Molecular Diagnostics

Novel 3-Gene Transcriptional Signature Stratified for Tuberculosis Contacts
The causative agent of tuberculosis, Mycobacterium tuberculosis (Mtb) is an obligate pathogen. The highest risk of tuberculosis arises in the first few months after exposure. Early treatment also offers the opportunity to adopt shorter and simpler treatment regimens, limit pathology, and reduce tuberculosis-associated morbidity. More...04 Mar 2020

Increased Levels of Serum Amyloid-beta Linked to Development of Cardiovascular Disease
A new review article has summarized studies, which suggest that the Alzheimer’s disease (AD) biomarker amyloid-beta (Abeta) has a causitive link to other age-related conditions such as cardiovascular disease (CVD). More...04 Mar 2020


Leukemic Stem Cell Score Predicts Myelodysplastic Syndrome Prognosis
Myelodysplastic syndromes (MDS) are clonal myeloid malignancies arising from hematopoietic stem cells (HSCs), which are characterized by bone marrow (BM) ineffective hematopoiesis, peripheral blood cytopenias, and a propensity to transform to acute myeloid leukemia (AML). More...03 Mar 2020


Heterogeneous Populations of Melanoma Circulating Tumor Cells Detected
Circulating tumor cells (CTCs) can be assessed through a minimally invasive blood sample with potential utility as a predictive, prognostic and pharmacodynamic biomarker. The large heterogeneity of melanoma CTCs has hindered their detection and clinical application. More...02 Mar 2020

In Other News
Fetal Cell-Based NIPT Demonstrated by Droplet Digital PCR
Point-Of-Care Molecular Tests Compared for Pediatric Influenza
Genetic Risk Factors Found in Gestational Diabetes
Combining IL-6 Measurement with a Standard Biomarker Panel Improves Diagnosis of Ovarian Cancer
Novel Blood Tests Predict Progression of Parkinson's Disease
Elevated Levels of Certain Immunoproteosome Components Predict Potential Success of Checkpoint Inhibitor Therapy in Melanoma Patients
Proteogenomic Characterization of Endometrial Carcinoma Analyzed
Uric Acid in Saliva Is a Biomarker for Body Fat Accumulation in Adolescents
Ratio of Serum Very-long-chain to Long-chain Ceramides Is Predictive of Dementia Risk
Factor IX Inhibitor Incidence in Pediatric Hemophilia B Examined
Several Genes Linked to Long QT Syndrome Reappraised
Modular Targeted Capture Assay Detects Clinically Significant Oncology Alterations
Assessment of Circulating Tumor Cells Identifyies Stage III Melanoma Patients at Risk for Relapse
Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans
Autonomous Microchannel Analyzer Combines with Smartphone for Off-Site Disease Diagnostics
Protein Panel Predicts Risk for Development of Cerebral Small Vessel Disease
Blood Test Lead to Earlier Detection of Gastrointestinal Cancers
Rapid Antigenic Diagnostic Test Validated for Ebola Virus Disease
Lipocalin 2 Identified as Biomarker for Differential Diagnosis of Vascular Dementia
CDC Provides Test Protocol for Novel Coronavirus
Lung Cancer Liquid Biopsy Guides MRD-Directed Adjuvant Therapy
Detection of Pathogenic Microorganisms in Semen by Sequencing Sperm RNA
Single-Cell Sequencing Identifies Breast Cancer Risk
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.








