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Immunology

Image: The CytoFLEX benchtop flow cytometer features up to three lasers for 13-color flow cytometry (Photo courtesy of Beckman Coulter Life Sciences).

Basophil Activation Test Predicts Pediatric Wheezing Prognosis

Although asthma is a common chronic airway inflammatory disease in children, the natural history of asthma remains unknown. It is difficult to diagnose asthma in children aged under five years because of the complexity of wheezing phenotypes at that age. More...
20 Jan 2021
Image: An enzyme-linked immunoassay (ELISA) for serum neurofilament light chain (Photo courtesy of UmanDiagnostics AB).

Increased Serum Neurofilament Light Portend Worse Prognosis in COVID-19

There is emerging evidence for multifarious neurological manifestations of COVID‐19, while little is known whether they reflect structural damage to the nervous system. The most commonly reported neurological manifestations of COVID-19 were myalgia, headache, altered sensorium, hyposmia, and hypogeusia. More...
19 Jan 2021
Image: Fluorescence staining of lymph node containing spegs from patients with cystic echinococcosis (Photo courtesy of University of Ulm).

Immunohistological Detection of Small Particles of Echinococcus Species Evaluated

Echinococcosis, also known as Hydatid Disease, is a life-threatening disease in humans that is caused by the larval stages of the tapeworms Echinococcus multilocularis and Echinococcus granulosus s.l. The two main types of this disease are cystic echinococcosis (CE) and alveolar echinococcosis (AE). More...
18 Jan 2021
Image: Photomicrograph of a section of human skin showing a vacuolar interface dermatitis with dermal mucin. These findings are consistent with discoid skin lesions in lupus dermatitis (Photo courtesy of Nephron).

Serum Pentosidine Levels Measured in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE), is the most common type of lupus. SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. More...
14 Jan 2021
Image: Human Total Angiopoietin ELISA assay (Photo courtesy of Immuno-biological laboratories Co).

Angiopoietin-Like 2 Is a Biomarker for Diabetic Foot Patients

Diabetic foot ulcers (DFUs) are one of the common complications in type 2 diabetes mellitus patients and are chartered by lower extremity vascular obstructions, persistent foot infections, ulcers, and deep tissue destruction. More...
14 Jan 2021
Image: The FLUOstar Omega Microplate Reader (Photo courtesy of BMG LABTECH).

Combination Urinary Biomarker Panel Detects Pancreatic Cancer Earlier

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with only around 9% of patients surviving more than 5 years. Asymptomatic in its initial stages, PDAC is mostly diagnosed late, when already a locally advanced or metastatic disease, as there are no useful biomarkers for detection in its early stages, when surgery can be curative. More...
11 Jan 2021
Image: The Applied Biosystems Veriti 96-Well Thermal Cycler (Photo courtesy of Thermo Fisher Scientific).

Chitotriosidase Expression in Sarcoidosis Limited by Gene Expression

Sarcoidosis is a multisystem granulomatous disease which affects individuals worldwide of all ages irrespective of ethnicity or race. It is often recognized accidentally when a routine chest radiographic picture shows bilateral hilar lymphadenopathy. More...
06 Jan 2021
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.