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Molecular Diagnostics

Image: A High Pure PCR template preparation kit (Photo courtesy of Roche Diagnostics).

LAMP Test Rapidly Detects Sexually Transmitted Chlamydia

Chlamydia trachomatis is the leading cause of sexually transmitted diseases (STDs) in females and males in both developed and developing countries, with more than 110 million cases annually. C. trachomatis resists antibiotic treatment and is a cofactor in HIV transmission and human cervical cancer. More...
10 Jan 2019
Image: A diagram showing normal and polycystic ovary syndrome, in the latter the ovaries may develop numerous small collections of fluid (follicles) and fail to regularly release eggs (Photo courtesy of Mayo Clinic).

New Risk Loci Identified for Polycystic Ovary Syndrome

Polycystic ovary syndrome is a disorder characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have metabolic disturbances including insulin resistance and dysregulation of glucose homeostasis. More...
09 Jan 2019
Image: The NovaSeq 6000 sequencing system platform (Photo courtesy of Illumina).

Diverse Chronic Kidney Diseases Diagnosed with Exome Sequencing

Exome sequencing is emerging as a first-line diagnostic method in some clinical disciplines, but its usefulness has yet to be examined for most constitutional disorders in adults, including chronic kidney disease, which affects more than 1 in 10 persons globally. More...
08 Jan 2019
Image: A comparison of OncoScan array CGH assay–derived metastasis potential scores (MPSs) for indolent primary tumor (iPT) and metastasis-prone primary tumor (mPT) samples (Photo courtesy of Albert Einstein College of Medicine).

Rapid Next-Gen Sequencing Method Predicts Prostate Cancer Risks

Prostate cancer is the most commonly diagnosed male cancer and the second leading cause of cancer deaths among men in the USA, with approximately 220,000 new diagnoses and approximately 27,000 deaths each year. More...
08 Jan 2019
Image: Genome-wide human SNP array 6.0 GeneChip (Photo courtesy of Affymetrix).

Metastatic Colorectal Cancer Linked to Transcription Factors

Colorectal cancer (CRC) is a kind of malignant human tumor with high mortality around the world. The incidence of colorectal cancer shows a gender difference and is prone to the elderly. More...
03 Jan 2019
Image: A new screening method for cervical cancer has proven 100% accurate in testing (Photo courtesy of Health News).

Epigenetic Cervical Cancer Test Has Perfect Detection Rate

Human papillomavirus (HPV) ‐based cervical cancer screening requires triage of HPV positive women to identify those at risk of cervical intraepithelial neoplasia grade 2 (CIN2) or worse. More...
02 Jan 2019
Image: The Q Exactive Hybrid Quadrupole-Orbitrap Mass Spectrometer (Photo courtesy of Thermo Fisher Scientific).

Molecular Cause Found for Rare Autoimmune Disorders

It is estimated that more than 20 million Americans suffer from autoimmune disorders. They include rheumatoid arthritis, psoriasis, inflammatory bowel disease, multiple sclerosis, lupus, type 1 diabetes, and dozens of others. More...
01 Jan 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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