BioResearch
Researchers Aim to Reduce Variability of Gene Therapy Vectors
A recently published study illuminated a previously unknown aspect of adeno-associated virus capsid heterogeneity and highlighted its importance in the development of these vectors for use in gene therapy applications. More...30 Oct 2018
Candidate Anticancer Drug Effectively Treats Drug-resistant Pancreatic Cancer
A candidate anticancer drug derived from the medicinal bark of a Chinese tree was shown to effectively treat drug-resistant pancreatic cancer alone or in combination with other pancreatic cancer chemotherapeutic drugs. More...29 Oct 2018
Gene Mutation Reduces Glucose Uptake and Premature Mortality
A loss-of-function mutation in a gene in the digestive tract reduces glucose uptake from ingested food, which helps to protect the individual from diabetes, obesity, heart failure, and premature mortality from these disorders. More...25 Oct 2018
Long Non-Coding RNA Identified Modulates Synaptic Morphology and Function
A specific long non-coding RNA that exists in the hippocampal neurons of the brain was found to be enriched in the cells' nuclei and was shown to be necessary for modulating synaptic communication, synapse density, synapse morphology, and dendritic tree complexity. More...24 Oct 2018
Gene Editing Used to Mimic Dysfunctional Neurodegenerative Calcium Transport
A team of neurodegenerative disease researchers working with various Alzheimer's disease model systems has found that expression levels of the STIM1 gene in brain tissues decreased with the progression of neurodegeneration. More...22 Oct 2018
Screening Technique Finds Endothelial Cells Targeted by Nanoparticles
A recently developed technique allows researchers to identify lipid nanoparticles that preferentially target endothelial cells – rather than liver cells – for transport of the components of the CRISPR/Cas9 gene-editing tool. More...18 Oct 2018
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In Other News
Research Determines Why Different Cancers Display Similar Profiles
Molecular Scaffolds Promise Drug Synthesis in Breast Cancer Treatment
Targeted Delivery of Resveratrol Prevents Lung Cancer in Model
Genetically Engineered Zika Virus Slows Tumor Growth in Model
Mechanism Identified for Control of Nuclear Pore Complexes
Candidate Cancer Drug Blocks Growth and Reverses Drug Resistance
Genome Editing Used to Correct Mitochondrial Mutations
Mitochondrial Peptide Protects Brain from Age-Related Dementias
Nanoplatform Overcomes Kidney Cancer Drug Resistance
In Vitro Technique Details Cancer Cell Attachment and Spread
Antibiotic Characterized for Drug-Resistant Strains of TB
Novel Approach Brings Personalized Melanoma Treatment Closer to Reality
Deleting Liver Protein Improves Glucose Metabolism
Caspase-2 Drives Progression of Fatty Liver Disease
Approved Drugs Effectively Suppress Growth of Lethal Pathogen
Vaccination with Receptor Protein Protects Mice against AD
Early Stages Proceed in Development of Acne Vaccine
Gene Editing Reverses DMD Muscle Damage in Model
Nucleic Acid Therapy Effective in Inflammatory Bowel Disease Model
Map Reveals How Zika Virus Associates with Host Cell Proteins
Polysome Screen Identifies Cancer Related MicroRNAs
Blocking Glucose Metabolism Prevents Development of Metabolic Syndrome
Study Describes Use of Malaria Parasite Protein to Collect CTCs
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
