Clinical Chemistry

Biomarkers Evaluated for Lung Disease Severity in Cystic Fibrosis
Cystic fibrosis (CF) is one of the most common life-shortening monogenic disorders amongst European-derived populations currently affecting more than 85,000 patients worldwide. The diagnosis of CF is based on consensus clinical and laboratory criteria. More...22 Jun 2020

Metabolite Profiling Reveals Predictive Biomarkers for Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS) is characterized by stiff muscles, muscle twitching, and gradually worsening weakness due to muscles decreasing in size. It may begin with weakness in the arms or legs, or with difficulty speaking or swallowing. More...11 Jun 2020

Serum Free Thiols Predict Cardiovascular Events
Cardiovascular disease (CVD) is among the leading causes of morbidity and mortality globally, and during the past decade, the number of CVD-associated deaths has increased by 12.5%. Free thiols associate with favorable disease outcomes in many patient cohorts, and the current hypothesis is that oxidative stress might also play an important role in cardiovascular disease. More...08 Jun 2020

Urine Testing Method Developed for Ureterolithiasis
Ureterolithiasis (nephrolithiasis or kidney stones) is a disease affecting the urinary tract. Kidney stones occur due to buildup of certain salts and minerals that form crystals, which in turn stick together and enlarge to form a hard mass in the kidneys. The stones move into the urinary tract and can cause blood in the urine, considerable pain and blockages in the urinary system. More...03 Jun 2020

Glucose Levels Linked to Maternal Mortality Even in Non-Diabetic Women
The prevalence of diabetes mellitus (DM) and obesity have rapidly increased worldwide. Serum glycated hemoglobin A1c (HbA1c), expressed as an absolute percent (e.g., 5.5%), offers a convenient and representative measure of average blood glucose control among individuals with DM. More...02 Jun 2020


In Other News
Elevated Metal Ion Level Detects Defective Hip Arthroplasty Implants
Soluble Transferrin Receptor Investigated in Iron Deficiency Anemia
Biomarker Data Improves Risk Prediction for Pancreatic Cancer
Blood Biomarkers Help Diagnose Parkinson's Disease
Salivary Molecular Spectroscopy Used to Monitor Diabetes
Biomarker Panel Evaluated for Primary Hyperoxaluria Patients
HPLC Method Developed for Vitamin B6 Quantitation
Elevated Vitamin-B12 Level Lowers Risk of Parkinson’s Disease Dementia
Novel Glycoprotein Biomarker Evaluated for Liver Fibrosis
C-Reactive Protein Predicts Neurological Outcomes of Subarachnoid Hemorrhage Patients
Novel Method Developed to Estimate LDL Particle Size
Factors Associated with ARDS in COVID-19 Identified
Higher Tenascin-C Levels Associated with Cardiovascular Disease
Kidney Disease Reveals DNA Variants Associated with Diabetic Nephropathy
Serial Procalcitonin Measurements Utilized in Hospitalized Community-Acquired Pneumonia
Endothelial Function Biomarker Improves Sepsis Patients Risk Stratification
Adiponectin Linked to Cancer Risk in Diabetes
Altered Glycosylation Associated with Dedifferentiation of Hepatocellular Carcinoma
Noninvasive Urine Test Developed for Prostate Cancer
Predictors Evaluated for Microalbuminuria in Type 2 Diabetes
Automated Enzymatic Method Quantifies Pyruvate Kinase in Erythrocytes
Regular Thyroid Testing Recommended Regardless of Diabetes Type
Glucose Point-of-Care Measurements Evaluated for Gestational Diabetes
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.