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Molecular Diagnostics

Image: The Applied Biosystems 7500 real-time PCR System (Photo courtesy of Thermo Fisher Scientific).

Infections Defined in Urothelial Bladder Tumors

Bladder cancer is estimated to be the 9th most common cancer worldwide and over 90% of bladder tumors are classed as urothelial bladder carcinomas (UBCs), with 75% to 80% presenting at non-muscle-invasive (NMIBC) stages and the remainder presenting at muscle-invasive (MIBC) and metastatic stages. More...
09 Aug 2018
Image: A comparison of healthy bone and osteoporosis (Photo courtesy of PharmacyPedia).

Fracture Risk Predicted with New Genetic Screen

Low bone mineral density (BMD) is the major determinant for osteopenia and osteoporosis, which increase the chances of fragility fracture especially for elderly women. Low BMD is also a risk factor for bone fractures, especially stress fracture. More...
09 Aug 2018
Image: A diagram of the hypothesis for the onset mechanism of childhood steroid-sensitive nephrotic syndrome (Photo courtesy of Kobe University).

Susceptible Genes Identified for Childhood Kidney Disease

Childhood nephrotic syndrome, also known as nephrosis, is an incurable disease with an unknown cause, characterized by large amounts of protein leaving the body in the patient's urine, and protein levels in the bloodstream becoming extremely low. More...
09 Aug 2018
Image: The HaloPlex system enables fast, simple and efficient analysis of genomic regions of interest in a large number of samples (Photo courtesy of Agilent Technologies).

Mutations Identified As Cause for Rare Bone Marrow Disorder

Scientists have helped solve a decades-old mystery about which mutations are responsible for an inherited bone marrow disorder. The answer may allow some children to avoid the risk and expense of bone marrow transplantation, a common treatment for leukemia and bone marrow disorders. More...
09 Aug 2018
Image: The High-Sensitivity Troponin I assay (TnIH) (Photo courtesy of Siemens Healthineers).

New Troponin Assays Receive US Marketing Clearance

Two high precision assays for the measurement of the cardiac marker troponin I (TnIH) have been certified for marketing in the United States. More...
08 Aug 2018

MicroRNA Panel Delivers Thyroid Cancer Diagnosis

A 19 microRNA panel established by using next-generation sequencing classifies indeterminate thyroid nodule samples as being either malignant or benign. More...
08 Aug 2018
Image: A histopathology of adenoid cystic/basal cell carcinoma of the prostate gland (Photo courtesy of Nephron).

Genetic Alterations Correlated to Aggressive Prostate Cancer

Prostate cancer is the second most common cancer among men, and while the disease is often indolent and treatable, some cases are aggressive. Distinguishing between the two could guide treatment decisions. More...
03 Aug 2018
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