a progressive decline in cognitive function and memory performance. Alzheimer's disease (AD) is the most common of the neurodegenerative dementias making it a major source of global morbidity and mortality. More...21 May 2019
Blood Test May Predict Cardiovascular Disease
According to the latest statistics from the American Heart Association (AHA), almost half of the people living in the USA have some form of cardiovascular disease. In fact, according to 2016 figures, 121.5 million adults in the USA, or 48% of the entire population, have cardiovascular disease (CVD), which is a cluster of conditions that includes hypertension. More...16 May 2019
Randox Unveils an Assay for the Rapid Measurement of Small Dense LDL Cholesterol (sdLDL-C)
A kit for the automated measurement of small dense low-density lipoprotein cholesterol (sdLDL-C) is now available with dedicated controls and calibrators available and instrument-specific applications for use with a wide range of biochemistry analyzers. More...13 May 2019
Blood Protein Signature Reported for Diabetic Kidney Disease
Diabetic nephropathy or diabetic kidney disease (DKD), is a result of vascular abnormalities that accompany diabetes and increases mortality risk. Furthermore, diabetes mellitus is a main risk factor for end-stage renal disease, the most advanced stage of kidney disease. More...09 May 2019
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In Other News
Glucose Test in Pregnancy Can Detect CV Risk
High HbA1c Levels Linked to Pregnancy Risks
Low Serum Creatinine Associated with Diabetes Risk
Parallel Assays Developed for CSF Alzheimer's Disease Proteins
C-Peptide Responsiveness May Explain HbA1c Variation
B-Type Natriuretic Peptide Sandwich Immunoassay Evaluated
HDL‐C Levels Associated with Harmful CKD Progression
Capillary and Venous Lactate Compared in ED Patients
HbA1c Point-of-Care Test Reliably Diagnoses Diabetes
Storage Conditions Affect Urinary Albumin and Creatinine
New Automated Assay Measures Levels of sPLA2-IIA
C-Peptide Test Essential after Type 1 Diabetes Diagnosis
Increased Hormones Lead to Idiopathic Intracranial Hypertension
Signature Odor of Parkinson's Disease Discovered
Metabolic Fingerprinting Diagnoses Fibromyalgia
HbA1c Test Misses Many Cases of Diabetes
Pathology Differences Distinguish CTE from Azheimer's Disease
Blood Test to Diagnose Heart Attacks Can Be Misleading
Urine Test Allows for Rapid Preeclampsia Diagnosis
Diabetics Experience High Blood Sugar after Joint Surgery
Proteomics Profile Early Detection Ovarian Cancer
Urinary KIM-1 Concentration Interpreted in Detecting AKI
Biochemical Monitoring Devices Measure Analytes in Perspiration
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.