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Pathology

Image: An MRI analysis – Lack of SatM resulted in resistance to fibrosis in mice (Image courtesy of laboratory of Prof. Akira, IFReC, Osaka University).

Abnormal Immune Cells Involved in Causing Fibrosis

Using a mouse model, researchers have discovered a form of atypical monocyte as well as a committed progenitor that are involved in development of fibrosis. More...
10 Jan 2017
Image: The SpectraMax M Series multimode microplate reader (Photo courtesy of Molecular Devices).

Multiple Sclerosis Associated with Leaked Hemoglobin in Brain

In multiple sclerosis (MS), progressive disease develops in over half of those who present with an initial relapsing phase, known as secondary progressive MS (SPMS), but can also present as primary progressive MS (PPMS). More...
05 Jan 2017
Image: Midazolam, a drug used to give symptom relief in palliative care to terminal patients (Photo courtesy of WebMD).

Blood Test Predicts How Long Cancer Patients Will Survive

Survival evaluations can determine whether or not pharmacological treatment should be given. Cytotoxic chemotherapy would rarely be prescribed in a patient unlikely to survive beyond several weeks because of unpleasant side effects. More...
05 Jan 2017
Image: The Biomark microfluidic system for polymerase chain reactions (Photo courtesy of Fluidigm).

DNA Levels in Blood Correlated with Ovarian Cancer Outcomes

The development of blood biomarkers that can be used for early detection of cancer or to measure tumor burden and response to treatment is a major goal of translational cancer studies across all cancer types. More...
04 Jan 2017
Image: A histopathology of a skin-punch biopsy specimen in a patient with systemic sclerosis (Photo courtesy of Dr. Soumya Chatterjee, MD, MS, FRCP).

Gene Activity Predicts Progression of Autoimmune Disease

A new diagnostic tool has been designed for a rare and deadly autoimmune disease called systemic sclerosis that affects the skin and internal organs and the disease affects about 100,000 people in the USA. More...
04 Jan 2017
Image: High molecular weight tau bands (about 80kDa) can be visualized, with greater immunoreactivity, in patients with AD compared with healthy subjects (Photo courtesy of Dr. Ricardo B. Maccioni, University of Chile).

Assessment of Tau Protein Status for Early Detection of Alzheimer's Disease

The ratio of normal to aggregated tau protein found in blood platelets has been suggested as a biomarker that could be used for the early detection of Alzheimer's disease. More...
03 Jan 2017
Image: A histopathology of a non-small cell lung carcinoma (Photo courtesy of Librepath).

Highest Sensitivity Liquid Biopsy Test Introduced for Lung Cancer

Approximately 20% of non-small cell lung cancer (NSCLC) patients test positive for an epidermal growth factor receptor (EGFR) driver mutation and receive EGFR Tyrosine Kinase Inhibitor (TKI) therapy, but unfortunately, most will develop a resistance to this type of therapy. More...
03 Jan 2017
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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