Molecular Diagnostics
Presenilin1 Gene Characteristics Used as Alzheimer's Disease Biomarker
Alzheimer's Disease manifests as a familial disease with monogenic inheritance and early onset (Early Onset AD: EOAD), or as a sporadic, multifactorial, late-onset disease (Late Onset AD: LOAD). The latter accounts for more than 90% of all cases and its causes are unknown. More...11 Mar 2020
Blood Test Predicts Response to Immunotherapy in Metastatic NSCLC
Non-small cell lung cancer (NSCLC) patients with higher measures of tumor mutations that show up in a blood test generally have a better clinical response to PD-1-based immunotherapy treatments than patients with a lower measure of mutations. More...10 Mar 2020
Circulating Levels of Phosphorylated Tau Protein Differentiate Alzheimer’s Disease from other Types of Dementia
Elevated levels of circulating phosphorylated tau 181 (pTau181) protein correlate with Alzheimer's disease (AD) and distinguish it from frontotemporal dementia, a condition that is often misdiagnosed as AD. More...10 Mar 2020
High-Throughput Isothermal HPV Test Validated
Human papillomavirus (HPV) is a viral infection that is passed between people through skin-to-skin contact. There are over 100 varieties of HPV, more than 40 of which are passed through sexual contact and can affect the genitals, mouth, or throat. More...10 Mar 2020
Novel 3-Gene Transcriptional Signature Stratified for Tuberculosis Contacts
The causative agent of tuberculosis, Mycobacterium tuberculosis (Mtb) is an obligate pathogen. The highest risk of tuberculosis arises in the first few months after exposure. Early treatment also offers the opportunity to adopt shorter and simpler treatment regimens, limit pathology, and reduce tuberculosis-associated morbidity. More...04 Mar 2020
Increased Levels of Serum Amyloid-beta Linked to Development of Cardiovascular Disease
A new review article has summarized studies, which suggest that the Alzheimer’s disease (AD) biomarker amyloid-beta (Abeta) has a causitive link to other age-related conditions such as cardiovascular disease (CVD). More...04 Mar 2020
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In Other News
Monogenic Hypercholesterolemia Increases Cardiovascular Disease Risk
Leukemic Stem Cell Score Predicts Myelodysplastic Syndrome Prognosis
Identification of a MicroRNA Biomarker Linked to a Childhood Liver Disease
Heterogeneous Populations of Melanoma Circulating Tumor Cells Detected
Researchers Identify Genes Linked to the Development of Monogenic Diabetes
Fetal Cell-Based NIPT Demonstrated by Droplet Digital PCR
Point-Of-Care Molecular Tests Compared for Pediatric Influenza
Genetic Risk Factors Found in Gestational Diabetes
Combining IL-6 Measurement with a Standard Biomarker Panel Improves Diagnosis of Ovarian Cancer
Novel Blood Tests Predict Progression of Parkinson's Disease
Elevated Levels of Certain Immunoproteosome Components Predict Potential Success of Checkpoint Inhibitor Therapy in Melanoma Patients
Proteogenomic Characterization of Endometrial Carcinoma Analyzed
Uric Acid in Saliva Is a Biomarker for Body Fat Accumulation in Adolescents
Ratio of Serum Very-long-chain to Long-chain Ceramides Is Predictive of Dementia Risk
Factor IX Inhibitor Incidence in Pediatric Hemophilia B Examined
Several Genes Linked to Long QT Syndrome Reappraised
Modular Targeted Capture Assay Detects Clinically Significant Oncology Alterations
Assessment of Circulating Tumor Cells Identifyies Stage III Melanoma Patients at Risk for Relapse
Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans
Autonomous Microchannel Analyzer Combines with Smartphone for Off-Site Disease Diagnostics
Protein Panel Predicts Risk for Development of Cerebral Small Vessel Disease
Blood Test Lead to Earlier Detection of Gastrointestinal Cancers
Rapid Antigenic Diagnostic Test Validated for Ebola Virus Disease
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
