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Molecular Diagnostics

Image: The new streamlined approach discovered for diagnosing and treating bowel cancer (Photo courtesy of University of Adelaide).

Streamlined Approach Discovered for Treating Bowel Cancer

More than 4,000 Australians die from bowel cancer each year, and more than 17,000 new cases of this cancer will be diagnosed in 2018. Scientists are working to understand the genetic drivers of bowel cancer, with a special interest in those cancers which are the hardest to treat, and which have the poorest prognosis. More...
02 May 2018
Image: A photomicrograph of a brain tissue specimen revealed the presence of hooklets in a case of cysticercosis, an infection due to the ingestion of eggs of a pork tapeworm, Taenia solium (Photo courtesy of the University of Pennsylvania Medical Center).

Metagenomic Sequencing Can Diagnose Cases of Meningitis

Subacute and chronic meningitis are diagnostically challenging given the wide range of potential infectious, autoimmune, neoplastic, paraneoplastic, parameningeal, and toxic causes. Securing a final diagnosis can require weeks or months of testing or remain unsolved, necessitating empirical treatment approaches that may be ineffective or even harmful. More...
01 May 2018
Image: A positive C. DIFF QUIK CHEK COMPLETE. The assay simultaneously tests for GDH and Toxins A & B providing actionable C. difficile results in less than 30 minutes (Photo courtesy of Alere).

Clostridium difficile Examined by Different Methods

The epidemiology of Clostridium difficile infection (CDI) has shifted in the last decade and is now affecting populations previously at low risk to include healthy adults, peripartum women and young children. More...
30 Apr 2018
Image: The MAST ISOPLEX DNA kit is a ready to use amplification kit, making molecular diagnostics with LAMP easy and efficient (Photo courtesy of Mast Diagnostica).

Treponemal Subspecies Discriminated by LAMP

Human yaws is a tropical skin disease of children caused by the bacterium Treponema pallidum subsp. pertenue (TPE). Skin ulcers are the most characteristic clinical manifestations associated with infection in all three active disease stages, primary, secondary, and tertiary yaws. More...
26 Apr 2018
Image: The QX200 AutoDG Droplet Digital PCR System provides absolute quantification of target DNA or RNA molecules for EvaGreen and probe-based ddPCR applications (Photo courtesy of Bio-Rad).

Molecular Technology Identifies Potential Biomarker for Cancer

For patients with early-stage non-small cell lung cancer (NSCLC), the only recommended treatment option is surgery. After complete resection patients with disease at the same stage experience different outcomes, and within five years a third of patients relapse. More...
26 Apr 2018
Image: The COBAS TaqMan HBV test (Photo courtesy of Roche Diagnostics).

Assay Detects Hepatitis B in Multiple Specimens

Hepatitis B virus (HBV) infection has led to more than 686,000 deaths worldwide per year. Approximately two billion individuals worldwide are infected with HBV and are at risk of developing cirrhosis and hepatocellular carcinoma, which ranks fifth in terms of malignant cancer mortality. More...
25 Apr 2018
Image: A diagram of a normal heart compared to hypertrophic cardiomyopathy (Photo courtesy of the Mayo Clinic).

Genetic Variant Identified As Better Marker for CV Disease

A newly identified subset of a known genetic variant found primarily in individuals of South Asian descent may be a better marker for carriers of heart dysfunction in this population and that individuals with this genetic variant are more likely to develop early signs of hypertrophic cardiomyopathy. More...
24 Apr 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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