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Molecular Diagnostics

Image: Genome-wide association and Mendelian randomization analysis provide insights into the pathogenesis of heart failure (Photo courtesy of WebMD).

Genome-Wide Association Leads to Heart Failure Risk Loci

 Heart failure (HF) affects more than 30 million individuals worldwide and its prevalence is rising. HF-associated morbidity and mortality remain high despite therapeutic advances, with 5-year survival averaging around 50%. More...
23 Jan 2020
Image: Histological immunostaining showing expression of leucine‐rich repeat‐containing G protein–coupled receptor 6 (LGR6) in esophageal squamous cell carcinoma (ESCC) and normal esophageal tissues (NT) (Photo courtesy of Fujian Medical University).

Diagnostic Biomarker Found for Esophageal Squamous Cell Carcinoma

 Esophageal cancer is one of the most common malignant tumors in the world, and its incidence ranks seventh among those of all malignant tumors. Esophageal cancer can be divided into two pathological types: squamous cell carcinoma (SCC) and adenocarcinoma. More...
22 Jan 2020
Image: A smartphone camera is an important component of a new assay system for the detection of E. coli in urine samples (Photo courtesy of University of Bath)

Rapid UTI Test System Combines an Immunoassay with a Smartphone Camera

 A team of British bioengineers has combined a rapid microfluidic fluorescence sandwich immunoassay with a smartphone camera to form an assay system for the diagnosis of urinary tract infections (UTIs). More...
22 Jan 2020
Image: PrimeStore Molecular Transport Medium (MTM) is the first molecular transport device designed to inactivate pathogens and stabilize both RNA and DNA for downstream molecular testing and characterization (Photo courtesy of Longhorn Vaccines and Diagnostics).

Mouth Swab Molecular Test for Tuberculosis Validated

 Clinical investigators are testing an approach being developed to diagnose tuberculosis using mouth swabs, which could become an alternate approach to sample collection methods currently used to do tuberculosis (TB) testing. More...
22 Jan 2020
Image: The Oncotype DX specimen and collection kit for the Breast Cancer Recurrence Score Assay (Photo courtesy of Genomic Health).

21-Gene Recurrence Score Helps Radiation Decision-Making

 A new study shows that a test that physicians commonly used to guide chemotherapy treatment for post-breast cancer surgery patients may also help them decide whether radiation therapy may be of benefit. More...
21 Jan 2020
Image: Abnormal accumulation of tau protein in neuronal cell bodies (arrow) and neuronal extensions (arrowhead) in the neocortex of a patient who had died with Alzheimer's disease (Photo courtesy of Wikimedia Commons)

Acute Sleep Loss Triggers Increase in Plasma Levels of Tau Protein in Young Adults

 A team of Swedish researchers has found that acute sleep loss results in increased blood levels of t-tau protein, a key biomarker for nervous system disorders such as Alzheimer’s disease. More...
20 Jan 2020
Image: This micrograph depicts an atypical, enlarged lymphocyte found in the blood smear from a hantavirus pulmonary syndrome (HPS) patient. This large atypical lymphocyte is an example of one of the laboratory findings, which when combined with a bandemia, i.e., immature white blood cells, and dropping platelet count, is characteristic of HPS (Photo courtesy of Centers for Disease Control and Prevention)

Molecular Assays Developed for Hantavirus Pulmonary Syndrome

 Hantavirus Pulmonary Syndrome (HPS) is a serious and often fatal disease caused by viruses known as hantaviruses. These anthropozoonotic diseases comprising of two clinical entities: Hemorrhagic Fever with Renal Syndrome (HFRS), which occurs in the Old World, and Hantavirus Pulmonary Syndrome (HPS) in the New World. More...
16 Jan 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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