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Immunology

Image: A collection of whole saliva by the Salivette (absorbent) method. (a) Saliva is collected by chewing a cotton wool swab. (b) The swab containing saliva is placed in the tube of Salivette. (c) Centrifugation of the assemblage. (d) Saliva is separated from the swab and is ready for analysis (Photo courtesy of Sarstedt).

Optimized Immunoassays Detect HBV in Oral Fluid Samples

It is estimated that there are 257 million chronic hepatitis B (HBV) carriers worldwide, which highlights the substantial health, social, and economic burden of HBV. Screening of infected, cured and vaccinated individuals is necessary to identify the presence of chronically infected reservoirs, immune and susceptible individuals. More...
05 Sep 2019
Image: Aspergillus (Photo courtesy of Kateryna Kon / Fotolia.com).

Novel ELISA Detects Invasive Aspergillosis

Aspergillus spp. is a ubiquitous sac fungus, which is found in soil or compost or on damp walls. Inhalation of spores can lead to severe infections in individuals with a weakened immune system. More...
05 Sep 2019
Image: The CFX96 Touch RT-PCR detection system (Photo courtesy of Bio-Rad Laboratories).

Enterovirus Antibodies Detected in Acute Flaccid Myelitis Patients

Neurotropic enteroviruses (EVs), such as poliovirus, have long been associated with paralytic disease. Acute flaccid myelitis (AFM) has caused motor paralysis in more than 560 children in the United States since 2014. More...
28 Aug 2019
Image: Human pancreatic islet stained with glucagon antibody (red) and insulin antibody (blue). Glucagon is produced by alpha cells, while beta cells produce insulin (Photo courtesy of University of Turku).

Signature for Beta-Cell Autoimmunity Predicts Type 1 Diabetes

The appearance of Type 1 diabetes (T1D)-associated autoantibodies is the first and only measurable parameter to predict progression toward T1D in genetically susceptible individuals. More...
28 Aug 2019
Image: The SE280 electrophoresis unit (Photo courtesy of Hoefer).

Troponin Complexes Explored in Acute MI Patients

Acute myocardial infarction is the medical name for a heart attack. A heart attack is a life-threatening condition that occurs when blood flow to the heart muscle is abruptly cut off, causing tissue damage. This is usually the result of a blockage in one or more of the coronary arteries. More...
22 Aug 2019
Image: A circulating tumor cell (arrow) diagnosed by the isolation by size of epithelial tumor cells (ISET) test (The pores of the filter are also visible) (Photo courtesy of Chichiselector).

Circulating Tumor Cells Directly Detected in Blood Samples

Tumor cells circulating in blood are markers for the early detection and prognosis of cancer. However, detection of these cells is challenging because of their scarcity. More...
21 Aug 2019
Image: The VS110 combines microscopy seamlessly with imaging to create a virtual slide that is an exact copy of the real specimen (Photo courtesy of Olympus).

Prognostic Value of Specific Biomarker in Prostate Cancer Authenticated

Prostate cancer (PC) is the most commonly diagnosed cancer in Canadian men. In men with high-risk PC, progression of the disease will lead to biochemical recurrence (BCR), distant metastases, and disease-specific mortality. More...
20 Aug 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.