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Molecular Diagnostics

Image: The Affymetrix Axiom CEU Genome-Wide Population-Optimized Human Arrays are genotyping panels that offer genetic coverage of rare and common variants for genome-wide disease association studies (Photo courtesy of Thermo Fisher Scientific).

New Risk Variants Identified for Restless Legs Syndrome

As many as one in ten people of European ancestry is affected by restless legs syndrome, in which sufferers feel an overwhelming urge to move, often in conjunction with unpleasant sensations, usually in the legs. More...
24 Oct 2017
Image: An ocular fundus aspect of retinoblastoma (Photo courtesy of Wikimedia).

Liquid Biopsy for Retinoblastoma Discovered

A new study indicates a proof-of-concept for a safe and effective way to derive genetic profile information from a retinoblastoma tumor without removing the eye. More...
24 Oct 2017
DIASOURCE (A Biovendor Company)
Image: An illustration of the human brain cerebral lobes: the frontal lobe (pink), parietal lobe (green), and occipital lobe (blue) (Photo courtesy of Wikimedia).

Genetic Decoding Improved for Neurodevelopmental Disorders

DLG2 gene study as a case in point that will help facilitate future diagnosis of children with neurodevelopmental disorders (NDDs), such as intellectual disability, autism, or early-onset symptoms of psychiatric diseases such as schizophrenia. More...
23 Oct 2017
Image: A photomicrograph showing histopathological image of cerebral glioblastoma (Photo courtesy of Wikimedia Commons).

Biomarker Predicts Cancer Aggressiveness and Drug Susceptibility

Researchers have identified a protein required by some forms of brain cancer (glioblastoma multiforme, GBM) that can be used as a predictive marker for aggressiveness and effective drug response. More...
23 Oct 2017
Image: Mitochondrial DNA comprises the small circular chromosome found inside the mitochondria (Photo courtesy of the U.S. National Human Genome Research Institute).

Mitochondrial DNA Copy Number Improves CVD Risk Prediction

Mitochondrial DNA copy number (mtDNA-CN), which represents the number of mitochondria per cell and number of mitochondrial genomes per mitochondrion, is an indirect biomarker of mitochondrial function that has been identified as an independent predictor of cardiovascular disease (CVD) risk. More...
23 Oct 2017
Image: The Quantiflour dsDNA system for sensitive quantitation of double-stranded DNA in solution (Photo courtesy of Promega).

Bacterial Composition Linked to Breast Cancer

Breast cancer is the second most common cancer in women (after skin cancer) in the USA, where one in eight women will develop the disease in their lifetimes. Bacteria that live in the body is known as the microbiome, and influence many diseases. More...
19 Oct 2017
Image: A diagram of the preeclampsia placenta compared to a normal placenta (Photo courtesy of the University of Dundee).

Preeclampsia Triggered By Gene Activity

Preeclampsia affects around 4% of all pregnancies and its main symptoms are high blood pressure and protein in the urine. If these symptoms reach dangerous levels, delivery must be induced prematurely. More...
19 Oct 2017
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