Molecular Diagnostics
Sequencing Could Augment Other Newborn Screening Methods
Newborn screening (NBS) was established as a public health program in the 1960s and is crucial for facilitating detection of certain medical conditions in which early intervention can prevent serious, life-threatening health problems. More...14 Sep 2020
Jagged Ends of Double-Stranded DNA Characterized
Cell-free DNA in plasma has been used for noninvasive prenatal testing and cancer liquid biopsy. The physical properties of cell-free DNA fragments in plasma, such as fragment sizes and ends, have attracted considerable recent interest. More...10 Sep 2020
Loop-Mediated Isothermal Amplification Kit Detects Chagas Disease
Chagas disease (CD), also known as American trypanosomiasis, is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi that affects about six to seven million people worldwide, mainly in endemic areas of 21 Latin American countries. More...07 Sep 2020
Clonal Hematopoiesis Prevalence Determined in Healthy Donors
Clonal hematopoiesis of indeterminate potential (CHIP) is defined as the presence of a clone at more than 2% of variant allele frequency (VAF) in peripheral blood (PB) of individuals with no evidence of hematologic disease. More...02 Sep 2020
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In Other News
Streamlined Method for Telomere Length Measurement Opens New Cancer Diagnostic Opportunities
Pan-Cancer Study Reveals Extrachromosomal DNA Frequency
Adaptive Immune Cells in Ulcerative Colitis Revealed by Single-Cell Analyses
New Pooling Strategy Increases Efficiency and Reduces Cost of COVID-19 PCR Tests
An Extracellular Vesicle-Based Liquid Biopsy for Early Cancer Detection
Loop-Mediated Isothermal Amplification-Assay Rapidly Diagnoses COVID-19
Newborn Exome Sequencing Locates Inborn Errors of Metabolism
Gene Panel Predicts Likely Survival Time for Ovarian Cancer Patients
Single-Cell Analysis Provides New Insights into Mitochondrial Diseases
Isoform-Specific Loss Of Dystonin Causes Charcot-Marie-Tooth Disease
Blood Bank NAT-Based Assay Prevents Transfusion-Transmitted Malaria
Circulating tumor DNA Test Predicts Immunotherapy Response
Lab Profiles Differentiate MIS-C From Severe Pediatric COVID-19
Two Simple Methods Prepare DNA Suitable For Digital PCR
Elevated Glycolated Hemoglobin in Young People Predicts Likelihood of Diabetes or Cardiovascular Disease in Adulthood
Diagnostic Test Identifies Resistance Mutation that Enables Use of Inexpensive, Single Dose Gonorrhea Drug
Panel of Five Serum Biomarkers Identifies COVID-19 Patients at High Risk to Develop Serious Complications
Host Genetic, Environmental Factors Influence Urinary Tract Microbiome
Automated Malaria Diagnosis Enhanced by Deep Neural Networks
Phosphorylated-Tau Blood Test Identifies Asymptomatic Alzheimer’s Disease
Somatic Evolution Identified in Non-Neoplastic IBD-Affected Colon
Liquid Biopsy Test Accurately Detects Cancer in Nonsymptomatic Individuals
Elevated Angiotensin 1–7/Angiotensin II Ratio Predicts Favorable Outcomes in Patients with Heart Failure with Potential Link to COVID-19 Patients
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.