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Pathology

Image: A human malignant melanoma cell viewed through a fluorescent, laser-scanning confocal microscope. Invasive structures involved in metastasis appear as greenish-yellow dots, while actin (green) and vinculin (red) are components of the cell’s cytoskeleton (Photo courtesy of Vira V. Artym, PhD, PMP).

Early Stage Melanoma Identified by Simple Blood Test

Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. Melanomas typically occur in the skin but may rarely occur in the mouth, intestines, or eye. More...
20 Sep 2017
Image: The MasSpec Pen rapidly and accurately detects live cancer during surgery, helping improve treatment and reduce the chances of cancer recurrence (Photo courtesy of the University of Texas at Austin).

Handheld Mass Spectrometer Identifies Cancer Tissue in Seconds

A team of scientists and engineers has invented a powerful device that rapidly identifies living cancerous tissue, giving surgeons precise diagnostic information about what tissue to cut or preserve. More...
19 Sep 2017
Image: A scanning electron micrograph (SEM) of Epstein-Barr virus budding in a B cell (Photo courtesy of The Multiple Sclerosis Discovery Forum).

Epstein-Barr Virus Increases Risk of MS

While being infected at a young age with Epstein-Barr virus generally causes few, if any, symptoms, delayed exposure into adolescence or adulthood can cause infectious mononucleosis with symptoms that can be quite severe. More...
15 Sep 2017
Image: Common tumor markers used in the diagnosis of cancer (Photo courtesy of Health Education Library).

Tumor Marker Tests Overused in Primary and Secondary Care

A tumor marker is a biomarker found in blood, urine, or body tissues that can be elevated by the presence of one or more types of cancer. The vast majority of tumor marker tests in primary and secondary care may not be necessary as the tests assisted with a cancer diagnosis in just 2% of patients. More...
15 Sep 2017
Image: The NanoDrop 1000 spectrophotometer used for quantification and purity assessment of RNA samples (Photo courtesy of Thermo Fisher Scientific).

Blood Test Predicts Prostate Tumor Resistance

Prostate cancer (PCa) is the most common cancer and the third leading cause of cancer death among European men. In metastatic PCa progression from a hormone-sensitive state to castration resistance under androgen deprivation therapy marks the transition to the lethal phenotype of the disease. More...
07 Sep 2017
Image: A diagram for the basis of the MedOncAlyzer 170 panel (Photo courtesy of Exosome Diagnostics).

Liquid Biopsy Panel Yields Complete Molecular Profile

The first liquid biopsy pan-cancer panel that simultaneously interrogates exosomal ribonucleic acid (exoRNA) and circulating tumor DNA (ctDNA) in a single assay has been launched. More...
06 Sep 2017
Image: New AI technology may help detect melanoma skin cancer earlier than current methods and to help reduce the number of unnecessary biopsies (Photo courtesy of Deposit Photos).

AI Could Help Identify Early Skin Cancer

Newly developed technology uses artificial intelligence (AI) to help detect melanoma skin cancer earlier than current methods and to help reduce the number of unnecessary biopsies. The AI-based method employs machine-learning software to analyze images of skin lesions and to provide doctors with objective data on telltale biomarkers of melanoma. More...
05 Sep 2017
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.