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Molecular Diagnostics

Image: Structure of the AP2A2 protein (Photo courtesy of Wikimedia Commons)

Genetic Locus with Unique Tandem Repeats Linked to Development of Late-onset Alzheimer’s Disease

 Researchers have discovered evidence of a novel genetic variation linked to the development of late-onset Alzheimer’s disease (AD). More...
02 Dec 2019
Image: The QuantStudio 7 Pro Real-Time PCR System is one of several platforms that the new ChromaCode multi-drug resistant (MDR) panel can be assayed (Photo courtesy of Thermo Fisher Scientific)

Multiplex Panel Debuts for Multi-Drug Resistant Infection Screening

 A multi-drug resistant (MDR) panel detects genetic signatures of resistance to specific antibiotics in pathogens that are commonly thought of as hospital acquired, and is designed to be used as a screening test for infection control and isolation of asymptomatic carriers. More...
28 Nov 2019
Image: Immunofluorescence image of microglial cells stained red with antibody. DNA shown in blue (Photo courtesy of Wikimedia Commons)

Non-coding Regions of the Genome in Microglia Linked to Alzheimer’s Disease Risk

 A recently published paper linked risk of developing Alzheimer’s disease (AD) to enhancers - non-coding DNA regions of the genome - that were present in microglia but not in other types of brain cells such as neurons or astrocytes. More...
28 Nov 2019
Image: Human sperm stained for semen quality testing in the clinical laboratory (Photo courtesy of Wikimedia Commons)

Epigenetic DNA Biomarkers Pinpoint Infertile Men and Predict Potential Success of Treatment

 A molecular analysis method was developed that identifies infertility in men through evaluation of genome wide alterations in sperm DNA methylation. More...
27 Nov 2019
Image: Small particle LDL has been associated with the progression of atherosclerosis and blockage the artery lumen, because it can carry cholesterol into smaller vessels. As atheroma enlarges, the arterial wall ruptures and releases blood clots that lead to narrowing of the artery (Photo courtesy of Wikimedia Commons)

LDL Subclasses Ratio Predicts Cardiovascular Disease Risk More Accurately than LDL-cholesterol Alone

 Measurement of low-density lipoprotein (LDL) cholesterol may a less effective way to predict risk of cardiovascular disease than is the further analysis of the relative proportions of LDL subclasses. More...
27 Nov 2019
Image: Photograph of an iris melanoma (Photo courtesy of Wikimedia Commons)

MicroRNA Panel Distinguishes Benign Moles from Melanoma in the Eye

 A blood test based on a panel of six microRNAs (miRNAs) is able to distinguish non-cancerous nevi from malignant melanoma in the eye. More...
27 Nov 2019
Image: Growth characteristics of rough and smooth phenotypes of Mycobacterium abscessus on 7H11 agar cultured at 37 °C: representative single rough (left) and smooth (right) colonies (Photo courtesy of Hannover Medical School)

Mycobacterium Infection Found in Gastric Patients’ Stomachs

 Development of gastric diseases such as gastritis, peptic ulcer and gastric cancer is often associated with several biotic and abiotic factors. Helicobacter pylori infection is such a well-known biotic factor. However, not all H. pylori-infected individuals develop gastric diseases and not all individuals with gastric diseases are infected with H. pylori. More...
26 Nov 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.