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Immunology

Image: The NF-light (Neurofilament light) ELISA kit allows fast quantification in less than three hours of neurofilament light in cerebrospinal fluid (Photo courtesy of Andreas Nilsson).

Blood Test Could Predict Multiple Sclerosis Progression

Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease of the central nervous system (CNS), with a highly variable inter-individual disease course. As a result, even if using existing clinical prognostic factors, the forecasting of long-term prognosis is often unreliable and imprecise. More...
01 Jul 2020
Image: MACS cell separation kit uses a combination of superparamagnetic nano-sized beads and a very high magnetic gradient in MACS Columns (Photo courtesy of Miltenyi Biotec).

Diagnostic Assay Developed for Unclassified Severe Combined Immune Deficiency

Severe combined immune deficiency (SCID) is a group of rare hereditary genetic disorders, and is characterized by a total absence of immune system function, including an absence of T-lymphocytes, the white blood cells that play a crucial role in the body's immune defense. More...
30 Jun 2020
Image: CAPILLARYS 2 FLEX PIERCING is an instrument utilizing capillary electrophoresis developed to be versatile while providing a clear-cut and precise protein separation with high throughput (Photo courtesy of Sebia).

Detection Rate of Monoclonal Gammopathy of Undetermined Significance Determined

Multiple myeloma (MM) is a clonal plasma cell malignancy that accounts for approximately 2% of all malignancies. Plasma cells help you fight infections by making antibodies that recognize and attack pathogens. Multiple myeloma causes cancer cells to accumulate in the bone marrow, where they displace healthy blood cells. More...
30 Jun 2020
Image: This illustration reveals ultrastructural morphology exhibited by coronaviruses. Note the spikes that adorn the outer surface of the virus, which impart the look of a corona surrounding the virion, when viewed electron microscopically (Photo courtesy of Centers for Disease Control and Prevention).

Certain Cytokines Not Associated with Severity of COVID-19 Symptoms

The pandemic outbreak of coronavirus disease 2019 (COVID-19) is sharply spreading all over the world. The severity of a viral disease usually is positive association with immune-mediated inflammatory responses. The aggressive and persistent inflammatory response leads to high risk of multiorgan failure and death. More...
24 Jun 2020
Image: Presepsin concentrations (ng/mL) in two severity groups. Black line: sepsis patients; black dotted line: septic shock patients (Photo courtesy of University Hospital for Infectious Diseases in Zagreb).

Presepsin Values Evaluated as Sepsis Severity Markers

Sepsis is a life-threatening condition, with poor and highly variable clinical manifestations, difficult to identify and diagnose. Sepsis has remained a real diagnostic challenge to clinicians, causing millions of death worldwide each year. Early recognition of sepsis is crucial for better disease outcome. More...
23 Jun 2020
Image: The single gene, Cystic Fibrosis Transmembrane Regulator (CFTR) gene is located on the long arm of chromosome 7, and its mutations cause CF (Photo courtesy of Daryl Isaac).

Biomarkers Evaluated for Lung Disease Severity in Cystic Fibrosis

Cystic fibrosis (CF) is one of the most common life-shortening monogenic disorders amongst European-derived populations currently affecting more than 85,000 patients worldwide. The diagnosis of CF is based on consensus clinical and laboratory criteria. More...
22 Jun 2020
Image: The Loa Antibody Rapid Test detects human IgG against a 148-aminoacid sequence of Ll-SXP-1 (Photo courtesy of Drugs & Diagnostics for Tropical Diseases).

Two Serodiagnostic Tests Compared for Loiasis in Non-Endemic Area

Loiasis, the disease caused by the infection with the filarial nematode Loa loa, is transmitted through the bite of tabanid flies of the genus Chrysops. It is endemic in Central and West Africa where, according to the most recent estimates, about 10 million people are infected. More...
18 Jun 2020
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.