LabMedica

Download Mobile App
Recent News Expo Clinical Chem. Molecular Diagnostics Hematology Immunology Microbiology Pathology Technology Industry Focus

Upgraded Software Enhances Confidence in Flow Cytometry for Hematology Labs

By LabMedica International staff writers
Posted on 20 May 2013
Print article
An innovative software solution, with cutting-edge image analysis technology for use with a specialized 5-color reagent, has been upgraded to further enhance the performance of flow cytometry in hematology laboratories.

Beckman Coulter Inc. (Pasadena, CA, USA) introduces an advanced version of the innovative “CytoDiff CXP” Autogating Software. The software is an integral part of the company’s unique HematoFlow solution1 —combining diagnostic reagent, hematology and flow cytometry hardware, and IT expertise.

The introduction of Version 2 CytoDiff CXP Autogating software is designed to provide added confidence in the use of flow cytometry in the routine hematology lab for the autovalidation of abnormal samples. Easy-to-use, the advanced Version 2 software further improves sub-population classifications. New features include greater precision in the removal of potential interference and metrics that provide a new “confidence level” on population classification. The new software simplifies the review process, making it easier to validate results with greater certainty.

HematoFlow with the CytoDiff five-color antibody cocktail and CXP Autogating Software make it possible to use the precision of flow cytometry to deliver extended white blood cell (WBC) differential results with far greater consistency than manual microscopic assessment. The CytoDiff five-color antibody cocktail uses six monoclonal antibodies to establish the differential. “HematoFlow with CytoDiff CXP Autogating Software offers enhanced performance by delivering flow cytometry expertise alongside cutting edge image analysis technology applied to each of the multiple population classifiers,” explained Dr. Josee Naegelen, hematology marketing manager, Beckman Coulter Diagnostics Global Product Management and Strategy.

“The routine use of flow cytometry for validating abnormal samples can improve workflow and turnaround time as well as providing access to additional diagnostic information for patients,” said Dr. Naegelen. “This has a significant impact on the lab, enabling it to handle increasing workloads with greater confidence.”

Laboratories are already working with Beckman Coulter to increase confidence in the routine use of flow cytometry in the hematology process for validating abnormal samples. Hospitals including University Hospital, Rennes and Bordeaux (France), Erasme University Hospital, Brussels (Belgium), and several private labs are successfully adopting this approach. They are using Beckman Coulter’s FC 500 flow cytometer and the CytoDiff reagent to establish the extended flow WBC differential, detecting and quantifying normal and abnormal population subsets.

[1] CytoDiff is not available in the United States and other geographies.

Related Links:

Beckman Coulter


Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
Magnetic Bead Separation Modules
MAG and HEATMAG
Anti-Cyclic Citrullinated Peptide Test
GPP-100 Anti-CCP Kit
New
Gold Member
TORCH Panel Rapid Test
Rapid TORCH Panel Test

Print article

Channels

Clinical Chemistry

view channel
Image: The 3D printed miniature ionizer is a key component of a mass spectrometer (Photo courtesy of MIT)

3D Printed Point-Of-Care Mass Spectrometer Outperforms State-Of-The-Art Models

Mass spectrometry is a precise technique for identifying the chemical components of a sample and has significant potential for monitoring chronic illness health states, such as measuring hormone levels... Read more

Hematology

view channel
Image: The CAPILLARYS 3 DBS devices have received U.S. FDA 510(k) clearance (Photo courtesy of Sebia)

Next Generation Instrument Screens for Hemoglobin Disorders in Newborns

Hemoglobinopathies, the most widespread inherited conditions globally, affect about 7% of the population as carriers, with 2.7% of newborns being born with these conditions. The spectrum of clinical manifestations... Read more

Immunology

view channel
Image: The AI predictive model identifies the most potent cancer killing immune cells for use in immunotherapies (Photo courtesy of Shutterstock)

AI Predicts Tumor-Killing Cells with High Accuracy

Cellular immunotherapy involves extracting immune cells from a patient's tumor, potentially enhancing their cancer-fighting capabilities through engineering, and then expanding and reintroducing them into the body.... Read more

Microbiology

view channel
Image: The T-SPOT.TB test is now paired with the Auto-Pure 2400 liquid handling platform for accurate TB testing (Photo courtesy of Shutterstock)

Integrated Solution Ushers New Era of Automated Tuberculosis Testing

Tuberculosis (TB) is responsible for 1.3 million deaths every year, positioning it as one of the top killers globally due to a single infectious agent. In 2022, around 10.6 million people were diagnosed... Read more